Misgeld, Thomas

2024

Ancău M, Tanti GK, Butenschoen VM, Gempt J, Yakushev I, Nekolla S, Mühlau M, Scheunemann C, Heininger S, Löwe B, Löwe E, Baer S, Fischer J, Reiser J, Ayachit SS, Liesche-Starnecker F, Schlegel J, Matiasek K, Schifferer M, Kirschke JS, Misgeld T, Lueth T, Hemmer B. Validating a minipig model of reversible cerebral demyelination using human diagnostic modalities and electron microscopy. EBioMedicine. 2024 Feb 1;100:104982. doi: 10.1016/j.ebiom.2024.104982. Epub ahead of print. PMID: 38306899.
Kislinger G, Fabig G, Wehn A, Rodriguez L, Jiang H, Niemann C, Klymchenko AS, Plesnila N, Misgeld T, Müller-Reichert T, Khalin I, Schifferer M. Combining array tomography with electron tomography provides insights into leakiness of the blood-brain barrier in mouse cortex. Elife. 2024 Aug 5;12:RP90565. doi: 10.7554/eLife.90565. PMID: 39102289; PMCID: PMC11299977.
Mauker P, Beckmann D, Kitowski A, Heise C, Wientjens C, Davidson AJ, Wanderoy S, Fabre G, Harbauer AB, Wood W, Wilhelm C, Thorn-Seshold J, Misgeld T, Kerschensteiner M, Thorn-Seshold O. Fluorogenic Chemical Probes for Wash-free Imaging of Cell Membrane Damage in Ferroptosis, Necrosis, and Axon Injury. J Am Chem Soc. 2024 Apr 9. doi: 10.1021/jacs.3c07662. Epub ahead of print. PMID: 38592946.
Saller BS, Wöhrle S, Fischer L, Dufossez C, Ingerl IL, Kessler S, Mateo-Tortola M, Gorka O, Lange F, Cheng Y, Neuwirt E, Marada A, Koentges C, Urban C, Aktories P, Reuther P, Giese S, Kirschnek S, Mayer C, Pilic J, Falquez-Medina H, Oelgeklaus A, Deepagan VG, Shojaee F, Zimmermann JA, Weber D, Tai YH, Crois A, Ciminski K, Peyronnet R, Brandenburg KS, Wu G, Baumeister R, Heimbucher T, Rizzi M, Riedel D, Helmstädter M, Buescher J, Neumann K, Misgeld T, Kerschensteiner M, Walentek P, Kreutz C, Maurer U, Rambold AS, Vince JE, Edlich F, Malli R, Häcker G, Kierdorf K, Meisinger C, Köttgen A, Jakobs S, Weber ANR, Schwemmle M, Groß CJ, Groß O. Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation. Immunity. 2024 Nov 15:S1074-7613(24)00492-8. doi: 10.1016/j.immuni.2024.10.012. Epub ahead of print. PMID: 39571574.

