Hemmer, Bernhard

Bader JM, Makarov C, Richter S, Strauss MT, Held F, Wahle M, Lorenz MB, Pöschl L, Skowronek P, Thielert M, Berthele A, Zeng WF, Ammar C, Bludau I, Schubert B, Theis FJ, Gasperi C, Hemmer B, Mann M. Large-scale proteomics across neurological disorders uncovers biomarker panel and targets in multiple sclerosis. Cell. 2026 Feb 25:S0092-8674(26)00104-2. doi: 10.1016/j.cell.2026.01.017. Epub ahead of print. PMID: 41747728.
Corona A, Clarelli F, Pääkkönen K, Harroud A, Shchetynsky K, Zollo A, Mingione A, Sorosina M, Mascia E, Giordano A, Rocca MA, Piehl F, Stridh P, Hemmer B, Goris A, Dubois B, Søndergaard HB, Sellebjerg F, D'alfonso S, Harbo HF, Olsson T, Saarela J, Priori A, Filippi M, Kockum I, Esposito F, Martinelli Boneschi F. Pharmacogenomics of response to interferon-beta and glatiramer acetate in Multiple Sclerosis: A multi-centric study. Mult Scler. 2026 Mar 3:13524585261417130. doi: 10.1177/13524585261417130. Epub ahead of print. PMID: 41776383.
Hess F, Baki E, McGinnis J, Wiltgen T, Scholz H, Bernkopf K, Schneider G, Kirschke J, Sepp D, Hemmer B, Wunderlich S, Mühlau M. Temporal Patterns of Fever Onset as an Indicator of Etiology in Intracerebral Hemorrhage. Neurol Int. 2026 Apr 3;18(4):68. doi: 10.3390/neurolint18040068. PMID: 42042755; PMCID: PMC13119264.
Landt C, Held F, Kolotourou K, Guranda M, Vakrakou AG, Franz J, Thomas C, Schmiedeknecht MUH, Bergann K, Wrzos C, Endmayr V, Tsaktanis T, Zechel S, Ancău M, Misgeld T, Hakroush S, Hametner S, Rothhammer V, Höftberger R, Hemmer B, Stadelmann C, Nessler S. Complement C4d Informs the Differential Diagnosis of Inflammatory Demyelinating CNS Diseases. Neurol Neuroimmunol Neuroinflamm. 2026 Mar;13(2):e200528. doi: 10.1212/NXI.0000000000200528. Epub 2025 Dec 23. PMID: 41435221; PMCID: PMC12735299.
Menden B, Incebacak Eltemur RD, Demidov G, Sturm M, Park J, Huridou C, Fath F, Nümann A, Baumann A, Diets IJ, Dufke C, Regensburger M, Rönnefarth M, Wilke V, van Os N, Vielhaber S, Rattay TW, Kohl Z, Peralta S, Pereira Sena P, Kellner M, Weissert N, Traschütz A, Zeltner L, Boelmans K, Deininger N, Schütz L, Gross C, Hinojosa Amaya AB, Raupach K, Hengel H, Harmuth F, Admard J, Bader I, Baumann S, Bender F, Bevot A, Bischoff A, Boschann F, Buchert R, Buchzik D, Casadei N, Catarino CB, Cordts I, Cremer K, Doebler-Neumann M, Ehmke N, Elbracht M, Falb RJ, Feindt T, Fleszar Z, Gerstner L, Gläser D, Grasshoff U, Grosch S, Grundmann K, Gutschalk A, Haaga M, Hayer S, Hehr U, Hellenbroich Y, Henn W, Herr B, Herzog R, Horber V, Deppe J, Kaiser N, Kehrer C, Kehrer M, Kern J, Keßler C, Khuller K, Klinkhammer H, Kotzaeridou U, Krawitz P, Kreiss M, Küpper H, Kuster A, Laugwitz L, Lesemann A, Lichey N, Linden T, Macek B, Magg J, Mangold E, Manka E, Marquardt I, Mehnert K, Mengel D, Morlot S, Oehl-Jaschkowitz B, Pauly MG, Philipp M, Radelfahr F, Rautenberg M, Riess A, Saft C, Schlotter-Weigel B, Schmidt A, Schwaibold EMC, Spahlinger V, Spranger S, Steiner KM, Stendel C, Thieme A, Tzschach A, Velic A, Wiethoff S, Wilke C, Züchner S, Zittel S; Solve-RD consortium; Husain RA, Deschauer M, Distelmaier F, Dufke A, Graessner H, Hemmer B, Jacobi H, Klockgether T, Klopstock T, Kobeleva X, Korenke GC, Kuechler A, Kuhlenbäumer G, Kurth I, Nguyen HP, Wunderlich G, Zeuner KE, Klebe S, Auer-Grumbach M, Butryn M, Winkler J, Timmann D, Synofzik M, van de Warrenburg B, Schüle R, Schöls L, Ossowski S, Riess O, Weber JJ, Haack TB. Loss-of-function variants in the CAPN1 activator CD99L2 cause X-linked spastic ataxia. Nat Commun. 2026 Feb 14;17(1):1698. doi: 10.1038/s41467-026-69337-9. PMID: 41690933.
Oh J, Barkhof F, Bar-Or A, Ciccarrelli O, Coetzee T, Filippi M, Granziera C, Hacohen Y, Hemmer B, Kantarci OH, Kim HJ, Lebrun-Frenay C, Montalban X, Mowry E, Ontaneda D, Prat A, Reich DS, Rovira À, Sati P, Siva A, Solomon AJ, Sormani MP, Stankoff B, Thompson A, Tintore M, Traboulsee A, van der Walt A, Wiendl H, Calabresi PA. Challenges and future directions for multiple sclerosis after the 2024 McDonald diagnostic criteria. Nat Med. 2026 Jul 9. doi: 10.1038/s41591-026-04490-8. Epub ahead of print. PMID: 42426222.
