Höglinger, Günter
2024
- Bernhardt AM, Nemati M, Boros FA, Hopfner F, Levin J, Mollenhauer B, Winkler J, Zerr I, Zunke F, Höglinger G. α-Synuclein Seed Amplification Assays from Blood-Based Extracellular Vesicles in Parkinson's Disease: An Evaluation of the Evidence. Mov Disord. 2024 Jul 11. doi: 10.1002/mds.29923. Epub ahead of print. PMID: 38989741.
- Biechele G, Rauchmann BS, Janowitz D, Buerger K, Franzmeier N, Weidinger E, Guersel S, Schuster S, Finze A, Harris S, Lindner S, Albert NL, Wetzel C, Rupprecht R, Rominger A, Palleis C, Katzdobler S, Burow L, Kurz C, Zaganjori M, Trappmann LK, Goldhardt O, Grimmer T, Haeckert J, Keeser D, Stoecklein S, Morenas-Rodriguez E, Bartenstein P, Levin J, Höglinger GU, Simons M, Perneczky R, Brendel M. Associations between sex, body mass index and the individual microglial response in Alzheimer's disease. J Neuroinflammation. 2024 Jan 23;21(1):30. doi:10.1186/s12974-024-03020-y. PMID: 38263017; PMCID: PMC10804830.
- Bischof GN, Brendel M, Barthel H, Theis H, Barbe M, Bartenstein P, Claasen J, Danek A, Höglinger G, Levin J, Marek K, Neumaier B, Palleis C, Patt M, Rullmann M, Saur D, Schroeter ML, Seibyl J, Song M, Stephens A, Sabri O, Drzezga A, van Eimeren T; German Imaging Initiative for Tauopathies. Improved Tau PET SUVR Quantification in 4-Repeat Tau Phenotypes with [18F]PI-2620. J Nucl Med. 2024 Apr 4:jnumed.123.265930. doi: 10.2967/jnumed.123.265930. Epub ahead of print. PMID: 38575191.
Brendel M, Guedj E, Yakushev I, Morbelli S, Höglinger GU, Tolboom N, Verger A, Albert NL, Cecchin D, Fernandez PA, Fraioli F, Traub-Weidinger T, Van Weehaeghe D, Barthel H. Neuroimaging biomarkers in the biological definition of Parkinson's disease and dementia with Lewy bodies - EANM position on current state, unmet needs and future perspectives. Eur J Nucl Med Mol Imaging. 2024 Jun 22. doi: 10.1007/s00259-024-06803-w. Epub ahead of print. PMID: 38907856.
Buchert R, Huppertz HJ, Wegner F, Berding G, Brendel M, Apostolova I, Buhmann C, Poetter-Nerger M, Dierks A, Katzdobler S, Klietz M, Levin J, Mahmoudi N, Rinscheid A, Quattrone A, Rogozinski S, Rumpf JJ, Schneider C, Stoecklein S, Spetsieris PG, Eidelberg D, Sabri O, Barthel H, Wattjes MP, Höglinger G; Alzheimer’s Disease Neuroimaging Initiative. Added value of FDG-PET for detection of progressive supranuclear palsy. J Neurol Neurosurg Psychiatry. 2024 Aug 8:jnnp-2024-333590. doi: 10.1136/jnnp-2024-333590. Epub ahead of print. PMID: 39107038.
Chatterjee M, Özdemir S, Fritz C, Möbius W, Kleineidam L, Mandelkow E, Biernat J, Doğdu C, Peters O, Cosma NC, Wang X, Schneider LS, Priller J, Spruth E, Kühn AA, Krause P, Klockgether T, Vogt IR, Kimmich O, Spottke A, Hoffmann DC, Fliessbach K, Miklitz C, McCormick C, Weydt P, Falkenburger B, Brandt M, Guenther R, Dinter E, Wiltfang J, Hansen N, Bähr M, Zerr I, Flöel A, Nestor PJ, Düzel E, Glanz W, Incesoy E, Bürger K, Janowitz D, Perneczky R, Rauchmann BS, Hopfner F, Wagemann O, Levin J, Teipel S, Kilimann I, Goerss D, Prudlo J, Gasser T, Brockmann K, Mengel D, Zimmermann M, Synofzik M, Wilke C, Selma-González J, Turon-Sans J, Santos-Santos MA, Alcolea D, Rubio-Guerra S, Fortea J, Carbayo Á, Lleó A, Rojas-García R, Illán-Gala I, Wagner M, Frommann I, Roeske S, Bertram L, Heneka MT, Brosseron F, Ramirez A, Schmid M, Beschorner R, Halle A, Herms J, Neumann M, Barthélemy NR, Bateman RJ, Rizzu P, Heutink P, Dols-Icardo O, Höglinger G, Hermann A, Schneider A. Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS. Nat Med. 2024 Jun;30(6):1771-1783. doi: 10.1038/s41591-024-02937-4. Epub 2024 Jun 18. PMID: 38890531; PMCID: PMC11186765.