2023

Askari S, Misgeld T (2023). Brain imaging turned inside out. Nat Biotechnol. 2023 Nov 13. doi: 10.1038/s41587-023-02036-8. Epub ahead of print. PMID: 37957343.
de Mello NP, Fecher C, Pastor AM, Perocchi F, Misgeld T (2023). Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice. Nat Protoc. 2023 Jun 16. doi: 10.1038/s41596-023-00831-w. Epub ahead of print. PMID: 37328604.
Kislinger G, Niemann C, Rodriguez L, Jiang H, Fard MK, Snaidero N, Schumacher AM, Kerschensteiner M, Misgeld T, Schifferer M (2023). Neurons on tape: Automated Tape Collecting Ultramicrotomy-mediated volume EM for targeting neuropathology. Methods Cell Biol. 2023;177:125-170. doi: 10.1016/bs.mcb.2023.01.012. Epub 2023 Feb 24. PMID: 37451765.
Mezydlo A, Treiber N, Ullrich Gavilanes EM, Eichenseer K, Ancău M, Wens A, Ares Carral C, Schifferer M, Snaidero N, Misgeld T, Kerschensteiner M (2023). Remyelination by surviving oligodendrocytes is inefficient in the inflamed mammalian cortex. Neuron. 2023 Apr 13:S0896-6273(23)00227-1. doi: 10.1016/j.neuron.2023.03.031. Epub ahead of print. PMID: 37071991.
Tai YH, Engels D, Locatelli G, Emmanouilidis I, Fecher C, Theodorou D, Müller SA, Licht-Mayer S, Kreutzfeldt M, Wagner I, de Mello NP, Gkotzamani SN, Trovò L, Kendirli A, Aljović A, Breckwoldt MO, Naumann R, Bareyre FM, Perocchi F, Mahad D, Merkler D, Lichtenthaler SF, Kerschensteiner M, Misgeld T (2023). Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions. Nat Metab. 2023 Jul 10. doi: 10.1038/s42255-023-00838-3. Epub ahead of print. PMID: 37430025.
Ziegler KA, Ahles A, Dueck A, Esfandyari D, Pichler P, Weber K, Kotschi S, Bartelt A, Sinicina I, Graw M, Leonhardt H, Weckbach LT, Massberg S, Schifferer M, Simons M, Hoeher L, Luo J, Ertürk A, Schiattarella GG, Sassi Y, Misgeld T Engelhardt S (2023). Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease. Science. 2023 Jul 21;381(6655):285-290. doi: 10.1126/science.abn6366. Epub 2023 Jul 20. PMID: 37471539.

2022

Düking T, Spieth L, Berghoff SA, Piepkorn L, Schmidke AM, Mitkovski M, Kannaiyan N, Hosang L, Scholz P, Shaib AH, Schneider LV, Hesse D, Ruhwedel T, Sun T, Linhoff L, Trevisiol A, Köhler S, Pastor AM, Misgeld T, Sereda M, Hassouna I, Rossner MJ, Odoardi F, Ischebeck T, de Hoz L, Hirrlinger J, Jahn O, Saher G (2022). Ketogenic diet uncovers differential metabolic plasticity of brain cells. Sci Adv. 2022 Sep 16;8(37):eabo7639. doi: 10.1126/sciadv.abo7639. Epub 2022 Sep 16. PMID: 36112685; PMCID: PMC9481126.
Herwerth M, Kenet S, Schifferer M, Winkler A, Weber M, Snaidero N, Wang M, Lohrberg M, Bennett JL, Stadelmann C, Hemmer B, Misgeld T (2022). A new form of axonal pathology in a spinal model of neuromyelitis optica. Brain. 2022 Feb 24:awac079. doi: 10.1093/brain/awac079. Epub ahead of print. PMID: 35202467.
121. Kalluri SR, Srivastava R, Kenet S, Tanti GK, Dornmair K, Bennett JL, Misgeld T, Hemmer B, Wyss MT, Herwerth M (2022). P2R Inhibitors Prevent Antibody-Mediated Complement Activation in an Animal Model of Neuromyelitis Optica : P2R Inhibitors Prevent Autoantibody Injury. Neurotherapeutics. 2022 Jul 12. doi: 10.1007/s13311-022-01269-w. Epub ahead of print. PMID: 35821382.
Kerschensteiner M, Misgeld T (2022). A less painful transfer of power. Neuron. 2022 Feb 16;110(4):559-561. doi: 10.1016/j.neuron.2022.01.021. PMID: 35176237.
Khalin I, Adarsh N, Schifferer M, Wehn A, Groschup B, Misgeld T, Klymchenko A, Plesnila N (2022). Size-Selective Transfer of Lipid Nanoparticle-Based Drug Carriers Across the Blood Brain Barrier Via Vascular Occlusions Following Traumatic Brain Injury. Small. 2022 Apr 5:e2200302. doi: 10.1002/smll.202200302. Epub ahead of print. PMID: 35384294.
Liesche-Starnecker F, Schifferer M, Schlegel J, Vollmuth Y, Rubbenstroth D, Delbridge C, Gempt J, Lorenzl S, Schnurbus L, Misgeld T, Rosati M, Beer M, Matiasek K, Wunderlich S, Finck T (2022). Hemorrhagic lesion with detection of infected endothelial cells in human bornavirus encephalitis. Acta Neuropathol. 2022 Jun 3:1–3. doi: 10.1007/s00401-022-02442-3. Epub ahead of print. PMID: 35657496; PMCID: PMC9164175.
Wang M, Misgeld T, Brill MS (2022). Neural labeling and manipulation by neonatal intraventricular viral injection in mic. STAR Protoc. 2022 Jan 10;3(1):101081. doi: 10.1016/j.xpro.2021.101081. PMID: 35059654; PMCID: PMC8760487.

