Plesnila, Nikolaus

2024

Groschup B, Calandra GM, Raitmayr C, Shrouder J, Llovera G, Zaki AG, Burgstaller S, Bischof H, Eroglu E, Liesz A, Malli R, Filser S, Plesnila N. Probing intracellular potassium dynamics in neurons with the genetically encoded sensor lc-LysM GEPII 1.0 in vitro and in vivo. Sci Rep. 2024 Jun 14;14(1):13753. doi: 10.1038/s41598-024-62993-1. PMID: 38877089; PMCID: PMC11178854.
Kepp KP, Aavitsland P, Ballin M, Balloux F, Baral S, Bardosh K, Bauchner H, Bendavid E, Bhopal R, Blumstein DT, Boffetta P, Bourgeois F, Brufsky A, Collignon PJ, Cripps S, Cristea IA, Curtis N, Djulbegovic B, Faude O, Flacco ME, Guyatt GH, Hajishengallis G, Hemkens LG, Hoffmann T, Joffe AR, Klassen TP, Koletsi D, Kontoyiannis DP, Kuhl E, La Vecchia C, Lallukka T, Lambris J, Levitt M, Makridakis S, Maltezou HC, Manzoli L, Marusic A, Mavragani C, Moher D, Mol BW, Muka T, Naudet F, Noble PW, Nordström A, Nordström P, Pandis N, Papatheodorou S, Patel CJ, Petersen I, Pilz S, Plesnila N, Ponsonby AL, Rivas MA, Saltelli A, Schabus M, Schippers MC, Schünemann H, Solmi M, Stang A, Streeck H, Sturmberg JP, Thabane L, Thombs BD, Tsakris A, Wood SN, Ioannidis JPA. Panel stacking is a threat to consensus statement validity. J Clin Epidemiol. 2024 Jun 17:111428. doi: 10.1016/j.jclinepi.2024.111428. Epub ahead of print. PMID: 38897481.
Kislinger G, Fabig G, Wehn A, Rodriguez L, Jiang H, Niemann C, Klymchenko AS, Plesnila N, Misgeld T, Müller-Reichert T, Khalin I, Schifferer M. Combining array tomography with electron tomography provides insights into leakiness of the blood-brain barrier in mouse cortex. Elife. 2024 Aug 5;12:RP90565. doi: 10.7554/eLife.90565. PMID: 39102289; PMCID: PMC11299977.
Simats A, Zhang S, Messerer D, Chong F, Beşkardeş S, Chivukula AS, Cao J, Besson-Girard S, Montellano FA, Morbach C, Carofiglio O, Ricci A, Roth S, Llovera G, Singh R, Chen Y, Filser S, Plesnila N, Braun C, Spitzer H, Gokce O, Dichgans M, Heuschmann PU, Hatakeyama K, Beltrán E, Clauss S, Bonev B, Schulz C, Liesz A. Innate immune memory after brain injury drives inflammatory cardiac dysfunction. Cell. 2024 Jul 12:S0092-8674(24)00702-5. doi: 10.1016/j.cell.2024.06.028. Epub ahead of print. PMID: 39043180.
Wehn A, Khalin I, Hu S, Harapan BN, Mao X, Cheng S, Plesnila N, Terpolilli NA. Bradykinin 2 receptors (B2R) mediate long term neurocognitive deficits after experimental traumatic brain injury. J Neurotrauma. 2024 May 31. doi: 10.1089/neu.2024.0042. Epub ahead of print. PMID: 38818807.
Wehn AC, Krestel E, Harapan BN, Klymchenko A, Plesnila N, Khalin I. To see or not to see: In vivo nanocarrier detection methods in the brain and their challenges. J Control Release. 2024 Jul;371:216-236. doi: 10.1016/j.jconrel.2024.05.044. Epub 2024 May 31. PMID: 38810705.
Yoshimura S, Dorok M, Mamrak U, Wehn A, Krestel E, Khalin I, Plesnila N. Reliable infarction of the middle cerebral artery territory in C57BL/6 mice using pterygopalatine artery ligation and filament optimization - The PURE-MCAo model. J Cereb Blood Flow Metab. 2024 Oct 7:271678X241281841. doi: 10.1177/0271678X241281841. Epub ahead of print. PMID: 39370987.