Palleis C, Weidinger E, Maaß S, Linke M, Brendel M, Stöcklein S, Al Tawil A, Mansmann U, Teupser D, Borst T, Heimke-Brinck R, Hemmer B, Höglinger GU, Bidner H, Simons M, Levin J. Study protocol: double-blind, randomized, prospective, placebo controlled parallel group phase II study to investigate the effect of glycerol phenylbutyrate (GPB) on neurofilament light chain (NfL) levels in patients with corticobasal syndrome (CBS). Neurol Res Pract. 2026 Jul 3;8(1):54. doi: 10.1186/s42466-026-00504-5. PMID: 42400090; PMCID: PMC13332586.
Pretzsch R, El Mahdaoui S, Johnson P, Soares MD, Koerbel K, Held F, Bajrami A, Pozzilli V, Lucchini M, Barbuti E, Bartels F, Barket R, Cordano C, Hemmer B, Cagol A, Schiavetti I, Sormani MP; ECTRIMS Winter School 2024 study group. Neurofilament light chain as a surrogate candidate for disease activity in multiple sclerosis (LUMINOUS)-A meta-regression of randomized controlled trials. Mult Scler. 2026 Jan 23:13524585251407973. doi: 10.1177/13524585251407973. Epub ahead of print. PMID: 41574448.
Tahedl M, Wiltgen T, Voon CC, Lauerer M, Kirschke JS, Hemmer B, Mühlau M, Zimmer C, Wiestler B. Brain connectome reorganization across the lifespan in relapsing-remitting multiple sclerosis. Eur J Radiol. 2026 Apr 13;200:112867. doi: 10.1016/j.ejrad.2026.112867. Epub ahead of print. PMID: 41990686.

Afzali AM, Hemmer B. Response to Letter to the Editor: Clarifying Diagnostic Criteria and the Role of Serum Neurofilament Light Chain in Immune-Mediated Neuropathies. Eur J Neurol. 2025 Feb;32(2):e70072. doi: 10.1111/ene.70072. PMID: 39905705; PMCID: PMC11794235.
Baki E, Kehl V, Topka M, Hess F, Lambrecht S, Hemmer B, Wunderlich S, Haertl J. Increased middle cerebral artery velocity predicts malignant media infarction after endovascular stroke thrombectomy. Ther Adv Neurol Disord. 2025 Oct 2;18:17562864251374935. doi: 10.1177/17562864251374935. PMID: 41048572; PMCID: PMC12491812.c
Beyrle M, Sepp D, Eichinger P, Mühlau M, Berthele A, Engl C, Hemmer B, Zimmer C, Wiestler B, Kirschke JS, Kertels O. T1-weighted subtraction maps improve the detection of contrast-enhancing lesions in multiple sclerosis. Eur J Radiol. 2025 Nov 24;195:112576. doi: 10.1016/j.ejrad.2025.112576. Epub ahead of print. PMID: 41468656.
Buchka S, Hapfelmeier A, Kirschke JS, Steuerwald V, Naumann M, Soto-Rey I, Rohr SO, Kramer F, Behrens L, Oswald E, Kümpfel T, Zimmermann H, Hoffmann VS, Hagedorn M, Albashiti F, Krumbholz M, Ziemann U, Kohlbacher O, Sailer B, Braunmüller V, Biergans S, de Arruda Botelho Herr M, Ernemann U, Bürkle E, Bender B, Daul A, Ruff C, Römhild J, Wiestler B, Sepp D, Spengler H, Pallaoro P, Boeker M, Kohlmayer F, Dehmelt V, Berthele A, Mühlau M, Uibel P, Wauschkuhn J, Kuhn K, Senel M, Vardakas I, Taranu D, Kestler HA, Sollmann N, Irmak Ön B, Bilger S, Mansmann U, Bayas A, Havla J, Kowarik MC, Tumani H, Hemmer B; ProVal-MS Study Group. External validation of a multiple sclerosis treatment decision score using data from the ProVal-MS cohort study. Ther Adv Neurol Disord. 2025 Nov 21;18:17562864251391095. doi: 10.1177/17562864251391095. PMID: 41281704; PMCID: PMC12639221.
Darvishi S, Donnachie E, Uibel PA, Flaskamp M, Gasperi C, Hapfelmeier A, Hemmer B. Antibiotic drug use in the five years preceding the diagnosis of multiple sclerosis. Mult Scler Relat Disord. 2025 Feb 28;96:106366. doi: 10.1016/j.msard.2025.106366. Epub ahead of print. PMID: 40043555.
Dereli O, Behringer J, Berthele A, Hapfelmeier A, Hemmer B, Gasperi C. Insights Into Disability and Disability Progression in People With Multiple Sclerosis Using Large-Scale Healthcare Data. Eur J Neurol. 2025 Apr;32(4):e70124. doi: 10.1111/ene.70124. PMID: 40159595; PMCID: PMC11955418.
Hess F, McGinnis J, Baki E, Wiltgen T, Müller A, Maegerlein C, Kirschke J, Zimmer C, Hemmer B, Wunderlich S, Mühlau M. Predictors and Implications of Myocardial Injury in Intracerebral Hemorrhage. Clin Neuroradiol. 2025 Jan 30. doi: 10.1007/s00062-025-01498-4. Epub ahead of print. PMID: 39884976.