2021

Eira J, Magalhães J, Macedo N, Pero ME, Misgeld T, Sousa MM, Bartolini F, Liz MA (2021). Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation. Front Cell Dev Biol. 2021 Nov 8;9:747699. doi: 10.3389/fcell.2021.747699. PMID: 34820375; PMCID: PMC8606651.
Engerer P, Petridou E, Williams PR, Suzuki SC, Yoshimatsu T, Portugues R, Misgeld T, Godinho L (2021). Notch-mediated re-specification of neuronal identity during central nervous system development. Curr Biol. 2021 Sep 7:S0960-9822(21)01185-4. doi: 10.1016/j.cub.2021.08.049. Epub ahead of print. PMID: 34534440.
Hiltensperger M, Beltrán E, Kant R, Tyystjärvi S, Lepennetier G, Domínguez Moreno H, Bauer IJ, Grassmann S, Jarosch S, Schober K, Buchholz VR, Kenet S, Gasperi C, Öllinger R, Rad R, Muschaweckh A, Sie C, Aly L, Knier B, Garg G, Afzali AM, Gerdes LA, Kümpfel T, Franzenburg S, Kawakami N, Hemmer B, Busch DH, Misgeld T, Dornmair K, Korn T (2021). Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity. Nat Immunol. 2021 Jun 7. doi: 10.1038/s41590-021-00948-8. Epub ahead of print. PMID: 34099917.
Jafari M, Schumacher AM, Snaidero N, Ullrich Gavilanes EM, Neziraj T, Kocsis-Jutka V, Engels D, Jürgens T, Wagner I, Weidinger JDF, Schmidt SS, Beltrán E, Hagan N, Woodworth L, Ofengeim D, Gans J, Wolf F, Kreutzfeldt M, Portugues R, Merkler D, Misgeld T, Kerschensteiner M (2021). Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation. Nat Neurosci. 2021 Jan 25. doi: 10.1038/s41593-020-00780-7. Epub ahead of print. PMID: 33495636.
Schifferer M, Snaidero N, Djannatian M, Kerschensteiner M, Misgeld T (2021). Niwaki Instead of Random Forests: Targeted Serial Sectioning Scanning Electron Microscopy With Reimaging Capabilities for Exploring Central Nervous System Cell Biology and Pathology. Front Neuroanat. 2021 Oct 13;15:732506. doi: 10.3389/fnana.2021.732506. PMID: 34720890; PMCID: PMC8548362.
Wang M, Kleele T, Xiao Y, Plucinska G, Avramopoulos P, Engelhardt S, Schwab MH, Kneussel M, Czopka T, Sherman DL, Brophy PJ, Misgeld T, Brill MS (2021). Completion of neuronal remodeling prompts myelination along developing motor axon branches. J Cell Biol. 2021 Apr 5;220(4):e201911114. doi: 10.1083/jcb.201911114. PMID: 33538762.