2023

Hu S, Exner C, Sienel RI, Wehn A, Seker B, Magdane Boldoczki F, Guo Y, Duering M, Pasternak O, Plesnila N, Schwarzmaier SM (2023). Characterization of Vasogenic and Cytotoxic Brain Edema Formation after experimental TBI by Free Water Diffusion MRI. J Neurotrauma. 2023 Sep 30. doi: 10.1089/neu.2023.0222. Epub ahead of print. PMID: 37776177.

Kastberger B, Winter S, Brandstätter H, Biller J, Wagner W, Plesnila N. Treatment with Cerebrolysin Prolongs Lifespan in a Mouse Model of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. Adv Biol (Weinh). 2023 Dec 7:e2300439. doi: 10.1002/adbi.202300439. Epub ahead of print. PMID: 38062874.
Kolabas ZI, Kuemmerle LB, Perneczky R, Förstera B, Ulukaya S, Ali M, Kapoor S, Bartos LM, Büttner M, Caliskan OS, Rong Z, Mai H, Höher L, Jeridi D, Molbay M, Khalin I, Deligiannis IK, Negwer M, Roberts K, Simats A, Carofiglio O, Todorov MI, Horvath I, Ozturk F, Hummel S, Biechele G, Zatcepin A, Unterrainer M, Gnörich J, Roodselaar J, Shrouder J, Khosravani P, Tast B, Richter L, Díaz-Marugán L, Kaltenecker D, Lux L, Chen Y, Zhao S, Rauchmann BS, Sterr M, Kunze I, Stanic K, Kan VWY, Besson-Girard S, Katzdobler S, Palleis C, Schädler J, Paetzold JC, Liebscher S, Hauser AE, Gokce O, Lickert H, Steinke H, Benakis C, Braun C, Martinez-Jimenez CP, Buerger K, Albert NL, Höglinger G, Levin J, Haass C, Kopczak A, Dichgans M, Havla J, Kümpfel T, Kerschensteiner M, Schifferer M, Simons M, Liesz A, Krahmer N, Bayraktar OA, Franzmeier N, Plesnila N, Erener S, Puelles VG, Delbridge C, Bhatia HS, Hellal F, Elsner M, Bechmann I, Ondruschka B, Brendel M, Theis FJ, Erturk A (2023). Distinct molecular profiles of skull bone marrow in health and neurological disorders. Cell. 2023 Aug 3:S0092-8674(23)00742-0. doi: 10.1016/j.cell.2023.07.009. Epub ahead of print. PMID: 37562402
Lin X, Khalin I, Harapan BN, Terpolilli NA, Schwarting J, Plesnila N. (2023). Perivascular Macrophages Mediate Microvasospasms After Experimental Subarachnoid Hemorrhage. Stroke. 2023 Jun 16. doi: 10.1161/STROKEAHA.122.042290. Epub ahead of print. PMID: 37325921.
Lucija Bahire K, Maļuhins R, Bello F, Valero Freitag S, Jeļisejevs I, Gile R, Upīte J, Plesnila N, Jansone B (2023). Hemispheric analysis of mitochondrial Complex I and II activity in the mouse model of ischemia-reperfusion-induced injury. Mitochondrion. 2023 Feb 8:S1567-7249(23)00014-4. doi: 10.1016/j.mito.2023.02.005. Epub ahead of print. PMID: 36764500.
Merino-Serrais P, Plaza-Alonso S, Hellal F, Valero-Freitag S, Kastanauskaite A, Plesnila N, DeFelipe J. Structural changes of CA1 pyramidal neurons after stroke in the contralesional hippocampus. Brain Pathol. 2023 Nov 27:e13222. doi: 10.1111/bpa.13222. Epub ahead of print. PMID: 38012061.
Pham T, Hussein T, Calis D, Bischof H, Skrabak D, Cruz Santos M, Maier S, Spähn D, Kalina D, Simonsig S, Ehinger R, Groschup B, Knipper M, Plesnila N, Ruth P, Lukowski R, Matt L (2023). BK channels sustain neuronal Ca2+ oscillations to support hippocampal long-term potentiation and memory formation. Cell Mol Life Sci. 2023 Nov 21;80(12):369. doi: 10.1007/s00018-023-05016-y. PMID: 37989805; PMCID: PMC10663188.
Schwarting J, Harapan BN, Lin X, Plesnila N, Terpolilli NA (2023). Nimodipine Reduces Microvasospasms After Experimental Subarachnoid Hemorrhage. Stroke. 2023 Sep 7. doi: 10.1161/STROKEAHA.123.043976. Epub ahead of print. PMID: 37675614.
Schwarting J, Nehrkorn K, Harapan BN, Balbi M, Terpolilli NA, Plesnila N (2023). Pericytes Are Not Associated With Reduced Capillary Perfusion After Experimental Subarachnoid Hemorrhage. Stroke. 2023 Jun 29. doi: 10.1161/STROKEAHA.123.042936. Epub ahead of print. PMID: 37381898.
Sienel RI, Mamrak U, Biller J, Roth S, Zellner A, Parakaw T, Khambata RS, Liesz A, Haffner C, Ahluwalia A, Seker BF, Plesnila N. Inhaled nitric oxide suppresses neuroinflammation in experimental ischemic stroke. J Neuroinflammation. 2023 Dec 15;20(1):301. doi: 10.1186/s12974-023-02988-3. PMID: 38102677; PMCID: PMC10725028.
Shrouder JJ, Calandra GM, Filser S, Varga DP, Besson-Girard S, Mamrak U, Dorok M, Bulut-Impraim B, Seker FB, Gesierich B, Laredo F, Wehn AC, Khalin I, Bayer P, Liesz A, Gokce O, Plesnila N (2023). Continued dysfunction of capillary pericytes promotes no-reflow after experimental stroke in vivo. Brain. 2023 Dec 28:awad401. doi: 10.1093/brain/awad401. Epub ahead of print. PMID: 38153327.

