Tschöp, Matthias

2024

Grandl G, Collden G, Feng J, Bhattacharya S, Klingelhuber F, Schomann L, Bilekova S, Ansarullah, Xu W, Far FF, Tost M, Gruber T, Bastidas-Ponce A, Zhang Q, Novikoff A, Liskiewicz A, Liskiewicz D, Garcia-Caceres C, Feuchtinger A, Tschöp MH, Krahmer N, Lickert H, Müller TD. Global, neuronal or β cell-specific deletion of inceptor improves glucose homeostasis in male mice with diet-induced obesity. Nat Metab. 2024 Mar;6(3):448-457. doi: 10.1038/s42255-024-00991-3. Epub 2024 Feb 28. PMID: 38418586; PMCID: PMC10963260.

2023

González-García I, García-Clavé E, Cebrian-Serrano A, Le Thuc O, Contreras RE, Xu Y, Gruber T, Schriever SC, Legutko B, Lintelmann J, Adamski J, Wurst W, Müller TD, Woods SC, Pfluger PT, Tschöp MH, Fisette A, García-Cáceres C (2023). Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1. Cell Metab. 2023 Mar 7;35(3):438-455.e7. doi: 10.1016/j.cmet.2023.02.004. PMID: 36889283.
Sachs S, Götz A, Finan B, Feuchtinger A, DiMarchi RD, Döring Y, Weber C, Tschöp MH, Müller TD, Hofmann SM (2023). GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease. Cardiovasc Diabetol. 2023 Aug 17;22(1):217. doi: 10.1186/s12933-023-01940-2. PMID: 37592302; PMCID: PMC10436634.

2022

Maity-Kumar G, Ständer L, DeAngelis M, Lee S, Molenaar A, Becker L, Garrett L, Amerie OV, Hoelter SM, Wurst W, Fuchs H, Feuchtinger A, Gailus-Durner V, Garcia-Caceres C, Othman AE, Brockmann C, Schöffling VI, Beiser K, Krude H, Mroz PA, Hofmann S, Tuckermann J, DiMarchi RD, Hrabe de Angelis M, Tschöp MH, Pfluger PT, Müller TD (2022). Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome. Mol Metab. 2022 Oct 18:101616. doi: 10.1016/j.molmet.2022.101616. Epub ahead of print. PMID: 36270613.

2021

Gruber T, Pan C, Contreras RE, Wiedemann T, Morgan DA, Skowronski AA, Lefort S, De Bernardis Murat C, Le Thuc O, Legutko B, Ruiz-Ojeda FJ, Fuente-Fernández M, García-Villalón AL, González-Hedström D, Huber M, Szigeti-Buck K, Müller TD, Ussar S, Pfluger P, Woods SC, Ertürk A, LeDuc CA, Rahmouni K, Granado M, Horvath TL, Tschöp MH, García-Cáceres C (2021). Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension. Cell Metab. 2021 Apr 30:S1550-4131(21)00173-X. doi: 10.1016/j.cmet.2021.04.007. Epub ahead of print. PMID: 33951475.

2020

Baumann P, Schriever SC, Kullmann S, Zimprich A, Peter A, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Wurst W, Tschöp MH, Heni M, Hölter SM, Pfluger PT (2020). Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans. Brain Behav. 2020 Nov 1:e01928. doi: 10.1002/brb3.1928. Epub ahead of print. PMID: 33131190.
Schriever SC, Kabra DG, Pfuhlmann K, Baumann P, Baumgart EV, Nagler J, Seebacher F, Harrison L, Irmler M, Kullmann S, Corrêa-da-Silva F, Giesert F, Jain R, Schug H, Castel J, Martinez S, Wu M, Häring HU, Hrabe de Angelis M, Beckers J, Müller TD, Stemmer K, Wurst W, Rozman J, Nogueiras R, De Angelis M, Molkentin JD, Krahmer N, Yi CX, Schmidt MV, Luquet S, Heni M, Tschoep MH, Pfluger PT (2020). Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity. J Clin Invest. 2020;136363. doi:10.1172/JCI136363 [published online ahead of print, 2020 Aug 11]
Zeggini E, Baumann M, Götz M, Herzig S, Hrabe de Angelis M, Tschöp MH (2020). Biomedical Research Goes Viral: Dangers and Opportunities. Cell. 2020;S0092-8674(20)30576-6. doi:10.1016/j.cell.2020.05.014 [published online ahead of print, 2020 May 11]

2019

Baumann P, Schriever SC, Kullmann S, Zimprich A, Feuchtinger A, Amarie O, Peter A, Walch A, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Wurst W, Tschöp MH, Heni M, Hölter SM, Pfluger PT (2019). Dusp8 affects hippocampal size and behavior in mice and humans. Sci Rep. 2019 Dec 20;9(1):19483. doi: 10.1038/s41598-019-55527-7.
von Gamm M, Schaub A, Jones AN, Wolf C, Behrens G, Lichti J, Essig K, Macht A, Pircher J, Ehrlich A, Davari K, Chauhan D, Busch B, Wurst W, Feederle R, Feuchtinger A, Tschöp MH, Friedel CC, Hauck SM, Sattler M, Geerlof A, Hornung V, Heissmeyer V, Schulz C, Heikenwalder M, Glasmacher E (2019). Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3. J Exp Med. 2019 May 24. pii: jem.20181762. doi: 10.1084/jem.20181762. [Epub ahead of print]