- Chopra A, Lang AE, Höglinger G, Outeiro TF. Towards a biological diagnosis of PD. Parkinsonism Relat Disord. 2024 Mar 6:106078. doi: 10.1016/j.parkreldis.2024.106078. Epub ahead of print. PMID: 38472075.
- Costa MFD, Rösler TW, Höglinger GU. Exploring the neuroprotective potential of Nrf2-pathway activators against annonacin toxicity. Sci Rep. 2024 Aug 29;14(1):20123. doi: 10.1038/s41598-024-70837-1. PMID: 39209951; PMCID: PMC11362529.
Dilcher R, Wall S, Groß M, Katzdobler S, Wagemann O, Palleis C, Weidinger E, Fietzek U, Bernhardt A, Kurz C, Ferschmann C, Scheifele M, Zaganjori M, Gnörich J, Bürger K, Janowitz D, Rauchmann BS, Stöcklein S, Bartenstein P, Villemagne V, Seibyl J, Sabri O, Barthel H, Perneczky R, Schöberl F, Zwergal A, Höglinger GU, Levin J, Franzmeier N, Brendel M. Combining cerebrospinal fluid and PI-2620 tau-PET for biomarker-based stratification of Alzheimer's disease and 4R-tauopathies. Alzheimers Dement. 2024 Sep 12. doi: 10.1002/alz.14185. Epub ahead of print. PMID: 39263969.
- Farrell K, Humphrey J, Chang T, Zhao Y, Leung YY, Kuksa PP, Patil V, Lee WP, Kuzma AB, Valladares O, Cantwell LB, Wang H, Ravi A, De Sanctis C, Han N, Christie TD, Afzal R, Kandoi S, Whitney K, Krassner MM, Ressler H, Kim S, Dangoor D, Iida MA, Casella A, Walker RH, Nirenberg MJ, Renton AE, Babrowicz B, Coppola G, Raj T, Höglinger GU, Müller U, Golbe LI, Morris HR, Hardy J, Revesz T, Warner TT, Jaunmuktane Z, Mok KY, Rademakers R, Dickson DW, Ross OA, Wang LS, Goate A, Schellenberg G, Geschwind DH; PSP Genetics Study Group [i.a. Herms J]; Crary JF, Naj A. Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes. Nat Commun. 2024 Sep 9;15(1):7880. doi: 10.1038/s41467-024-52025-x. PMID: 39251599; PMCID: PMC11385559.
- Ferschmann C, Messerschmidt K, Gnörich J, Barthel H, Marek K, Palleis C, Katzdobler S, Stockbauer A, Fietzek U, Finze A, Biechele G, Rumpf JJ, Saur D, Schroeter ML, Rullmann M, Beyer L, Eckenweber F, Wall S, Schildan A, Patt M, Stephens A, Classen J, Bartenstein P, Seibyl J, Franzmeier N, Levin J, Höglinger GU, Sabri O, Brendel M, Scheifele M; German Imaging Initiative for Tauopathies (GII4T). Tau accumulation is associated with dopamine deficiency in vivo in four-repeat tauopathies. Eur J Nucl Med Mol Imaging. 2024 Feb 17. doi: 10.1007/s00259-024-06637-6. Epub ahead of print. PMID: 38366196.
- Germani M, Rebollo Mesa I, Buchanan TJ, De Bruyn S, Gasalla T, Van Tricht HLG, Ewen C, Golbe LI, Boxer A, Höglinger G. Combined Assessment of Function and Survival to Demonstrate the Effect of Treatment on Progressive Supranuclear Palsy. Mov Disord. 2024 Oct 29. doi: 10.1002/mds.30027. Epub ahead of print. PMID: 39470015.