2022

Khalin I, Adarsh N, Schifferer M, Wehn A, Groschup B, Misgeld T, Klymchenko A, Plesnila N (2022). Size-Selective Transfer of Lipid Nanoparticle-Based Drug Carriers Across the Blood Brain Barrier Via Vascular Occlusions Following Traumatic Brain Injury. Small. 2022 Apr 5:e2200302. doi: 10.1002/smll.202200302. Epub ahead of print. PMID: 35384294.
Merino-Serrais P, Plaza-Alonso S, Hellal F, Valero-Freitag S, Kastanauskaite A, Muñoz A, Plesnila N, DeFelipe J (2022). Microanatomical study of pyramidal neurons in the contralesional somatosensory cortex after experimental ischemic stroke. Cereb Cortex. 2022 Mar 30:bhac121. doi: 10.1093/cercor/bhac121. Epub ahead of print. PMID: 35353195.
Schwarzmaier SM, Knarr MRO, Hu S, Ertürk A, Hellal F, Plesnila N (2022). Perfusion pressure determines vascular integrity and histomorphological quality following perfusion fixation of the brain. J Neurosci Methods. 2022 Feb 10;372:109493. doi: 10.1016/j.jneumeth.2022.109493. Epub ahead of print. PMID: 35151669.
Sienel RI, Kataoka H, Kim SW, Seker FB, Plesnila N (2022). Adhesion of Leukocytes to Cerebral Venules Precedes Neuronal Cell Death and Is Sufficient to Trigger Tissue Damage After Cerebral Ischemia. Front Neurol. 2022 Jan 24;12:807658. doi: 10.3389/fneur.2021.807658. PMID: 35140676; PMCID: PMC8818753.
Terpollili NA, Dolp R, Waehner K, Schwarzmaier SM, Rumbler E, Todorov B, Ferrari MD, van den Maagdenberg AMJM, Plesnila N (2022). CaV2.1 channel mutations causing familial hemiplegic migraine type 1 increase the susceptibility for cortical spreading depolarizations and seizures and worsen outcome after experimental traumatic brain injury. Elife. 2022 Mar 3;11:e74923. doi: 10.7554/eLife.74923. PMID: 35238776; PMCID: PMC8920504.
Wilmes M, Pinto Espinoza C, Ludewig P, Stabernack J, Liesz A, Nicke A, Gelderblom M, Gerloff C, Falzoni S, Tolosa E, Di Virgilio F, Rissiek B, Plesnila N, Koch-Nolte F, Magnus T (2022). Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesions. J Neuroinflammation. 2022 Oct 12;19(1):256. doi: 10.1186/s12974-022-02601-z. PMID: 36224611; PMCID: PMC9559872.
Zille M, Plesnila N, Boltze J (2022). Pharmacologically targeting inflammation and improving cerebrospinal fluid circulation improves outcome after subarachnoid haemorrhage. EBioMedicine. 2022 Mar;77:103937. doi: 10.1016/j.ebiom.2022.103937. Epub 2022 Mar 13. PMID: 35290830; PMCID: PMC8921540