Lauerer M, Wiltgen T, Brückner C, Engl C, Giglhuber K, Lambrecht S, Pongratz V, Berthele A, Gasperi C, Kirschke JS, Zimmer C, Hemmer B, Mühlau M. Predictors of early disability accumulation in newly diagnosed multiple sclerosis: clinical, imaging and cerebrospinal fluid measures. J Neurol Neurosurg Psychiatry. 2025 Feb 17:jnnp-2024-335037. doi: 10.1136/jnnp-2024-335037. Epub ahead of print. PMID: 39961655.
Makarov C, Donnachie E, Hapfelmeier A, Hemmer B, Gasperi C. Early comorbidities and diagnostic challenges in people with multiple sclerosis with possible impact on disease management. Mult Scler J Exp Transl Clin. 2025 Feb 12;11(1):20552173251315458. doi: 10.1177/20552173251315458. PMID: 39944057; PMCID: PMC11815963.
Pukaj A, Harroud A, Shchetynsky K, Wirsching L, Peters L, Andlauer TFM, Pääkkönen K, Bos SD, Moylett S, Dubois B, Llufriu S, Luessi F, Tackenberg B, Kowarik MC, Then Bergh F, Trebst C, Tumani H, Wildemann B, Bayas A, Havla J, Kümpfel T, Knop M, Genetics Center R, Stridh P, Hillert JA, Olsson T, Alfredsson L, Cotsapas C, Flinstad Harbo H, Zipp F, Saarela J, Baranzini SE, Berthele A, Kockum I, Hemmer B, Gasperi C; MultipleMS consortium. Genetic Risk Variants for Multiple Sclerosis and Other Loci Linked to Intrathecal Immunoglobulin G Synthesis. Neurol Neuroimmunol Neuroinflamm. 2025 Nov;12(6):e200499. doi: 10.1212/NXI.0000000000200499. Epub 2025 Oct 15. PMID: 41092258; PMCID: PMC12533489.
Schraad M, Mäurer M, Salmen A, Ruck T, Uphaus T, Fleischer V, Luessi F, Protopapa M, Steffen F, Hanuscheck N, Pape K, Brummer T, Shin J, Korn T, Klotz L, Lünemann JD, Pawlitzki M, Weber MS, Bayas A, Wildemann B, Hartung HP, Then Bergh F, Warnke C, Zettl UK, Berthele A, Haghikia A, Linker R, Tumani H, Meuth SG, Hemmer B, Wiendl H, Kümpfel T, Gold R, Bittner S, Zipp F. Cellular and humoral vaccination response under immunotherapies-German consensus on vaccination strategies in neurological autoimmune diseases. Ther Adv Neurol Disord. 2025 Dec 12;18:17562864251396006. doi: 10.1177/17562864251396006. PMID: 41394285; PMCID: PMC12701252.
Voon CC, Meineke J, Wiltgen T, McGinnis J, Berg R, Preibisch C, Schlaeger S, Wiestler B, Engl C, Berthele A, Kirschke JS, Hemmer B, Mühlau M. Quantitative Susceptibility Mapping of Deep Grey Matter in MS: Association With Clinical Scores and Brain Volume Measures. Brain Behav. 2025 Oct;15(10):e70988. doi: 10.1002/brb3.70988. PMID: 41116625; PMCID: PMC12537832.

Afzali AM, Nirschl L, Sie C, Pfaller M, Ulianov O, Hassler T, Federle C, Petrozziello E, Kalluri SR, Chen HH, Tyystjärvi S, Muschaweckh A, Lammens K, Delbridge C, Büttner A, Steiger K, Seyhan G, Ottersen OP, Öllinger R, Rad R, Jarosch S, Straub A, Mühlbauer A, Grassmann S, Hemmer B, Böttcher JP, Wagner I, Kreutzfeldt M, Merkler D, Pardàs IB, Schmidt Supprian M, Buchholz VR, Heink S, Busch DH, Klein L, Korn T. B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature. 2024 Feb 21. doi: 10.1038/s41586-024-07079-8. Epub ahead of print. PMID: 38383779.
Afzali AM, Vosko M, Reinhardt N, Zinevych I, Gmeiner V, Korn T, Gasperi C, Berthele A, Feneberg E, Hemmer B. Serum neurofilament light chain predicts disease severity in axonal variants of acute immune neuropathies: A retrospective monocentric cohort study. Eur J Neurol. 2024 Nov 19:e16539. doi: 10.1111/ene.16539. Epub ahead of print. PMID: 39562307.
Amezcua L, Rotstein D, Shirani A, Ciccarelli O, Ontaneda D, Magyari M, Rivera V, Kimbrough D, Dobson R, Taylor B, Williams M, Marrie RA, Banwell B, Hemmer B, Newsome SD, Cohen JA, Solomon AJ, Royal W 3rd. Differential diagnosis of suspected multiple sclerosis: considerations in people from minority ethnic and racial backgrounds in North America, northern Europe, and Australasia. Lancet Neurol. 2024 Oct;23(10):1050-1062. doi: 10.1016/S1474-4422(24)00288-6. PMID: 39304244.
Ancău M, Tanti GK, Butenschoen VM, Gempt J, Yakushev I, Nekolla S, Mühlau M, Scheunemann C, Heininger S, Löwe B, Löwe E, Baer S, Fischer J, Reiser J, Ayachit SS, Liesche-Starnecker F, Schlegel J, Matiasek K, Schifferer M, Kirschke JS, Misgeld T, Lueth T, Hemmer B. Validating a minipig model of reversible cerebral demyelination using human diagnostic modalities and electron microscopy. EBioMedicine. 2024 Feb 1;100:104982. doi: 10.1016/j.ebiom.2024.104982. Epub ahead of print. PMID: 38306899.