- Gewily M, Plan EL, Yousefi E, König F, Posch M, Hopfner F, Höglinger G, Karlsson MO. Quantitative Comparisons of Progressive Supranuclear Palsy Rating Scale Versions Using Item Response Theory. Mov Disord. 2024 Aug 29. doi: 10.1002/mds.30001. Epub ahead of print. PMID: 39206961.
- Graessner H, Reinhard C, Bäumer T, Baumgärtner A, Brockmann K, Brüggemann N, Bültmann E, Erdmann J, Heise K, Höglinger G, Hüning I, Kaiser FJ, Klein C, Klopstock T, Krägeloh-Mann I, Kraemer M, Luedtke K, Mücke M, Musacchio T, Nadke A, Osmanovic A, Ritter G, Röse K, Schippers C, Schöls L, Schüle R, Schulz JB, Sproß J, Stasch E, Wunderlich G, Münchau A. Recommendations for optimal interdisciplinary management and healthcare settings for patients with rare neurological diseases. Orphanet J Rare Dis. 2024 Feb 13;19(1):62. doi: 10.1186/s13023-024-03023-1. PMID: 38347616; PMCID: PMC10863275.
- Hopfner F, Höglinger G; German Parkinson’s Guidelines Group [i.a. Levin J, Lingor P]; Trenkwalder C. Definition and diagnosis of Parkinson's disease: guideline "Parkinson's disease" of the German Society of Neurology. J Neurol. 2024 Sep 19. doi: 10.1007/s00415-024-12687-5. Epub ahead of print. PMID: 39297986.
- Höglinger G; German Parkinson’s Guidelines Committee [i.a. Levin J, Lingor P]; Trenkwalder C. Diagnosis and treatment of Parkinson´s disease (guideline of the German Society for Neurology). Neurol Res Pract. 2024 Jun 6;6(1):30. doi: 10.1186/s42466-024-00325-4. PMID: 38845028; PMCID: PMC11157782.
- Höglinger G, Jost WH. Every generation got its own disease. J Neural Transm (Vienna). 2024 May 2. doi: 10.1007/s00702-024-02767-1. Epub ahead of print. PMID: 38693462.
- Höglinger GU, Adler CH, Berg D, Klein C, Outeiro TF, Poewe W, Postuma R, Stoessl AJ, Lang AE. A biological classification of Parkinson's disease: the SynNeurGe research diagnostic criteria. Lancet Neurol. 2024 Feb;23(2):191-204. doi: 10.1016/S1474-4422(23)00404-0. Erratum in: Lancet Neurol. 2024 Mar;23(3):e7. PMID: 38267191.
- Höglinger GU, Boxer AL, Lang AE. Clinical versus biomarker-based diagnosis of neurocognitive disorders. Lancet Neurol. 2024 Aug;23(8):765-766. doi: 10.1016/S1474-4422(24)00274-6. PMID: 39030034.
Höglinger GU, Lang AE. The why and how of the SynNerGe criteria of Parkinson´s disease. J Neural Transm (Vienna). 2024 Jun 25. doi: 10.1007/s00702-024-02797-9. Epub ahead of print. PMID: 38916622.
- Höllerhage M, Becktepe J, Classen J, Deuschl G, Ebersbach G, Hopfner F, Lingor P, Löhle M, Maaß S, Pötter-Nerger M, Odin P, Woitalla D; German Parkinson’s Guidelines Group [i.a. Levin J]; Trenkwalder C, Höglinger GU. Pharmacotherapy of motor symptoms in early and mid-stage Parkinson's disease: guideline "Parkinson's disease" of the German Society of Neurology. J Neurol. 2024 Aug 29. doi: 10.1007/s00415-024-12632-6. Epub ahead of print. PMID: 39207521.
- Jensen I, Heine J, Ruf VC, Compta Y, Porcel LM, Troakes C, Vamanu A, Downes S, Irwin D, Cohen J, Lee EB, Nilsson C, Englund E, Nemati M, Katzdobler S, Levin J, Pantelyat A, Seemiller J, Berger S, van Swieten J, Dopper E, Rozenmuller A, Kovacs GG, Bendahan N, Lang AE, Herms J, Höglinger G, Hopfner F. Impact of Magnetic Resonance Imaging Markers on the Diagnostic Performance of the International Parkinson and Movement Disorder Society Multiple System Atrophy Criteria. Mov Disord. 2024 Jun 7. doi: 10.1002/mds.29879. Epub ahead of print. PMID: 38847384.