2021

Auffenberg E, Hedrich UB, Barbieri R, Miely D, Groschup B, Wuttke TV, Vogel N, Lührs P, Zanardi I, Bertelli S, Spielmann N, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Pusch M, Dichgans M, Lerche H, Gavazzo P, Plesnila N, Freilinger T (2021). Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model. J Clin Invest. 2021 Sep 21:e142202. doi: 10.1172/JCI142202. Epub ahead of print. PMID: 34546973.
Bischof H, Burgstaller S, Springer A, Matt L, Rauter T, Bachkönig OA, Schmidt T, Groschner K, Schindl R, Madl T, Plesnila N, Lukowski R, Graier WF, Malli R (2021). Potassium ions promote hexokinase-II dependent glycolysis. iScience. 2021 Mar 22;24(4):102346. doi: 10.1016/j.isci.2021.102346. PMID: 33870140; PMCID: PMC8047173.
Boltze J, Aronowski JA, Badaut J, Buckwalter MS, Caleo M, Chopp M, Dave KR, Didwischus N, Dijkhuizen RM, Doeppner TR, Dreier JP, Fouad K, Gelderblom M, Gertz K, Golubczyk D, Gregson BA, Hamel E, Hanley DF, Härtig W, Hummel FC, Ikhsan M, Janowski M, Jolkkonen J, Karuppagounder SS, Keep RF, Koerte IK, Kokaia Z, Li P, Liu F, Lizasoain I, Ludewig P, Metz GAS, Montagne A, Obenaus A, Palumbo A, Pearl M, Perez-Pinzon M, Planas AM, Plesnila N, Raval AP, Rueger MA, Sansing LH, Sohrabji F, Stagg CJ, Stetler RA, Stowe AM, Sun D, Taguchi A, Tanter M, Vay SU, Vemuganti R, Vivien D, Walczak P, Wang J, Xiong Y, Zille M (2021). New Mechanistic Insights, Novel Treatment Paradigms, and Clinical Progress in Cerebrovascular Diseases. Front Aging Neurosci. 2021 Jan 28;13:623751. doi: 10.3389/fnagi.2021.623751. PMID: 33584250; PMCID: PMC7876251.
Burgstaller S, Bischof H, Rauter T, Schmidt T, Schindl R, Patz S, Groschup B, Filser S, van den Boom L, Sasse P, Lukowski R, Plesnila N, Graier WF, Malli R (2021). Immobilization of Recombinant Fluorescent Biosensors Permits Imaging of Extracellular Ion Signals. ACS Sens. 2021 Nov 9. doi: 10.1021/acssensors.1c01369. Epub ahead of print. PMID: 34752056.
Chen S, Mao X, Lin X, Wehn A, Hu S, Mamrak U, Khalin I, Wostrack M, Ringel F, Plesnila N, Terpolilli NA (2021). Acid-ion sensing channel 1a deletion reduces chronic brain damage and neurological deficits after experimental traumatic brain injury. J Neurotrauma. 2021 Mar 27. doi: 10.1089/neu.2020.7568. Epub ahead of print. PMID: 33779289.
Chovsepian A, Berchtold D, Winek K, Mamrak U, Ramírez Álvarez I, Dening Y, Golubczyk D, Weitbrecht L, Dames C, Aillery M, Fernandez-Sanz C, Gajewski Z, Dieterich M, Janowski M, Falkai P, Walczak P, Plesnila N, Meisel A, Pan-Montojo F (2021). A Primeval Mechanism of Tolerance to Desiccation Based on Glycolic Acid Saves Neurons in Mammals from Ischemia by Reducing Intracellular Calcium-Mediated Excitotoxicity. Adv Sci (Weinh). 2021 Dec 14:e2103265. doi: 10.1002/advs.202103265. Epub ahead of print. PMID: 34904402.