Baki E, Baumgart L, Kehl V, Hess F, Wolff AW, Wagner A, Hernandez Petzsche MR, Boeckh-Behrens T, Hemmer B, Meyer B, Gempt J, Wunderlich S. Predictors of malignant swelling in space-occupying cerebellar infarction. Stroke Vasc Neurol. 2024 Aug 29:svn-2024-003360. doi: 10.1136/svn-2024-003360. Epub ahead of print. PMID: 39209704.
Baki E, Baumgart L, Kehl V, Hess F, Wolff AW, Wagner A, Hernandez Petzsche MR, Boeckh-Behrens T, Hemmer B, Meyer B, Gempt J, Wunderlich S. Functional Outcomes After Decompressive Surgery in Patients with Malignant Space-Occupying Cerebellar Infarction. Neurol Int. 2024 Oct 28;16(6):1239-1246. doi: 10.3390/neurolint16060094. PMID: 39585053; PMCID: PMC11587139.
Bayas A, Mansmann U, Ön BI, Hoffmann VS, Berthele A, Mühlau M, Kowarik MC, Krumbholz M, Senel M, Steuerwald V, Naumann M, Hartberger J, Kerschensteiner M, Oswald E, Ruschil C, Ziemann U, Tumani H, Vardakas I, Albashiti F, Kramer F, Soto-Rey I, Spengler H, Mayer G, Kestler HA, Kohlbacher O, Hagedorn M, Boeker M, Kuhn K, Buchka S, Kohlmayer F, Kirschke JS, Behrens L, Zimmermann H, Bender B, Sollmann N, Havla J, Hemmer B; ProVal-MS study group. Prospective study validating a multidimensional treatment decision score predicting the 24-month outcome in untreated patients with clinically isolated syndrome and early relapsing-remitting multiple sclerosis, the ProVal-MS study. Neurol Res Pract. 2024 Mar 7;6(1):15. doi: 10.1186/s42466-024-00310-x. PMID: 38449051; PMCID: PMC10918966.
Clarelli F, Corona A, Pääkkönen K, Sorosina M, Zollo A, Piehl F, Olsson T, Stridh P, Jagodic M, Hemmer B, Gasperi C, Harroud A, Shchetynsky K, Mingione A, Mascia E, Misra K, Giordano A, Mazzieri MLT, Priori A, Saarela J, Kockum I, Filippi M, Esposito F, Boneschi FGM. Pharmacogenomics of clinical response to Natalizumab in multiple sclerosis: a genome-wide multi-centric association study. J Neurol. 2024 Sep 12. doi: 10.1007/s00415-024-12608-6. Epub ahead of print. PMID: 39264442.

Chamberlain P, Hemmer B, Höfler J, Wessels H, von Richter O, Hornuss C, Poetzl J, Roth K. Comparative immunogenicity assessment of biosimilar natalizumab to its reference medicine: a matching immunogenicity profile. Front Immunol. 2024 Dec 19;15:1414304. doi: 10.3389/fimmu.2024.1414304. PMID: 39749348; PMCID: PMC11693714.
Correale J, Solomon AJ, Cohen JA, Banwell BL, Gracia F, Gyang TV, de Bedoya FHD, Harnegie MP, Hemmer B, Jacob A, Kim HJ, Marrie RA, Mateen FJ, Newsome SD, Pandit L, Prayoonwiwat N, Sahraian MA, Sato DK, Saylor D, Shi FD, Siva A, Tan K, Viswanathan S, Wattjes MP, Weinshenker B, Yamout B, Fujihara K. Differential diagnosis of suspected multiple sclerosis: global health considerations. Lancet Neurol. 2024 Oct;23(10):1035-1049. doi: 10.1016/S1474-4422(24)00256-4. PMID: 39304243.
Darvishi S, Donnachie E, Gasperi C, Hapfelmeier A, Hemmer B. Vaccination as a risk factor for pediatric multiple sclerosis: Insights from a retrospective case-control study. Mult Scler. 2024 Nov 14:13524585241297003. doi: 10.1177/13524585241297003. Epub ahead of print. PMID: 39540267.
Diddens J, Lepennetier G, Friedrich V, Schmidt M, Brand RM, Georgieva T, Hemmer B, Lehmann-Horn K. Single-Cell Profiling Indicates a Proinflammatory Role of Meningeal Ectopic Lymphoid Tissue in Experimental Autoimmune Encephalomyelitis. Neurol Neuroimmunol Neuroinflamm. 2024 Jan;11(1):e200185. doi: 10.1212/NXI.0000000000200185. Epub 2023 Dec 15. PMID: 38100739; PMCID: PMC10723639.
Greensmith R, Lape IT, Riella CV, Schubert AJ, Metzger JJ, Dighe AS, Tan X, Hemmer B, Rau J, Wendlinger S, Diederich N, Schütz A, Riella LV, Kaminski MM. CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment. EMBO Mol Med. 2024 Sep 13. doi: 10.1038/s44321-024-00126-x. Epub ahead of print. PMID: 39271961.