- Jensen I, Stiel S, Bebermeier S, Schrag A, Greten S, Doll-Lee J, Wegner F, Ye L, Heine J, Krey L, Höllerhage M, Süß P, Winkler J, Berg D, Paschen S, Tönges L, Gruber D, Gandor F, Jost WH, Kühn AA, Claus I, Warnecke T, Pedrosa DJ, Eggers C, Trenkwalder C, Classen J, Schwarz J, Pötter-Nerger M, Kassubek J, Schnitzler A, Höglinger GU, Klietz M. A Short Progressive Supranuclear Palsy Quality of Life Scale. Mov Disord. 2024 Jul 26. doi: 10.1002/mds.29936. Epub ahead of print. PMID: 39056204.
- Katzdobler S, Nübling G, Klietz M, Fietzek UM, Palleis C, Bernhardt AM, Wegner F, Huber M, Rogozinski S, Schneider LS, Spruth EJ, Beyle A, Vogt IR, Brandt M, Hansen N, Glanz W, Brockmann K, Spottke A, Hoffmann DC, Peters O, Priller J, Wiltfang J, Düzel E, Schneider A, Falkenburger B, Klockgether T, Gasser T, Nuscher B, Haass C, Höglinger G, Levin J. GFAP and NfL as fluid biomarkers for clinical disease severity and disease progression in multiple system atrophy (MSA). J Neurol. 2024 Sep 10. doi: 10.1007/s00415-024-12647-z. Epub ahead of print. PMID: 39254698.
- Levin J, Baiardi S, Quadalti C, Rossi M, Mammana A, Vöglein J, Bernhardt A, Perrin RJ, Jucker M, Preische O, Hofmann A, Höglinger GU, Cairns NJ, Franklin EE, Chrem P, Cruchaga C, Berman SB, Chhatwal JP, Daniels A, Day GS, Ryan NS, Goate AM, Gordon BA, Huey ED, Ibanez L, Karch CM, Lee JH, Llibre-Guerra J, Lopera F, Masters CL, Morris JC, Noble JM, Renton AE, Roh JH, Frosch MP, Keene CD, McLean C, Sanchez-Valle R, Schofield PR, Supnet-Bell C, Xiong C, Giese A, Hansson O, Bateman RJ, McDade E; Dominantly Inherited Alzheimer Network; Parchi P. α-Synuclein seed amplification assay detects Lewy body co-pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden. Alzheimers Dement. 2024 Apr 26. doi: 10.1002/alz.13818. Epub ahead of print. PMID: 38666355.
Mahmoudi R, Greten S, Veith Sanches L, Krey L, Ulaganathan S, Höglinger GU, Heck J, Wegner F, Klietz M. Impact of the Anticholinergic Burden on Disease-Specific Symptoms in Parkinsonian Syndromes. Brain Sci. 2024 Aug 11;14(8):805. doi: 10.3390/brainsci14080805. PMID: 39199497; PMCID: PMC11352570.
- Malpetti M, Roemer SN, Harris S, Gross M, Gnörich J, Stephens A, Dewenter A, Steward A, Biel D, Dehsarvi A, Wagner F, Müller A, Koglin N, Weidinger E, Palleis C, Katzdobler S, Rupprecht R, Perneczky R, Rauchmann BS, Levin J, Höglinger GU, Brendel M, Franzmeier N. Neuroinflammation Parallels 18F-PI-2620 Positron Emission Tomography Patterns in Primary 4-Repeat Tauopathies. Mov Disord. 2024 Jul 18. doi: 10.1002/mds.29924. Epub ahead of print. PMID: 39022835.
Meindl M, Zatcepin A, Gnörich J, Scheifele M, Zaganjori M, Groß M, Lindner S, Schaefer R, Simmet M, Roemer S, Katzdobler S, Levin J, Höglinger G, Bischof AC, Barthel H, Sabri O, Bartenstein P, Saller T, Franzmeier N, Ziegler S, Brendel M. Assessment of [18F]PI-2620 Tau-PET Quantification via Non-Invasive Automatized Image Derived Input Function. Eur J Nucl Med Mol Imaging. 2024 May 8. doi: 10.1007/s00259-024-06741-7. Epub ahead of print. PMID: 38717592.