Khalin I, Severi C, Heimburger D, Wehn A, Hellal F, Reisch A, Klymchenko AS, Plesnila N (2021). Dynamic tracing using ultra-bright labelling and multi-photon microscopy identifies endothelial uptake of poloxamer 188 coated poly(lactic-co-glycolic acid) nano-carriers in vivo. Nanomedicine. 2021 Dec 13:102511. doi: 10.1016/j.nano.2021.102511. Epub ahead of print. PMID: 34915181.
Liu H, Schwarting J, Terpolilli NA, Nehrkorn K, Plesnila N (2021). Scavenging Free Iron Reduces Arteriolar Microvasospasms After Experimental Subarachnoid Hemorrhage. Stroke. 2021 Nov 9:STROKEAHA120033472. doi: 10.1161/STROKEAHA.120.033472. Epub ahead of print. PMID: 34749506.
Pfeiffer S, Tomašcová A, Mamrak U, Haunsberger SJ, Connolly NMC, Resler A, Düssmann H, Weisová P, Jirström E, D'Orsi B, Chen G, Cremona M, Hennessy BT, Plesnila N, Prehn JHM (2021). AMPK-regulated miRNA-210-3p is activated during ischaemic neuronal injury and modulates PI3K-p70S6K signalling. J Neurochem. 2021 Mar 11. doi: 10.1111/jnc.15347. Epub ahead of print. PMID: 33694332.
Schwarting J, Nehrkorn K, Liu H, Plesnila N, Terpolilli NA (2021). Role of Pial Microvasospasms and Leukocyte Plugging for Parenchymal Perfusion after Subarachnoid Hemorrhage Assessed by In Vivo Multi-Photon Microscopy. Int J Mol Sci. 2021 Aug 6;22(16):8444. doi: 10.3390/ijms22168444. PMID: 34445151; PMCID: PMC8395146.
Seker FB, Fan Z, Gesierich B, Gaubert M, Sienel RI, Plesnila N (2021). Neurovascular Reactivity in the Aging Mouse Brain Assessed by Laser Speckle Contrast Imaging and 2-Photon Microscopy: Quantification by an Investigator-Independent Analysis Tool. Front Neurol. 2021 Nov 11;12:745770. doi: 10.3389/fneur.2021.745770. PMID: 34858312; PMCID: PMC8631776.
Tüshaus J, Müller SA, Shrouder J, Arends M, Simons M, Plesnila N, Blobel CP, Lichtenthaler SF (2021). The pseudoprotease iRhom1 controls ectodomain shedding of membrane proteins in the nervous system. FASEB J. 2021 Nov;35(11):e21962. doi: 10.1096/fj.202100936R. PMID: 34613632.
Walter J, Schwarting J, Plesnila N, Terpolilli NA (2021). Influence of Organic Solvents on Secondary Brain Damage after Experimental Traumatic Brain Injury. Neurotrauma Rep. 2020 Nov 6;1(1):148-156. doi: 10.1089/neur.2020.0029. PMID: 34223539; PMCID: PMC8240898.
Wehn AC, Khalin I, Duering M, Hellal F, Culmsee C, Vandenabeele P, Plesnila N, Terpolilli NA (2021). RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury. Acta Neuropathol Commun. 2021 Aug 17;9(1):138. doi: 10.1186/s40478-021-01236-0. PMID: 34404478; PMCID: PMC8369637.
Wiegand TLT, Sollmann N, Bonke EM, Umeasalugo KE, Sobolewski KR, Plesnila N, Shenton ME, Lin AP, Koerte IK (2021). Translational neuroimaging in mild traumatic brain injury. J Neurosci Res. 2021 Mar 31. doi: 10.1002/jnr.24840. Epub ahead of print. PMID: 33789358.