2020

Baumann T, Dunkel A, Schmid C, Schmitt S, Hiltensperger M, Lohr K, Laketa V, Donakonda S, Ahting U, Lorenz-Depiereux B, Heil JE, Schredelseker J, Simeoni L, Fecher C, Körber N, Bauer T, Hüser N, Hartmann D, Laschinger M, Eyerich K, Eyerich S, Anton M, Streeter M, Wang T, Schraven B, Spiegel D, Assaad F, Misgeld T, Zischka H, Murray PJ, Heine A, Heikenwälder M, Korn T, Dawid C, Hofmann T, Knolle PA, Höchst B (2020). Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal. Nat Immunol. 2020 May;21(5):555-566. doi: 10.1038/s41590-020-0666-9. Epub 2020 Apr 23.
Kislinger G, Gnägi H, Kerschensteiner M, Simons M, Misgeld T, Schifferer M (2020). Multiscale ATUM-FIB Microscopy Enables Targeted Ultrastructural Analysis at Isotropic Resolution. iScience. 2020;23(7):101290. doi:10.1016/j.isci.2020.101290 [published online ahead of print, 2020 Jun 20]
Kislinger G, Gnägi H, Kerschensteiner M, Simons M, Misgeld T (2020). ATUM-FIB microscopy for targeting and multiscale imaging of rare events in mouse cortex. STAR Protoc. 2020 Dec 16;1(3):100232. doi: 10.1016/j.xpro.2020.100232. PMID: 33377119; PMCID: PMC7757728.
LaClair KD, Zhou Q, Michaelsen M, Wefers B, Brill MS, Janjic A, Rathkolb B, Farny D, Cygan M, de Angelis MH, Wurst W, Neumann M, Enard W, Misgeld T, Arzberger T, Edbauer D (2020). Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS. Acta Neuropathol. 2020;10.1007/s00401-020-02176-0. doi:10.1007/s00401-020-02176-0 [published online ahead of print, 2020 Jun 19].
Masuda T, Amann L, Sankowski R, Staszewski O, Lenz M, D Errico P, Snaidero N, Costa Jordão MJ, Böttcher C, Kierdorf K, Jung S, Priller J, Misgeld T, Vlachos A, Luehmann MM, Knobeloch KP, Prinz M (2020). Novel Hexb-based tools for studying microglia in the CNS. Nat Immunol. 2020;21(7):802-815. doi:10.1038/s41590-020-0707-4
Mieskes F, Wehnekamp F, Plucińska G, Thong R, Misgeld T, Lamb DC (2020). Trajectory data of antero- and retrograde movement of mitochondria in living zebrafish larvae. Data Brief. 2020 Feb 13;29:105280. doi: 10.1016/j.dib.2020.105280. eCollection 2020 Apr.
Snaidero N, Schifferer M, Mezydlo A, Zalc B, Kerschensteiner M, Misgeld T (2020). Myelin replacement triggered by single-cell demyelination in mouse cortex. Nat Commun. 2020 Sep 29;11(1):4901. doi: 10.1038/s41467-020-18632-0. PMID: 32994410.
Ziak J, Weissova R, Jeřábková K, Janikova M, Maimon R, Petrasek T, Pukajova B, Kleisnerova M, Wang M, Brill MS, Kasparek P, Zhou X, Alvarez-Bolado G, Sedlacek R, Misgeld T, Stuchlik A, Perlson E, Balastik M (2020). CRMP2 mediates Sema3F-dependent axon pruning and dendritic spine remodeling. EMBO Rep. 2020 Jan 9:e48512. doi: 10.15252/embr.201948512. [Epub ahead of print]