- Möhn N, Grote-Levi L, Wattjes MP, Bonifacius A, Holzwart D, Hopfner F, Nay S, Tischer-Zimmermann S, Saßmann ML, Schwenkenbecher P, Sühs KW, Mahmoudi N, Warnke C, Zimmermann J, Hagin D, Goudeva L, Blasczyk R, Koch A, Maecker-Kolhoff B, Eiz-Vesper B, Höglinger G, Skripuletz T. Directly Isolated Allogeneic Virus-Specific T Cells in Progressive Multifocal Leukoencephalopathy. JAMA Neurol. 2024 Oct 7:e243324. doi: 10.1001/jamaneurol.2024.3324. Epub ahead of print. PMID: 39374035; PMCID: PMC11459361.
- Nay S, Möhn N, Grote-Levi L, Bonifacius A, Saßmann ML, Karacondi K, Tischer-Zimmermann S, Pöter H, Mahmoudi N, Wattjes MP, Maecker-Kolhoff B, Höglinger G, Eiz-Vesper B, Skripuletz T. Combined treatment with allogeneic Epstein-Barr- and human polyomavirus 1 specific T-cells in progressive multifocal leukoencephalopathy and EBV infection: a case report. Ther Adv Neurol Disord. 2024 May 28;17:17562864241253917. doi: 10.1177/17562864241253917. PMID: 38813521; PMCID: PMC11135084.
- Palleis C, Franzmeier N, Weidinger E, Bernhardt AM, Katzdobler S, Wall S, Ferschmann C, Harris S, Schmitt J, Schuster S, Gnörich J, Finze A, Biechele G, Lindner S, Albert NL, Bartenstein P, Sabri O, Barthel H, Rupprecht R, Nuscher B, Stephens AW, Rauchmann BS, Perneczky R, Haass C, Brendel M, Levin J, Höglinger GU. Association of Neurofilament Light Chain, [18F]PI-2620 Tau-PET, TSPO-PET, and Clinical Progression in Patients With β-Amyloid-Negative CBS. Neurology. 2024 Jan 9;102(1):e207901. doi: 10.1212/WNL.0000000000207901. Epub 2023 Dec 14. PMID: 38165362.
- Pötter-Nerger M, Löhle M, Höglinger G; German Parkinson‘s Guideline Group. Akinetic crisis and withdrawal syndromes: guideline "Parkinson's disease" of the German Society of Neurology. J Neurol. 2024 Aug 27. doi: 10.1007/s00415-024-12649-x. Epub ahead of print. PMID: 39192030.
- Quattrone A, Franzmeier N, Huppertz HJ, Klietz M, Roemer SN, Boxer AL, Levin J, Höglinger GU; AL‐108‐231 Investigators, the Tauros MRI Investigators, the PASSPORT Study Group, the DESCRIBE‐PSP Group. Magnetic Resonance Imaging Measures to Track Atrophy Progression in Progressive Supranuclear Palsy in Clinical Trials. Mov Disord. 2024 Jun 2. doi: 10.1002/mds.29866. Epub ahead of print. PMID: 38825840.
- Roemer SN, Brendel M, Gnoerich J, Malpetti M, Zaganjori M, Quattrone A, Gross M, Steward A, Dewenter A, Wagner F, Dehsarvi A, Ferschmann C, Wall S, Palleis C, Rauchmann BS, Katzdobler S, Jaeck A, Stockbauer A, Fietzek UM, Bernhardt AM, Weidinger E, Zwergal A, Stoecklein S, Perneczky R, Barthel H, Sabri O, Levin J, Hoeglinger GU, Franzmeier N. Subcortical tau is linked to hypoperfusion in connected cortical regions in 4-repeat tauopathies. Brain. 2024 Jun 6:awae174. doi: 10.1093/brain/awae174. Epub ahead of print. PMID: 38842726.