2020

Boltze J, Didwischus N, Merrow M, Dallmann R, Plesnila N. Circadian effects on stroke outcome - Did we not wake up in time for neuroprotection? J Cereb Blood Flow Metab. 2021 Mar;41(3):684-686. doi: 10.1177/0271678X20978711. Epub 2020 Dec 18. PMID: 33337257; PMCID: PMC7907996.
Hu Y, Seker B, Exner C, Zhang J, Plesnila N, Schwarzmaier SM (2020). Longitudinal characterization of blood-brain barrier permeability after experimental traumatic brain injury by in vivo 2-photon microscopy. J Neurotrauma. 2020 Oct 3. doi: 10.1089/neu.2020.7271. Epub ahead of print. PMID: 33012249.
Khalin I, Heimburger D, Melnychuk N, Collot M, Groschup B, Hellal F, Reisch A, Plesnila N, Klymchenko AS (2020). Ultrabright Fluorescent Polymeric Nanoparticles with Stealth Pluronic Shell for Live Tracking in Mouse Brain. ACS Nano. 2020;10.1021/acsnano.0c01505. doi:10.1021/acsnano.0c01505 [published online ahead of print, 2020 Jul 17]
Lenz IJ, Plesnila N, Terpolilli NA (2020). Role of endothelial nitric oxide synthase for early brain injury after subarachnoid hemorrhage in mice. J Cereb Blood Flow Metab. 2020 Nov 30:271678X20973787. doi: 10.1177/0271678X20973787. Epub ahead of print. PMID: 33256507.
Ramírez-Fernández A, Urbina-Treviño L, Conte G, Alves M, Rissiek B, Durner A, Scalbert N, Zhang J, Magnus T, Koch-Nolte F, Plesnila N, Deussing JM, Engel T, Kopp R, Nicke A (2020). Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model. Sci Rep. 2020 Nov 16;10(1):19876. doi: 10.1038/s41598-020-76428-0. PMID: 33199725; PMCID: PMC7669894.
Rauen K, Reichelt L, Probst P, Schäpers B, Müller F, Jahn K, Plesnila N (2020). Quality of life up to 10 years after traumatic brain injury: a cross-sectional analysis. Health Qual Life Outcomes. 2020;18(1):166. Published 2020 Jun 4. doi:10.1186/s12955-020-01391-3
Rauen K, Späni CB, Tartaglia MC, Ferretti MT, Reichelt L, Probst P, Schäpers B, Müller F, Jahn K, Plesnila N (2020). Quality of life after traumatic brain injury: a cross-sectional analysis uncovers age- and sex-related differences over the adult life span. Geroscience. 2020 Oct 17. doi: 10.1007/s11357-020-00273-2. Epub ahead of print. PMID: 33070278.
Rauen K, Reichelt L, Probst P, Schäpers B, Müller F, Jahn K, Plesnila N (2020). Decompressive Craniectomy Is Associated With Good Quality of Life Up to 10 Years After Rehabilitation From Traumatic Brain Injury. Crit Care Med. 2020;10.1097/CCM.0000000000004387. doi:10.1097/CCM.0000000000004387 [published online ahead of print, 2020 May 18].