2019

Djannatian M, Timmler S, Arends M, Luckner M, Weil MT, Alexopoulos I, Snaidero N, Schmid B, Misgeld T, Möbius W, Schifferer M, Peles E, Simons M (2019). Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS. Nat Commun. 2019 Oct 22;10(1):4794. doi: 10.1038/s41467-019-12789-z.
Fecher C, Trovò L, Müller SA, Snaidero N, Wettmarshausen J, Heink S, Ortiz O, Wagner I, Kühn R, Hartmann J, Karl RM, Konnerth A, Korn T, Wurst W, Merkler D, Lichtenthaler SF, Perocchi F, Misgeld T (2019). Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity. Nat Neurosci. 2019 Sep 9. doi: 10.1038/s41593-019-0479-z. [Epub ahead of print]
Schumacher AM, Misgeld T, Kerschensteiner M, Snaidero N (2019). Imaging the execution phase of neuroinflammatory disease models. Exp Neurol. 2019 May 29:112968. doi: 10.1016/j.expneurol.2019.112968. [Epub ahead of print]
Sigmund F, Pettinger S, Kube M, Schneider F, Schifferer M, Schneider S, Efremova MV, Pujol-Martí J, Aichler M, Walch A, Misgeld T, Dietz H, Westmeyer GG (2019). Iron-Sequestering Nanocompartments as Multiplexed Electron Microscopy Gene Reporters. ACS Nano. 2019 Jun 13. doi: 10.1021/acsnano.9b03140. [Epub ahead of print].
Wehnekamp F, Plucińska G, Thong R, Misgeld T, Lamb DC (2019). Nanoresolution real-time 3D orbital tracking for studying mitochondrial trafficking in vertebrate axons in vivo. Elife. 2019 Jun 10;8. pii: e46059. doi: 10.7554/eLife.46059.
Witte ME, Schumacher AM, Mahler CF, Bewersdorf JP, Lehmitz J, Scheiter A, Sánchez P, Williams PR, Griesbeck O, Naumann R, Misgeld T, Kerschensteiner M (2019). Calcium Influx through Plasma-Membrane Nanoruptures Drives Axon Degeneration in a Model of Multiple Sclerosis. Neuron. 2019 Jan 6. pii: S0896-6273(18)31123-1. doi: 10.1016/j.neuron.2018.12.023. [Epub ahead of print]

2018

Colombo A, Hsia HE, Wang M, Kuhn PH, Brill MS, Canevazzi P, Feederle R, Taveggia C, Misgeld T, Lichtenthaler SF (2018). Non-cell-autonomous function of DR6 in Schwann cell proliferation. EMBO J. 2018 Feb 19. pii: e97390. doi: 10.15252/embj.201797390. [Epub ahead of print]
Kiss A, Fischer I, Kleele T, Misgeld T, Propst F (2018). Neuronal Growth Cone Size-Dependent and -Independent Parameters of Microtubule Polymerization. Front Cell Neurosci. 2018 Jul 17;12:195. doi: 10.3389/fncel.2018.00195. eCollection 2018.

2017

Akassoglou K, Merlini M, Rafalski VA, Real R, Liang L, Jin Y, Dougherty SE, De Paola V, Linden DJ, Misgeld T, Zheng B(2017). In Vivo Imaging of CNS Injury and Disease. J Neurosci. 2017 Nov 8;37(45):10808-10816. doi: 10.1523/JNEUROSCI.1826-17.2017.
Engerer P, Suzuki SC, Yoshimatsu T, Chapouton P, Obeng N, Odermatt B, Williams PR, Misgeld T, Godinho L (2017). Uncoupling of neurogenesis and differentiation during retinal development. EMBO J. 2017 Mar 3. pii: e201694230. doi: 10.15252/embj.201694230. [Epub ahead of print]
Mazaheri F, Snaidero N, Kleinberger G, Madore C, Daria A, Werner G, Krasemann S, Capell A, Trümbach D, Wurst W, Brunner B, Bultmann S, Tahirovic S, Kerschensteiner M, Misgeld T, Butovsky O, Haass C (2017). TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury. EMBO Rep. 2017 May 8. pii: e201743922. doi: 10.15252/embr.201743922. [Epub ahead of print]
Misgeld T, Schwarz TL (2017). Mitostasis in Neurons: Maintaining Mitochondria in an Extended Cellular Architecture. Neuron. 2017 Nov 1;96(3):651-666. doi: 10.1016/j.neuron.2017.09.055.