- Schoenmakers DH, van den Berg S, Timmers L, Adang LA, Bäumer T, Bosch A, van de Casteele M, Datema MR, Dekker H, Donnelly C, Driessens MHE, Graessner H, Greger V, Haddad T, Höglinger GU, van den Hout H, Jonker C, Langeveld M, Lambert LJ, Neacy E, Nieuwland M, Klockgether T, van der Knaap MS, Papadopoulou A, Plueschke K, van Rijn S, Rosenberg N, Saunier-Vivar EF, Dos Santos Vieira B, Hollak CEM, Goettsch WG, Wolf NI. Framework for Multistakeholder Patient Registries in the Field of Rare Diseases: Focus on Neurogenetic Diseases. Neurology. 2024 Sep 24;103(6):e209743. doi: 10.1212/WNL.0000000000209743. Epub 2024 Aug 22. PMID: 39173102.
- Schönecker S, Martinez-Murcia FJ, Denecke J, Franzmeier N, Danek A, Wagemann O, Prix C, Wlasich E, Vöglein J, Loosli SV, Brauer A, Górriz Sáez JM, Bouzigues A, Russell LL, Foster PH, Ferry-Bolder E, van Swieten JC, Jiskoot LC, Seelaar H, Sanchez-Valle R, Laforce R Jr, Graff C, Galimberti D, Vandenberghe R, de Mendonça A, Tiraboschi P, Santana I, Gerhard A, Sorbi S, Otto M, Pasquier F, Ducharme S, Butler C, Le Ber I, Finger E, Tartaglia MC, Masellis M, Rowe JB, Synofzik M, Moreno F, Borroni B, Rohrer JD; Genetic Frontotemporal Dementia Initiative (GENFI); Priller J, Höglinger GU, Levin J. Frequency and Longitudinal Course of Behavioral and Neuropsychiatric Symptoms in Participants With Genetic Frontotemporal Dementia. Neurology. 2024 Oct 22;103(8):e209569. doi: 10.1212/WNL.0000000000209569. Epub 2024 Sep 16. PMID: 39284109; PMCID: PMC11399068.
- Veith Sanches L, Greten S, Doll-Lee J, Rogozinski SM, Heine J, Krey L, Ulaganathan S, Jensen I, Höllerhage M, Sani SS, Höglinger GU, Wegner F, Klietz M. SEND-PD in Parkinsonian Syndromes: Results of a Monocentric Cross-Sectional Study. Neuropsychiatr Dis Treat. 2024 Oct 1;20:1849-1859. doi: 10.2147/NDT.S474584. PMID: 39372876; PMCID: PMC11453152.
- Walter U, Loewenbrück KF, Dodel R, Storch A, Trenkwalder C, Höglinger G; German Parkinson Guideline Group. Systematic review-based guideline "Parkinson's disease" of the German Society of Neurology: diagnostic use of transcranial sonography. J Neurol. 2024 Jul 4. doi: 10.1007/s00415-024-12502-1. Epub ahead of print. PMID: 38963440.
- Wuehr M, Peto D, Fietzek UM, Katzdobler S, Nübling G, Zaganjori M, Brendel M, Levin J, Höglinger GU, Zwergal A. Low-intensity vestibular noise stimulation improves postural symptoms in progressive supranuclear palsy. J Neurol. 2024 May 9. doi: 10.1007/s00415-024-12419-9. Epub ahead of print. PMID: 38722328.
- Ye L, Greten S, Wegner F, Doll-Lee J, Krey L, Heine J, Gandor F, Vogel A, Berger L, Gruber D, Levin J, Katzdobler S, Peters O, Dashti E, Priller J, Spruth EJ, Kühn AA, Krause P, Spottke A, Schneider A, Beyle A, Kimmich O, Donix M, Haussmann R, Brandt M, Dinter E, Wiltfang J, Schott BH, Zerr I, Bähr M, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Weidinger E, Düzel E, Glanz W, Teipel S, Kilimann I, Wurster I, Brockmann K, Hoffmann DC, Klockgether T, Krause O, Heck J; PROMESA study group; Höglinger GU, Klietz M. The comorbidity profiles and medication issues of patients with multiple system atrophy: a systematic cross-sectional analysis. J Neurol. 2024 Feb 14. doi: 10.1007/s00415-024-12207-5. Epub ahead of print. PMID: 38353748.
- Ye L, Sani SS, Veith Sanches L, Krey LFM, Wegner F, Höllerhage M, Schrader C, Höglinger G, Klietz M. Acute Levodopa Challenge in Atypical Parkinsonism: Comprehensive Analysis of Individual Motor Responses. Brain Sci. 2024 Sep 29;14(10):991. doi: 10.3390/brainsci14100991. PMID: 39452005; PMCID: PMC11506334.