2019

Balbi M, Vega MJ, Lourbopoulos A, Terpolilli NA, Plesnila N (2019). Long-term impairment of neurovascular coupling following experimental subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2019 Jul 11:271678X19863021. doi: 10.1177/0271678X19863021. [Epub ahead of print]
Griemert EV, Schwarzmaier SM, Hummel R, Gölz C, Yang D, Neuhaus W, Burek M, Förster CY, Petkovic I, Trabold R, Plesnila N, Engelhard K, Schäfer MK, Thal SC. Plasminogen activator inhibitor-1 augments damage by impairing fibrinolysis after traumatic brain injury. Ann Neurol. 2019 May;85(5):667-680. doi: 10.1002/ana.25458. Epub 2019 Mar 30. PMID: 30843275; PMCID: PMC6593843.
Mao X, Terpolilli NA, Wehn A, Chen S, Hellal F, Liu B, Seker B, Plesnila N (2019). Progressive histopathological damage occurring up to one year after experimental traumatic brain injury is associated with cognitive decline and depression-like behavior. J Neurotrauma. 2019 Dec 17. doi: 10.1089/neu.2019.6510. [Epub ahead of print]
Panahpour H, Terpolilli NA, Schaffert D, Culmsee C, Plesnila N (2019). Central Application of Aliskiren, a Renin Inhibitor, Improves Outcome After Experimental Stroke Independent of Its Blood Pressure Lowering Effect. Front Neurol. 2019 Sep 4;10:942. doi: 10.3389/fneur.2019.00942. eCollection 2019.
Rauen K, Pop V, Trabold R, Badaut J, Plesnila N (2019). Vasopressin V1a receptors regulate cerebral aquaporin 1 after traumatic brain injury. J Neurotrauma. 2019 Sep 24. doi: 10.1089/neu.2019.6653. [Epub ahead of print]

2018

2017

Balbi M, Koide M, Wellman GC, Plesnila N (2017). Inversion of neurovascular coupling after subarachnoid hemorrhage in vivo. J Cereb Blood Flow Metab. 2017 Jan 1:271678X16686595. doi: 10.1177/0271678X16686595. [Epub ahead of print]
Krieg SM, Trabold R, Plesnila N. Time-Dependent Effects of Arginine-Vasopressin V1 Receptor Inhibition on Secondary Brain Damage after Traumatic Brain Injury. J Neurotrauma. 2017 Apr 1;34(7):1329-1336. doi: 10.1089/neu.2016.4514. Epub 2016 Dec 6. PMID: 27762660.
Llovera G, Benakis C, Enzmann G, Cai R, Arzberger T, Ghasemigharagoz A, Mao X, Malik R, Lazarevic I, Liebscher S, Ertürk A, Meissner L, Vivien D, Haffner C, Plesnila N, Montaner J, Engelhardt B, Liesz A (2017). The choroid plexus is a key cerebral invasion route for T cells after stroke. Acta Neuropathol. 2017 Jul 31. doi: 10.1007/s00401-017-1758-y. [Epub ahead of print]
Tiedt S, Prestel M, Malik R, Schieferdecker N, Düring M, Kautzky V, Stoycheva I, Böck J, Northoff BH, Klein M, Dorn F, Krohn K, Teupser D, Liesz A, Plesnila N, Holdt LM, Dichgans M (2017). RNA-Seq Identifies Circulating miR-125a-5p, miR-125b-5p and miR-143-3p as Potential Biomarkers for Acute Ischemic Stroke. Circ Res. 2017 Jul 19. pii: CIRCRESAHA.117.311572. doi: 10.1161/CIRCRESAHA.117.311572. [Epub ahead of print]

2016

Lourbopoulos A, Mamrak U, Roth S, Balbi M, Shrouder J, Liesz A, Hellal F, Plesnila N (2016). Inadequate food and water intake determine mortality following stroke in mice. J Cereb Blood Flow Metab. 2016 Jul 22. pii: 0271678X16660986. [Epub ahead of print]
Meissner L, Gallozzi M, Balbi M, Schwarzmaier S, Tiedt S, Terpolilli NA, Plesnila N. Temporal Profile of MicroRNA Expression in Contused Cortex after Traumatic Brain Injury in Mice. J Neurotrauma. 2016 Apr 15;33(8):713-20. doi: 10.1089/neu.2015.4077. Epub 2015 Dec 23. PMID: 26426744.
Pan C, Cai R, Quacquarelli FP, Ghasemigharagoz A, Lourbopoulos A, Matryba P, Plesnila N, Dichgans M, Hellal F, Ertürk A (2016). Shrinkage-mediated imaging of entire organs and organisms using uDISCO. Nat Methods. 2016 Aug 22. doi: 10.1038/nmeth.3964. [Epub ahead of print]
Schwarzmaier SM, de Chaumont C, Balbi M, Terpolilli NA, Kleinschnitz C, Gruber A, Plesnila N (2016). The formation of microthrombi in parenchymal microvessels after traumatic brain injury is independent of coagulation factor. XI J Neurotrauma. 2016 Feb 17. [Epub ahead of print]

