Macroscale Hub

Magnetic resonance imaging (MRI) and positron emission tomography (PET) are key imaging techniques to examine brain morphology and pathology in vivo. Synergistic effects may arise from the ability of PET to detect and quantify pathophysiological processes with very high sensitivity, and the ability of MRI to provide complementary morphological information due to the higher spatial resolution. Applying PET/MRI methods to preclinical animal models enables new (longitudinal) experimental designs and provides the potential for direct translation, thereby reducing the gap between clinical and experimental research. The SyNergy Macroscale Hub provides state-of-the-art preclinical scanners, imaging protocols, and processing pipelines for small animal PET/MRI. 

Contact

Ulrike Schillinger

ISD, Feodor-Lynen-Str. 17, 81377 Munich 

The aim of the Translational Hub is to develop translational projects between basic science and clinical application to bridge this translational gap.

The Hub will assist with the development of translational projects by

• assessing the clinical need
  
• analyzing the feasibility
  
• designing clinical trials
  
• identifying academic and commercial partners
  

Translational projects that can be developed with the hub may encompass the development of diagnostic strategies or biomarkers as well as the identification of novel therapeutic strategies based on repurposed or novel drugs.

The hub will also act as a bridge and mediate the contact between basic researchers and supporting structures, such as academic/clinical research organizations (A/CRO), technology transfer organizations (TTO), intellectual property organizations (IPO) and others.

Contact

Paul Lingor

Neuro-Kopf-Zentrum MRI, Ismaninger Straße 22, 81675 Munich