2016

Bert B, Chmielewska J, Bergmann S, Busch M, Driever W, Finger-Baier K, Hößler J, Köhler A, Leich N, Misgeld T, Nöldner T, Reiher A, Schartl M, Seebach-Sproedt A, Thumberger T, Schönfelder G, Grune B (2016). Considerations for a European animal welfare standard to evaluate adverse phenotypes in teleost fish. EMBO J. 2016 Apr 22. pii: e201694448. [Epub ahead of print]
Brill MS, Kleele T, Ruschkies L, Wang M, Marahori NA, Reuter MS, Hausrat T, Weigand E, Fisher M, Ahles A, Engelhardt S, Bishop DL, Kneussel M, Misgeld T (2016). Branch-Specific Microtubule Destabilization Mediates Axon Branch Loss during Neuromuscular Synapse Elimination. Neuron. 2016 Oct 18. pii: S0896-6273(16)30654-7. doi: 10.1016/j.neuron.2016.09.049. [Epub ahead of print]
Engerer P, Fecher C, Misgeld T. (2016). Super-resolution microscopy writ large. Nat Biotechnol. 2016 Sep 8;34(9):928-30. doi: 10.1038/nbt.3669.
Fujikawa Y, Roma LP, Sobotta MC, Rose AJ, Diaz MB, Locatelli G, Breckwoldt MO, Misgeld T, Kerschensteiner M, Herzig S, Müller-Decker K, Dick TP (2016). Mouse redox histology using genetically encoded probes. Sci Signal. 2016 Mar 15;9(419):rs1. doi: 10.1126/scisignal.aad3895.
Heink S, Yogev N, Garbers C, Herwerth M, Aly L, Gasperi C, Husterer V, Croxford AL, Möller-Hackbarth K, Bartsch HS, Sotlar K, Krebs S, Regen T, Blum H, Hemmer B, Misgeld T, Wunderlich TF, Hidalgo J, Oukka M, Rose-John S, Schmidt-Supprian M, Waisman A, Korn T (2016). Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells. Nat Immunol. 2016 Nov 28. doi: 10.1038/ni.3632. [Epub ahead of print]
Herwerth M, Kalluri SR, Srivastava R, Kleele T, Kenet S, Illes Z, Merkler D, Bennett JL, Misgeld T, Hemmer B (2016). In vivo imaging reveals rapid astrocyte depletion and axon damage in a model of neuromyelitis optica-related pathology. Ann Neurol. 2016 Mar 6. doi: 10.1002/ana.24630. [Epub ahead of print]
Plucińska G, Misgeld T (2016). Imaging of neuronal mitochondria in situ. Curr Opin Neurobiol. 2016 Jul 22;39:152-163. doi: 10.1016/j.conb.2016.06.006. [Epub ahead of print]
Romanelli E, Merkler D, Mezydlo A, Weil MT, Weber MS, Nikić I, Potz S, Meinl E, Matznick FE, Kreutzfeldt M, Ghanem A, Conzelmann KK, Metz I, Brück W, Routh M, Simons M, Bishop D, Misgeld T, Kerschensteiner M (2016). Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model. Nat Commun. 2016 Nov 16;7:13275. doi: 10.1038/ncomms13275ub ahead of print]

2015

Breckwoldt MO, Wittmann C, Misgeld T, Kerschensteiner M, Grabher C (2015). Redox imaging using genetically encoded redox indicators in zebrafish and mice. Biol Chem. 2015 Jan 29. pii: /j/bchm.just-accepted/hsz-2014-0294/hsz-2014-0294.xml. doi: 10.1515/hsz-2014-0294. [Epub ahead of print]
Held K, Bhonsle-Deeng L, Siewert K, Sato W, Beltrán E, Schmidt S, Rühl G, Ng JK, Engerer P, Moser M, Klinkert WE, Babbe H, Misgeld T, Wekerle H, Laplaud DA, Hohlfeld R, Dornmair K (2015). αβ T-cell receptors from multiple sclerosis brain lesions show MAIT cell-related features. Neurol Neuroimmunol Neuroinflamm. 2015 May 7;2(4):e107. doi: 10.1212/NXI.0000000000000107. eCollection 2015.