Gross CC, Schulte-Mecklenbeck A, Steinberg OV, Wirth T, Lauks S, Bittner S, Schindler P, Baranzini SE, Groppa S, Bellmann-Strobl J, Bünger N, Chien C, Dawin E, Eveslage M, Fleischer V, Gonzalez-Escamilla G, Gisevius B, Haas J, Kerschensteiner M, Kirstein L, Korsukewitz C, Lohmann L, Lünemann JD, Luessi F, Meyer Zu Hörste G, Motte J, Ruck T, Ruprecht K, Schwab N, Steffen F, Meuth SG, Paul F, Wildemann B, Kümpfel T, Gold R, Hahn T, Zipp F, Klotz L, Wiendl H; German Competence Network Multiple Sclerosis (KKNMS) [i.a. Hemmer B, Korn T]. Multiple sclerosis endophenotypes identified by high-dimensional blood signatures are associated with distinct disease trajectories. Sci Transl Med. 2024 Mar 27;16(740):eade8560. doi: 10.1126/scitranslmed.ade8560. Epub 2024 Mar 27. PMID: 38536936.
Held F, Makarov C, Gasperi C, Flaskamp M, Grummel V, Berthele A, Hemmer B. Proteomics Reveals Age as Major Modifier of Inflammatory CSF Signatures in Multiple Sclerosis. Neurol Neuroimmunol Neuroinflamm. 2025 Jan;12(1):e200322. doi: 10.1212/NXI.0000000000200322. Epub 2024 Nov 13. PMID: 39536291; PMCID: PMC11563564.
Hua LH, Solomon AJ, Tenembaum S, Scalfari A, Rovira À, Rostasy K, Newsome SD, Marrie RA, Magyari M, Kantarci O, Hemmer B, Hemingway C, Harnegie MP, Graves JS, Cohen JA, Bove R, Banwell B, Corboy JR, Waubant E. Differential Diagnosis of Suspected Multiple Sclerosis in Pediatric and Late-Onset Populations: A Review. JAMA Neurol. 2024 Sep 16. doi: 10.1001/jamaneurol.2024.3062. Epub ahead of print. PMID: 39283621.

Jacobs BM, Gasperi C, Kalluri SR, Al-Najjar R, McKeon MO, Else J, Pukaj A, Held F, Sawcer S, Ban M, Hemmer B. Single-cell analysis of cerebrospinal fluid reveals common features of neuroinflammation. Cell Rep Med. 2024 Dec 13:101733. doi: 10.1016/j.xcrm.2024.101733. Epub ahead of print. PMID: 39708811.
Linnerbauer M, Lößlein L, Vandrey O, Peter A, Han Y, Tsaktanis T, Wogram E, Needhamsen M, Kular L, Nagel L, Zissler J, Andert M, Meszaros L, Hanspach J, Zuber F, Naumann UJ, Diebold M, Wheeler MA, Beyer T, Nirschl L, Cirac A, Laun FB, Günther C, Winkler J, Bäuerle T, Jagodic M, Hemmer B, Prinz M, Quintana FJ, Rothhammer V. The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology. Nat Immunol. 2024 Mar;25(3):432-447. doi: 10.1038/s41590-024-01756-6. Epub 2024 Feb 26. PMID: 38409259; PMCID: PMC10907300.
Mandler JM, Härtl J, Cordts I, Sturm M, Hedderich DM, Bafligil C, Baki E, Becker B, Machetanz G, Haack TB, Berthele A, Hemmer B, Deschauer M. Uncovering genetic mimics in multiple sclerosis: A single-center clinical exome sequencing study. Mult Scler J Exp Transl Clin. 2024 Jul 24;10(3):20552173241263491. doi: 10.1177/20552173241263491. PMID: 39072298; PMCID: PMC11273569.
Quint P, Schroeter CB, Kohle F, Öztürk M, Meisel A, Tamburrino G, Mausberg AK, Szepanowski F, Afzali AM, Fischer K, Nelke C, Räuber S, Voth J, Masanneck L, Willison A, Vogelsang A, Hemmer B, Berthele A, Schroeter M, Hartung HP, Pawlitzki M, Schreiber S, Stettner M, Maus U, Meuth SG, Stascheit F, Ruck T. Preventing long-term disability in CIDP: the role of timely diagnosis and treatment monitoring in a multicenter CIDP cohort. J Neurol. 2024 Jul 11. doi: 10.1007/s00415-024-12548-1. Epub ahead of print. PMID: 38990346.
Wicklein R, Kreitner L, Wild A, Aly L, Rueckert D, Hemmer B, Korn T, Menten MJ, Knier B. Retinal small vessel pathology is associated with disease burden in multiple sclerosis. Mult Scler. 2024 May 15:13524585241247775. doi: 10.1177/13524585241247775. Epub ahead of print. PMID: 38751230.
Wiltgen T, McGinnis J, Schlaeger S, Kofler F, Voon C, Berthele A, Bischl D, Grundl L, Will N, Metz M, Schinz D, Sepp D, Prucker P, Schmitz-Koep B, Zimmer C, Menze B, Rueckert D, Hemmer B, Kirschke J, Mühlau M, Wiestler B. LST-AI: A deep learning ensemble for accurate MS lesion segmentation. Neuroimage Clin. 2024 Apr 29;42:103611. doi: 10.1016/j.nicl.2024.103611. Epub ahead of print. PMID: 38703470; PMCID: PMC11088188.
Wolf E, Wicklein R, Aly L, Schmaderer C, Afzali AM, Mardin C, Korn T, Hemmer B, Hofauer B, Knier B. Optical coherence tomography angiography suggests different retinal pathologies in multiple sclerosis and Sjögren's syndrome. J Neurol. 2024 May 14. doi: 10.1007/s00415-024-12414-0. Epub ahead of print. PMID: 38743089.