- Yousefi E, Gewily M, König F, Höglinger G, Hopfner F, Karlsson MO, Ristl R, Zehetmayer S, Posch M. Efficiency of multivariate tests in trials in progressive supranuclear palsy. Sci Rep. 2024 Oct 26;14(1):25581. doi: 10.1038/s41598-024-76668-4. PMID: 39462124; PMCID: PMC11514033.
Zatcepin A, Gnörich J, Rauchmann BS, Bartos LM, Wagner S, Franzmeier N, Malpetti M, Xiang X, Shi Y, Parhizkar S, Grosch M, Wind-Mark K, Kunte ST, Beyer L, Meyer C, Brösamle D, Wendeln AC, Osei-Sarpong C, Heindl S, Liesz A, Stoecklein S, Biechele G, Finze A, Eckenweber F, Lindner S, Rominger A, Bartenstein P, Willem M, Tahirovic S, Herms J, Buerger K, Simons M, Haass C, Rupprecht R, Riemenschneider MJ, Albert NL, Beyer M, Neher JJ, Paeger L, Levin J, Höglinger GU, Perneczky R, Ziegler SI, Brendel M. Regional desynchronization of microglial activity is associated with cognitive decline in Alzheimer's disease. Mol Neurodegener. 2024 Sep 5;19(1):64. doi: 10.1186/s13024-024-00752-6. PMID: 39238030; PMCID: PMC11375924.
2023
- El Bouhaddani S, Höllerhage M, Uh HW, Moebius C, Bickle M, Höglinger G, Houwing-Duistermaat J. Statistical integration of multi-omics and drug screening data from cell lines. PLoS Comput Biol. 2024 Jan 31;20(1):e1011809. doi: 10.1371/journal.pcbi.1011809. PMID: 38295113; PMCID: PMC10878536.
- Greten S, Wegner F, Jensen I, Krey L, Rogozinski S, Fehring M, Heine J, Doll-Lee J, Pötter-Nerger M, Zeitzschel M, Hagena K, Pedrosa DJ, Eggers C, Bürk K, Trenkwalder C, Claus I, Warnecke T, Süß P, Winkler J, Gruber D, Gandor F, Berg D, Paschen S, Classen J, Pinkhardt EH, Kassubek J, Jost WH, Tönges L, Kühn AA, Schwarz J, Peters O, Dashti E, Priller J, Spruth EJ, Krause P, Spottke A, Schneider A, Beyle A, Kimmich O, Donix M, Haussmann R, Brandt M, Dinter E, Wiltfang J, Schott BH, Zerr I, Bähr M, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Weidinger E, Levin J, Katzdobler S, Düzel E, Glanz W, Teipel S, Kilimann I, Prudlo J, Gasser T, Brockmann K, Hoffmann DC, Klockgether T, Krause O, Heck J, Höglinger GU, Klietz M (2023). The comorbidity and co-medication profile of patients with progressive supranuclear palsy. J Neurol. 2023 Oct 6. doi: 10.1007/s00415-023-12006-4. Epub ahead of print. PMID: 37803149.
- Stockbauer A, Beyer L, Huber M, Kreuzer A, Palleis C, Katzdobler S, Rauchmann BS, Morbelli S, Chincarini A, Bruffaerts R, Vandenberghe R, Kramberger MG, Trost M, Garibotto V, Nicastro N, Lathuilière A, Lemstra AW, van Berckel BNM, Pilotto A, Padovani A, Ochoa-Figueroa MA, Davidsson A, Camacho V, Peira E, Bauckneht M, Pardini M, Sambuceti G, Aarsland D, Nobili F, Gross M, Vöglein J, Perneczky R, Pogarell O, Buerger K, Franzmeier N, Danek A, Levin J, Höglinger GU, Bartenstein P, Cumming P, Rominger A, Brendel M (2023). Metabolic network alterations as a supportive biomarker in dementia with Lewy bodies with preserved dopamine transmission. Eur J Nucl Med Mol Imaging. 2023 Nov 16. doi: 10.1007/s00259-023-06493-w. Epub ahead of print. PMID: 37971501.