2015

Balbi M, Ghosh M, Longden TA, Jativa Vega M, Gesierich B, Hellal F, Lourbopoulos A, Nelson MT, Plesnila N (2015). Dysfunction of mouse cerebral arteries during early aging. J Cereb Blood Flow Metab. 2015 Jun 10. doi: 10.1038/jcbfm.2015.107. [Epub ahead of print]
Balbi M, Koide M, Schwarzmaier SM, Wellman GC, Plesnila N (2015). Acute changes in neurovascular reactivity after subarachnoid hemorrhage in vivo. J Cereb Blood Flow Metab. 2015 Dec 16. pii: 0271678X15621253. [Epub ahead of print]
Bühler D, Azghandi S, Schüller K, Plesnila N (2015). Effect of decompressive craniectomy on outcome following subarachnoid hemorrhage in mice. Stroke. 2015 Jan 15. pii: STROKEAHA.114.007703. [Epub ahead of print]
Ghosh M, Balbi M, Hellal F, Dichgans M, Lindauer U, Plesnila N (2015). Pericytes are involved in the pathogenesis of CADASIL. Ann Neurol. 2015 Aug 27. doi: 10.1002/ana.24512. [Epub ahead of print]
Llovera G, Hofmann K, Roth S, Salas-Pérdomo A, Ferrer-Ferrer M, Perego C, Zanier ER, Mamrak U, Rex A, Party H, Agin V, Fauchon C, Orset C, Haelewyn B, De Simoni MG, Dirnagl U, Grittner U, Planas AM, Plesnila N, Vivien D, Liesz A (2015). Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia. Sci Transl Med. 2015 Aug 5;7(299):299ra121. doi: 10.1126/scitranslmed.aaa9853.
Plesnila N (2015). The immune system in traumatic brain injury. Curr Opin Pharmacol. 2015 Nov 21;26:110-117. doi: 10.1016/j.coph.2015.10.008. [Epub ahead of print]
Terpolilli NA, Brem C, Bühler D, Plesnila N (2015). Are We Barking Up the Wrong Vessels? Cerebral Microcirculation After Subarachnoid Hemorrhage. Stroke. 2015 Jul 7. pii: STROKEAHA.115.006353. [Epub ahead of print]
Terpolilli NA, Feiler S, Dienel A, Müller F, Heumos N, Friedrich B, Stover J, Thal S, Schöller K, Plesnila N (2015). Nitric oxide inhalation reduces brain damage, prevents mortality, and improves neurological outcome after subarachnoid hemorrhage by resolving early pial microvasospasms. J Cereb Blood Flow Metab. 2015 Nov 2. pii: 0271678X15605848. [Epub ahead of print]

2014

Bühler D, Schüller K, Plesnila N (2014). Protocol for the Induction of Subarachnoid Hemorrhage in Mice by Perforation of the Circle of Willis with an Endovascular Filament. Transl Stroke Res. 2014 Aug 16. [Epub ahead of print]
Llovera G, Roth S, Plesnila N, Veltkamp R, Liesz A (2014). Modeling stroke in mice: permanent coagulation of the distal middle cerebral artery. J Vis Exp. 2014 Jul 31;(89). doi: 10.3791/51729.
Schwarzmaier SM, Plesnila N (2014). Contributions of the immune system to the pathophysiology of traumatic brain injury - evidence by intravital microscopy. Front Cell Neurosci. 2014 Nov 4;8:358. eCollection 2014.

2013

Plesnila, Nikolaus

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