Afzali AM, Moog P, Kalluri SR, Hofauer B, Knopf A, Kirschke JS, Hemmer B, Berthele A (2023). CNS demyelinating events in primary Sjögren's syndrome: A single-center case series on the clinical phenotype. Front Neurol. 2023 Feb 16;14:1128315. doi: 10.3389/fneur.2023.1128315. PMID: 36873454; PMCID: PMC9978709.
Bauswein M, Knoll G, Schmidt B, Gessner A, Hemmer B, Flaskamp M (2023). No evidence of an association of multiple sclerosis (MS) with Borna disease virus 1 (BoDV-1) infections in patients within an endemic region: a retrospective pilot study. Infection. 2023 Oct 9. doi: 10.1007/s15010-023-02099-4. Epub ahead of print. PMID: 37814203.
Bernhardt AM, Tiedt S, Teupser D, Dichgans M, Meyer B, Gempt J, Kuhn PH, Simons M, Palleis C, Weidinger E, Nübling G, Holdt L, Hönikl L, Gasperi C, Giesbertz P, Müller SA, Breimann S, Lichtenthaler SF, Kuster B, Mann M, Imhof A, Barth T, Hauck SM, Zetterberg H, Otto M, Weichert W, Hemmer B, Levin J (2023). A unified classification approach rating clinical utility of protein biomarkers across neurologic diseases. EBioMedicine. 2023 Feb 4;89:104456. doi: 10.1016/j.ebiom.2023.104456. Epub ahead of print. PMID: 36745974; PMCID: PMC9931915.
Darvishi S, Donnachie E, Gasperi C, Hapfelmeier A, Hemmer B (2023). Vaccination frequency in people newly diagnosed with multiple sclerosis. Mult Scler. 2023 Oct 13:13524585231199084. doi: 10.1177/13524585231199084. Epub ahead of print. PMID: 37830337.
Gasperi C, Wiltgen T, McGinnis J, Cerri S, Moridi T, Ouellette R, Pukaj A, Voon C, Bafligil C, Lauerer M, Andlauer TFM, Held F, Aly L, Shchetynsky K, Stridh P, Harroud A, Wiestler B, Kirschke JS, Zimmer C, Baras A, Piehl F, Berthele A, Granberg T, Kockum I, Hemmer B, Mühlau M (2023). A genetic risk variant for multiple sclerosis severity is associated with brain atrophy. Ann Neurol. 2023 Sep 27. doi: 10.1002/ana.26807. Epub ahead of print. PMID: 37753809.
Haertl J, Renz M, Wunderlich S, Hemmer B, Hofauer B, Gempt J, Kallmayer M, Boeckh-Behrens T, Kirschke JS, Ikenberg BD (2023). Bony Stroke: Ischemic Stroke Caused by Mechanical Stress on Brain Supplying Arteries From Anatomical Bone or Cartilage Anomalies. Stroke. 2023 Apr 13. doi: 10.1161/STROKEAHA.122.041946. Epub ahead of print. PMID: 37051911.
Hapfelmeier A, On BI, Mühlau M, Kirschke JS, Berthele A, Gasperi C, Mansmann U, Wuschek A, Bussas M, Boeker M, Bayas A, Senel M, Havla J, Kowarik MC, Kuhn K, Gatz I, Spengler H, Wiestler B, Grundl L, Sepp D, Hemmer B. (2023). Retrospective cohort study to devise a treatment decision score predicting adverse 24-month radiological activity in early multiple sclerosis. Ther Adv Neurol Disord. 2023 Mar 24;16:17562864231161892. doi: 10.1177/17562864231161892. PMID: 36993939; PMCID: PMC10041597.
Hemmer B, Wiendl H, Roth K, Wessels H, Höfler J, Hornuss C, Liedert B, Selmaj K (2023). Efficacy and Safety of Proposed Biosimilar Natalizumab (PB006) in Patients With Relapsing-Remitting Multiple Sclerosis: The Antelope Phase 3 Randomized Clinical Trial. JAMA Neurol. 2023 Jan 23. doi: 10.1001/jamaneurol.2022.5007. Epub ahead of print. PMID: 36689214.
International Multiple Sclerosis Genetics Consortium; MultipleMS Consortiumm [Hemmer B] (2023). Locus for severity implicates CNS resilience in progression of multiple sclerosis. Nature. 2023 Jun 28. doi: 10.1038/s41586-023-06250-x. Epub ahead of print. PMID: 37380766.
Kapell H, Fazio L, Dyckow J, Schwarz S, Cruz-Herranz A, Mayer C, Campos J, D Este E, Möbius W, Cordano C, Pröbstel AK, Gharagozloo M, Zulji A, Narayanan Naik V, Delank AK, Cerina M, Müntefering T, Lerma-Martin C, Sonner JK, Sin JH, Disse P, Rychlik N, Sabeur K, Chavali M, Srivastava R, Heidenreich M, Fitzgerald KC, Seebohm G, Stadelmann C, Hemmer B, Platten M, Jentsch TJ, Engelhardt M, Budde T, Nave KA, Calabresi PA, Friese MA, Green AJ, Acuna C, Rowitch DH, Meuth SG, Schirmer L (2023). Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination. J Clin Invest. 2023 Jan 31:e164223. doi: 10.1172/JCI164223. Epub ahead of print. PMID: 36719741.
