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                                                          4. Perocchi, Fabiana

                                                          Perocchi, Fabiana

                                                          2024
                                                          • Brunner S, Höring M, Liebisch G, Schweizer S, Scheiber J, Giansanti P, Hidrobo M, Hermeling S, Oeckl J, Prudente de Mello N, Perocchi F, Seeliger C, Strohmeyer A, Klingenspor M, Plagge J, Küster B, Burkhardt R, Janssen KP, Ecker J. Mitochondrial lipidomes are tissue specific - low cholesterol contents relate to UCP1 activity. Life Sci Alliance. 2024 Jun 6;7(8):e202402828. doi: 10.26508/lsa.202402828. PMID: 38843936; PMCID: PMC11157264.
                                                          • Delgado de la Herran H, Vecellio Reane D, Cheng Y, Katona M, Hosp F, Greotti E, Wettmarshausen J, Patron M, Mohr H, Prudente de Mello N, Chudenkova M, Gorza M, Walia S, Feng MS, Leimpek A, Mielenz D, Pellegata NS, Langer T, Hajnóczky G, Mann M, Murgia M, Perocchi F. Systematic mapping of mitochondrial calcium uniporter channel (MCUC)-mediated calcium signaling networks. EMBO J. 2024 Sep 11. doi: 10.1038/s44318-024-00219-w. Epub ahead of print. PMID: 39261663.

                                                          • Keipert S, Gaudry MJ, Kutschke M, Keuper M, Dela Rosa MAS, Cheng Y, Monroy Kuhn JM, Laterveer R, Cotrim CA, Giere P, Perocchi F, Feederle R, Crichton PG, Lutter D, Jastroch M. Two-stage evolution of mammalian adipose tissue thermogenesis. Science. 2024 Jun 7;384(6700):1111-1117. doi: 10.1126/science.adg1947. Epub 2024 Jun 6. PMID: 38843333.

                                                          • Lebas M, Chinigò G, Courmont E, Bettaieb L, Machmouchi A, Goveia J, Beatovic A, Van Kerckhove J, Robil C, Angulo FS, Vedelago M, Errerd A, Treps L, Gao V, Delgado De la Herrán HC, Mayeuf-Louchart A, L'homme L, Chamlali M, Dejos C, Gouyer V, Garikipati VNS, Tomar D, Yin H, Fukui H, Vinckier S, Stolte A, Conradi LC, Infanti F, Lemonnier L, Zeisberg E, Luo Y, Lin L, Desseyn JL, Pickering J, Kishore R, Madesh M, Dombrowicz D, Perocchi F, Staels B, Pla AF, Gkika D, Cantelmo AR. Integrated single-cell RNA-seq analysis reveals mitochondrial calcium signaling as a modulator of endothelial-to-mesenchymal transition. Sci Adv. 2024 Aug 9;10(32):eadp6182. doi: 10.1126/sciadv.adp6182. Epub 2024 Aug 9. PMID: 39121218; PMCID: PMC11313856.

                                                          2023

                                                          • de Mello NP, Fecher C, Pastor AM, Perocchi F, Misgeld T (2023). Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice. Nat Protoc. 2023 Jun 16. doi: 10.1038/s41596-023-00831-w. Epub ahead of print. PMID: 37328604
                                                          • Tai YH, Engels D, Locatelli G, Emmanouilidis I, Fecher C, Theodorou D, Müller SA, Licht-Mayer S, Kreutzfeldt M, Wagner I, de Mello NP, Gkotzamani SN, Trovò L, Kendirli A, Aljović A, Breckwoldt MO, Naumann R, Bareyre FM, Perocchi F, Mahad D, Merkler D, Lichtenthaler SF, Kerschensteiner M, Misgeld T (2023). Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions. Nat Metab. 2023 Jul 10. doi: 10.1038/s42255-023-00838-3. Epub ahead of print. PMID: 37430025.

                                                          2022

                                                          • Harbauer AB, Schneider A, Wohlleber D (2022). Analysis of Mitochondria by Single-Organelle Resolution. Annu Rev Anal Chem (Palo Alto Calif). 2022 Feb 18. doi: 10.1146/annurev-anchem-061020-111722. Epub ahead of print. PMID: 35303775.
                                                          • Metzner K, Darawsha O, Wang M, Gaur N, Cheng Y, Rödiger A, Frahm C, Witte OW, Perocchi F, Axer H, Grosskreutz J, Brill MS (2022). Age-dependent increase of cytoskeletal components in sensory axons in human skin. Front Cell Dev Biol. 2022 Nov 1;10:965382. doi: 10.3389/fcell.2022.965382. PMID: 36393849; PMCID: PMC9664158.