2021
- Vöglein J, Kostova I, Arzberger T, Röber S, Schmitz P, Simons M, Ruf V, Windl O, Herms J, Dieterich M, Danek A, Höglinger GU, Giese A, Levin J (2021). First symptom guides diagnosis and prognosis in neurodegenerative diseases - a retrospective study of autopsy proven cases. Eur J Neurol. 2021 Mar 4. doi: 10.1111/ene.14800. Epub ahead of print. PMID: 33662165.
- Vöglein J, Kostova I, Arzberger T, Noachtar S, Dieterich M, Herms J, Schmitz P, Ruf V, Windl O, Roeber S, Simons M, Höglinger GU, Danek A, Giese A, Levin J (2021). Seizure prevalence in neurodegenerative diseases - a study of autopsy proven cases. Eur J Neurol. 2021 Sep 2. doi: 10.1111/ene.15089. Epub ahead of print. PMID: 34472165.PMC8161006.
- Xiang X, Wind K, Wiedemann T, Blume T, Shi Y, Briel N, Beyer L, Biechele G, Eckenweber F, Zatcepin A, Lammich S, Ribicic S, Tahirovic S, Willem M, Deussing M, Palleis C, Rauchmann BS, Gildehaus FJ, Lindner S, Spitz C, Franzmeier N, Baumann K, Rominger A, Bartenstein P, Ziegler S, Drzezga A, Respondek G, Buerger K, Perneczky R, Levin J, Höglinger GU, Herms J, Haass C, Brendel M (2021). Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases. Sci Transl Med. 2021 Oct 13;13(615):eabe5640. doi: 10.1126/scitranslmed.abe5640. Epub 2021 Oct 13. PMID: 34644146.
2020
- Jecmenica Lukic M, Kurz C, Respondek G, Grau-Rivera O, Compta Y, Gelpi E, Troakes C; Barcelona Brain Bank collaborative group, the MDS-endorsed PSP study group; van Swieten JC, Giese A, Roeber S, Arzberger T, Höglinger G. Copathology in Progressive Supranuclear Palsy: Does It Matter? Mov Disord. 2020 Jun;35(6):984-993. doi: 10.1002/mds.28011. Epub 2020 Mar 3. PMID: 32125724.
2018
- Bonham LW, Karch CM, Fan CC, Tan C, Geier EG, Wang Y, Wen N, Broce IJ, Li Y, Barkovich MJ, Ferrari R, Hardy J, Momeni P, Höglinger G, Müller U, Hess CP, Sugrue LP, Dillon WP, Schellenberg GD, Miller BL, Andreassen OA, Dale AM, Barkovich AJ, Yokoyama JS, Desikan RS; International FTD-Genomics Consortium (IFGC); International Parkinson’s Disease Genetics Consortium (IPDGC); International Genomics of Alzheimer’s Project (IGAP). CXCR4 involvement in neurodegenerative diseases. Transl Psychiatry. 2018 Apr 11;8(1):73. doi: 10.1038/s41398-017-0049-7. PMID: 29636460; PMCID: PMC5893558.
- Jabbari E, Woodside J, Tan MMX, Shoai M, Pittman A, Ferrari R, Mok KY, Zhang D, Reynolds RH, de Silva R, Grimm MJ, Respondek G, Müller U, Al-Sarraj S, Gentleman SM, Lees AJ, Warner TT, Hardy J, Revesz T, Höglinger GU, Holton JL, Ryten M, Morris HR. Variation at the TRIM11 locus modifies progressive supranuclear palsy phenotype. Ann Neurol. 2018 Oct;84(4):485-496. doi: 10.1002/ana.25308. Epub 2018 Sep 15. PMID: 30066433; PMCID: PMC6221133.
- Karch CM, Wen N, Fan CC, Yokoyama JS, Kouri N, Ross OA, Höglinger G, Müller U, Ferrari R, Hardy J, Schellenberg GD, Sleiman PM, Momeni P, Hess CP, Miller BL, Sharma M, Van Deerlin V, Smeland OB, Andreassen OA, Dale AM, Desikan RS; International Frontotemporal Dementia (FTD)–Genomics Consortium, International Collaboration for Frontotemporal Dementia, Progressive Supranuclear Palsy (PSP) Genetics Consortium, and International Parkinson’s Disease Genomics Consortium. Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum. JAMA Neurol. 2018 Jul 1;75(7):860-875. doi: 10.1001/jamaneurol.2018.0372. PMID: 29630712; PMCID: PMC6043387.