Klein A, Flaskamp M, Berthele A, Held F, Muratovic H, Hemmer B (2023). The impact of disease-modifying therapies on immunoglobulin blood levels in patients with multiple sclerosis: a retrospective cross-sectional study. Ther Adv Neurol Disord. 2023 Apr 17;16:17562864231162661. doi: 10.1177/17562864231162661. PMID: 37114068; PMCID: PMC10126592.
Lauerer M, McGinnis J, Bussas M, El Husseini M, Pongratz V, Engl C, Wuschek A, Berthele A, Riederer I, Kirschke JS, Zimmer C, Hemmer B, Mühlau M (2023). Prognostic value of spinal cord lesion measures in early relapsing-remitting multiple sclerosis. J Neurol Neurosurg Psychiatry. 2023 Jul 26:jnnp-2023-331799. doi: 10.1136/jnnp-2023-331799. Epub ahead of print. PMID: 37495267.
Linnerbauer M, Beyer T, Nirschl L, Farrenkopf D, Lößlein L, Vandrey O, Peter A, Tsaktanis T, Kebir H, Laplaud D, Oellinger R, Engleitner T, Alvarez JI, Rad R, Korn T, Hemmer B, Quintana FJ, Rothhammer V (2023). PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation. Nat Commun. 2023 Sep 9;14(1):5555. doi: 10.1038/s41467-023-40982-8. PMID: 37689786; PMCID: PMC10492803.
Otero-Romero S, Lebrun-Frénay C, Reyes S, Amato MP, Campins M, Farez M, Filippi M, Hacohen Y, Hemmer B, Juuti R, Magyari M, Oreja-Guevara C, Siva A, Vukusic S, Tintoré M (2023). ECTRIMS/EAN consensus on vaccination in people with multiple sclerosis: Improving immunization strategies in the era of highly active immunotherapeutic drugs. Mult Scler. 2023 Jun 9:13524585231168043. doi: 10.1177/13524585231168043. Epub ahead of print. PMID: 37293841.
Otero-Romero S, Lebrun-Frénay C, Reyes S, Amato MP, Campins M, Farez M, Filippi M, Hacohen Y, Hemmer B, Juuti R, Magyari M, Oreja-Guevara C, Siva A, Vukusic S, Tintoré M (2023). European Committee for Treatment and Research in Multiple Sclerosis and European Academy of Neurology consensus on vaccination in people with multiple sclerosis: Improving immunization strategies in the era of highly active immunotherapeutic drugs. Eur J Neurol. 2023 Jun 9. doi: 10.1111/ene.15809. Epub ahead of print. PMID: 37293849.
Pongratz V, Bussas M, Schmidt P, Grahl S, Gasperi C, El Husseini M, Harabacz L, Pineker V, Sepp D, Grundl L, Wiestler B, Kirschke J, Zimmer C, Berthele A, Hemmer B, Mühlau M (2023). Lesion location across diagnostic regions in multiple sclerosis. Neuroimage Clin. 2023 Jan 5;37:103311. doi: 10.1016/j.nicl.2022.103311. Epub ahead of print. PMID: 36623350; PMCID: PMC9850035.
Romahn EF, Wiltgen T, Bussas M, Aly L, Wicklein R, Noll C, Berthele A, Dehmelt V, Mardin C, Zimmer C, Korn T, Hemmer B, Kirschke JS, Mühlau M, Knier B. Association of retinal vessel pathology and brain atrophy in relapsing-remitting multiple sclerosis. Front Immunol. 2023 Nov 28;14:1284986. doi: 10.3389/fimmu.2023.1284986. PMID: 38090586; PMCID: PMC10715309.
Salmen A, Hoepner R, Fleischer V, Heldt M, Gisevius B, Motte J, Ruprecht K, Schneider R, Fisse AL, Grüter T, Lukas C, Berthele A, Giglhuber K, Flaskamp M, Mühlau M, Kirschke J, Bittner S, Groppa S, Lüssi F, Bayas A, Meuth S, Heesen C, Trebst C, Wildemann B, Then Bergh F, Antony G, Kümpfel T, Paul F, Nischwitz S, Tumani H, Zettl U, Hemmer B, Wiendl H, Zipp F, Gold R (2023). Factors associated with depressive mood at the onset of multiple sclerosis - an analysis of 781 patients of the German NationMS cohort. Ther Adv Neurol Disord. 2023 Sep 8;16:17562864231197309. doi: 10.1177/17562864231197309. PMID: 37692259; PMCID: PMC10492471.
Solomon AJ, Arrambide G, Brownlee WJ, Flanagan EP, Amato MP, Amezcua L, Banwell BL, Barkhof F, Corboy JR, Correale J, Fujihara K, Graves J, Harnegie MP, Hemmer B, Lechner-Scott J, Marrie RA, Newsome SD, Rocca MA, Royal W 3rd, Waubant EL, Yamout B, Cohen JA (2023). Differential diagnosis of suspected multiple sclerosis: an updated consensus approach. Lancet Neurol. 2023 Aug;22(8):750-768. doi: 10.1016/S1474-4422(23)00148-5. PMID: 37479377.
Tahedl M, Wiltgen T, Voon CC, Berthele A, Kirschke JS, Hemmer B, Mühlau M, Zimmer C, Wiestler B (2023). Benefits of a mosaic approach for assessing cortical atrophy in individual multiple sclerosis patients. Brain Behav. 2023 Nov 13:e3327. doi: 10.1002/brb3.3327. Epub ahead of print. PMID: 37961043.