                                                          2021

                                                          • Arduino DM, Goh V, Mokranjac D, Perocchi F (2021). Drug Discovery Assay to Identify Modulators of the Mitochondrial Ca2+ Uniporter. Methods Mol Biol. 2021;2277:69-89. doi: 10.1007/978-1-0716-1270-5_5. PMID: 34080145.
                                                          • Delgado de la Herran HC, Cheng Y, Perocchi F (2021). Towards a systems-level understanding of mitochondrial biology. Cell Calcium. 2021 Feb 1;95:102364. doi: 10.1016/j.ceca.2021.102364. Epub ahead of print. PMID: 33601101.
                                                          • Sander P, Feng M, Schweitzer MK, Wilting F, Gutenthaler SM, Arduino DM, Fischbach S, Dreizehnter L, Moretti A, Gudermann T, Perocchi F, Schredelseker J (2021). Approved drugs ezetimibe and disulfiram enhance mitochondrial Ca2+ uptake and suppress cardiac arrhythmogenesis. Br J Pharmacol. 2021 Jul 21. doi: 10.1111/bph.15630. Epub ahead of print. PMID: 34287836.
                                                          • Stavsky A, Stoler O, Kostic M, Katoshevsky T, Assali EA, Savic I, Amitai Y, Prokisch H, Leiz S, Daumer-Haas C, Fleidervish I, Perocchi F, Gitler D, Sekler I (2021). Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation. Commun Biol. 2021 Jun 2;4(1):666. doi: 10.1038/s42003-021-02114-0. Erratum in: Commun Biol. 2021 Jun 14;4(1):755. PMID: 34079053; PMCID: PMC8172942.

                                                          2020

                                                          • Lampl S, Janas MK, Donakonda S, Brugger M, Lohr K, Schneider A, Manske K, Sperl LE, Kläger S, Küster B, Wettmarshausen J, Müller C, Laschinger M, Hartmann D, Hüser N, Perocchi F, Schmitt-Kopplin P, Hagn F, Zender L, Hornung V, Borner C, Pichlmair A, Kashkar H, Klingenspor M, Prinz M, Schreiner S, Conrad M, Jost PJ, Zischka H, Steiger K, Krönke M, Zehn D, Protzer U, Heikenwälder M, Knolle PA, Wohlleber D. Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes. J Hepatol. 2020 Dec;73(6):1347-1359. doi: 10.1016/j.jhep.2020.06.026. Epub 2020 Jun 26. PMID: 32598967.
                                                          • Meul T, Berschneider K, Schmitt S, Mayr CH, Mattner LF, Schiller HB, Yazgili AS, Wang X, Lukas C, Schlesser C, Prehn C, Adamski J, Graf E, Schwarzmayr T, Perocchi F, Kukat A, Trifunovic A, Kremer L, Prokisch H, Popper B, von Toerne C, Hauck SM, Zischka H, Meiners S (2020). Mitochondrial Regulation of the 26S Proteasome. Cell Rep. 2020;32(8):108059. doi:10.1016/j.celrep.2020.108059
                                                          • Pittis AA, Goh V, Cebrian-Serrano A, Wettmarshausen J, Perocchi F, Gabaldón T (2020). Discovery of EMRE in fungi resolves the true evolutionary history of the mitochondrial calcium uniporter. Nat Commun. 2020;11(1):4031. Published 2020 Aug 12. doi:10.1038/s41467-020-17705-4

                                                          2019

                                                          • Fecher C, Trovò L, Müller SA, Snaidero N, Wettmarshausen J, Heink S, Ortiz O, Wagner I, Kühn R, Hartmann J, Karl RM, Konnerth A, Korn T, Wurst W, Merkler D, Lichtenthaler SF, Perocchi F, Misgeld T (2019). Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity. Nat Neurosci. 2019 Sep 9. doi: 10.1038/s41593-019-0479-z. [Epub ahead of print]
                                                          • Yim A, Koti P, Bonnard A, Marchiano F, Dürrbaum M, Garcia-Perez C, Villaveces J, Gamal S, Cardone G, Perocchi F, Storchova Z, Habermann BH (2019). mitoXplorer, a visual data mining platform to systematically analyze and visualize mitochondrial expression dynamics and mutations. Nucleic Acids Res. 2019 Dec 4. pii: gkz1128. doi: 10.1093/nar/gkz1128. [Epub ahead of print]

                                                          2018

                                                          • Wettmarshausen J, Goh V, Huang KT, Arduino DM, Tripathi U, Leimpek A, Cheng Y, Pittis AA, Gabaldón T, Mokranjac D, Hajnóczky G, Perocchi F (2018). MICU1 Confers Protection from MCU-Dependent Manganese Toxicity. Cell Rep. 2018 Nov 6;25(6):1425-1435.e7. doi: 10.1016/j.celrep.2018.10.037.

                                                          2017

                                                          • Arduino DM, Wettmarshausen J, Vais H, Navas-Navarro P, Cheng Y, Leimpek A, Ma Z, Delrio-Lorenzo A, Giordano A, Garcia-Perez C, Médard G, Kuster B, García-Sancho J, Mokranjac D, Foskett JK, Alonso MT, Perocchi F (2017). Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening. Mol Cell. 2017 Aug 17;67(4):711-723.e7. doi: 10.1016/j.molcel.2017.07.019.

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                                                          SyNergy is funded by the Deutsche Forschungsgemeinschaft (German Research Foundation) within the framework of the German Excellence Strategy (EXC 2145 SyNergy – ID 390857198). The Excellence Strategy promotes outstanding research at German universities. 

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