2014

Bishop D, Nikic I, Kerschensteiner M, Misgeld T (2014). The use of a laser for correlating light and electron microscopic images in thick tissue specimens. Methods Cell Biol. 2014;124:323-37. doi: 10.1016/B978-0-12-801075-4.00015-X
Breckwoldt MO, Pfister FM, Bradley PM, Marinković P, Williams PR, Brill MS, Plomer B, Schmalz A, St Clair DK, Naumann R, Griesbeck O, Schwarzländer M, Godinho L, Bareyre FM, Dick TP, Kerschensteiner M, Misgeld T (2014). Multiparametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo. Nat Med. 2014 Apr 20. doi: 10.1038/nm.3520. [Epub ahead of print]
Hartmann J, Karl RM, Alexander RP, Adelsberger H, Brill MS, Rühlmann C, Ansel A, Sakimura K, Baba Y, Kurosaki T, Misgeld T, Konnerth A (2014). STIM1 Controls Neuronal Ca(2+) Signaling, mGluR1-Dependent Synaptic Transmission, and Cerebellar Motor Behavior. Neuron. 2014 May 7;82(3):635-44. doi: 10.1016/j.neuron.2014.03.027.
Kleele T, Marinković P, Williams PR, Stern S, Weigand EE, Engerer P, Naumann R, Hartmann J, Karl RM, Bradke F, Bishop D, Herms J, Konnerth A, Kerschensteiner M, Godinho L, Misgeld T (2014). An assay to image neuronal microtubule dynamics in mice. Nat Commun. 2014 Sep 12;5:4827. doi: 10.1038/ncomms5827
Mar FM, Simões AR, Leite S, Morgado MM, Santos TE, Rodrigo IS, Teixeira CA, Misgeld T, Sousa MM (2014). CNS axons globally increase axonal transport after peripheral conditioning. J Neurosci. 2014 Apr 23;34(17):5965-70. doi: 10.1523/JNEUROSCI.4680-13.2014.
Paquet D, Plucińska G, Misgeld T (2014). In vivo imaging of mitochondria in intact zebrafish larvae. Methods Enzymol. 2014;547:151-64. doi: 10.1016/B978-0-12-801415-8.00009-6.
Simons M, Misgeld T, Kerschensteiner M (2014). A unified cell biological perspective on axon-myelin injury. J Cell Biol. 2014 Aug 4;206(3):335-345
Sorbara CD, Wagner NE, Ladwig A, Nikić I, Merkler D, Kleele T, Marinković P, Naumann R, Godinho L, Bareyre FM, Bishop D, Misgeld T, Kerschensteiner M (2014). Pervasive Axonal Transport Deficits in Multiple Sclerosis Models. Neuron. 2014 Nov 25. pii: S0896-6273(14)01006-X. doi: 10.1016/j.neuron.2014.11.006. [Epub ahead of print]
Wang K, Milkie DE, Saxena A, Engerer P, Misgeld T, Bronner ME, Mumm J, Betzig E (2014). Rapid adaptive optical recovery of optimal resolution over large volumes. Nat Methods. 2014 Apr 13. doi: 10.1038/nmeth.2925. [Epub ahead of print]
Williams PR, Marincu BN, Sorbara CD, Mahler CF, Schumacher AM, Griesbeck O, Kerschensteiner M, Misgeld T (2014). A recoverable state of axon injury persists for hours after spinal cord contusion in vivo. Nat Commun. 2014 Dec 16;5:5683. doi: 10.1038/ncomms6683.

2013

Brill MS, Marinković P, Misgeld T (2013). Sequential Photo-bleaching to Delineate Single Schwann Cells at the Neuromuscular Junction. J Vis Exp. 11(71) (2013)
Kreutzfeldt M, Bergthaler A, Fernandez M, Brück W, Steinbach K, Vorm M, Coras R, Blümcke I, Bonilla WV, Fleige A, Forman R, Müller W, Becher B, Misgeld T, Kerschensteiner M, Pinschewer DD, Merkler D (2013). Neuroprotective intervention by interferon-γ blockade prevents CD8+ T cell-mediated dendrite and synapse loss. J Exp Med. 2013 Sep 2. [Epub ahead of print]
Misgeld T, Lichtenthaler SF, Dichgans M (2013). Between new genetic discoveries and large randomized trials-neurological research in the era of systems medicine. EMBO Rep. 2013 May 14. doi: 10.1038/embor.2013.70. [Epub ahead of print]
84. Romanelli E, Sorbara CD, Nikić I, Dagkalis A, Misgeld T, Kerschensteiner M (2013). Cellular, subcellular and functional in vivo labeling of the spinal cord using vital dyes. Nat Protoc. 8(3):481-90 (2013)

2012

Misgeld, Thomas

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