Tahedl M, Wiltgen T, Voon CC, Berthele A, Kirschke JS, Hemmer B, Mühlau M, Zimmer C, Wiestler B. Cortical Thin Patch Fraction Reflects Disease Burden in MS: The Mosaic Approach. AJNR Am J Neuroradiol. 2023 Dec 21;45(1):82–9. doi: 10.3174/ajnr.A8064. Epub ahead of print. PMID: 38164526; PMCID: PMC10756581.
Tsaktanis T, Linnerbauer M, Lößlein L, Farrenkopf D, Vandrey O, Peter A, Cirac A, Beyer T, Nirschl L, Grummel V, Mühlau M, Bussas M, Hemmer B, Quintana FJ, Rothhammer V (2023). Regulation of the programmed cell death protein 1/programmed cell death ligand 1 axis in relapsing-remitting multiple sclerosis. Brain Commun. 2023 Jul 25;5(4):fcad206. doi: 10.1093/braincomms/fcad206. PMID: 37564830; PMCID: PMC10411318.
Wauschkuhn J, Solorza Buenrostro G, Aly L, Asseyer S, Wicklein R, Hartberger JM, Ruprecht K, Mühlau M, Schmitz-Hübsch T, Chien C, Berthele A, Brandt AU, Korn T, Paul F, Hemmer B, Zimmermann HG, Knier B (2023). Retinal ganglion cell loss is associated with future disability worsening in early relapsing-remitting multiple sclerosis. Eur J Neurol. 2023 Jan 12. doi: 10.1111/ene.15681. Epub ahead of print. PMID: 36635219.
Wicklein R, Yam C, Noll C, Aly L, Banze N, Romahn EF, Wolf E, Hemmer B, Oertel FC, Zimmermann H, Albrecht P, Ringelstein M, Baumann C, Feucht N, Penkava J, Havla J, Gernert JA, Mardin C, Vasileiou ES, Van Der Walt A, Al-Louzi O, Cabello S, Vidal-Jordana A, Krämer J, Wiendl H, Preiningerova JL, Ciccarelli O, Garcia-Martin E, Kana V, Calabresi PA, Paul F, Saidha S, Petzold A, Toosy AT, Knier B; IMSVISUAL Consortium (2023). The OSCAR-MP Consensus Criteria for Quality Assessment of Retinal Optical Coherence Tomography Angiography. Neurol Neuroimmunol Neuroinflamm. 2023 Oct 9;10(6):e200169. doi: 10.1212/NXI.0000000000200169. PMID: 37813596; PMCID: PMC10574825.

Aly L, Noll C, Wicklein R, Wolf E, Romahn EF, Wauschkuhn J, Hosari S, Mardin C, Berthele A, Hemmer B, Korn T, Knier B (2022). Dynamics of Retinal Vessel Loss After Acute Optic Neuritis in Patients With Relapsing Multiple Sclerosis. Neurol Neuroimmunol Neuroinflamm. 2022 Mar 17;9(3):e1159. doi: 10.1212/NXI.0000000000001159. PMID: 35301260; PMCID: PMC8931743.
Ancau M, Liesche-Starnecker F, Niederschweiberer J, Krieg SM, Zimmer C, Lingg C, Kumpfmüller D, Ikenberg B, Ploner M, Hemmer B, Wunderlich S, Mühlau M, Knier B (2022). Case Series: Acute Hemorrhagic Encephalomyelitis After SARS-CoV-2 Vaccination. Front Neurol. 2022 Feb 2;12:820049. doi: 10.3389/fneur.2021.820049. PMID: 35185757; PMCID: PMC8847228.
Bussas M, El Husseini M, Harabacz L, Pineker V, Grahl S, Pongratz V, Berthele A, Riederer I, Zimmer C, Hemmer B, Kirschke JS, Mühlau M (2022). Multiple sclerosis lesions and atrophy in the spinal cord: Distribution across vertebral levels and correlation with disability. Neuroimage Clin. 2022;34:103006. doi: 10.1016/j.nicl.2022.103006. Epub 2022 Apr 13. PMID: 35468568; PMCID: PMC9059154.
Coronel-Castello SP, Lepennetier G, Diddens J, Friedrich V, Pfaller M, Hemmer B, Lehmann-Horn K (2022). Intrathecally Expanding B Cell Clones in Herpes Simplex Encephalitis: A Case Report. Neurol Ther. 2022 Feb 6. doi: 10.1007/s40120-022-00330-2. Epub ahead of print. PMID: 35124795.
Del Poeta M, Ward BJ, Greenberg B, Hemmer B, Cree BAC, Komatireddy S, Mishra J, Sullivan R, Kilaru A, Moore A, Hach T, Berger JR (2022). Cryptococcal Meningitis Reported With Fingolimod Treatment: Case Series. Neurol Neuroimmunol Neuroinflamm. 2022 Mar 22;9(3):e1156. doi: 10.1212/NXI.0000000000001156. PMID: 35318259; PMCID: PMC8941596.
Gasperi C, Hapfelmeier A, Schneider A, Kuhn KA, Donnachie E, Hemmer B (2022). Association of pregnancies with risk of multiple sclerosis. Mult Scler. 2022 Mar 18:13524585221080542. doi: 10.1177/13524585221080542. Epub ahead of print. PMID: 35301890.
Gernert JA, Wicklein R, Hemmer B, Kümpfel T, Knier B, Havla J (2022). Peripapillary hyper-reflective ovoid mass-like structures (PHOMS) in AQP4-IgG-positive neuromyelitis optica spectrum disease (NMOSD) and MOG-IgG-associated disease (MOGAD). J Neurol. 2022 Oct 16. doi: 10.1007/s00415-022-11381-8. Epub ahead of print. PMID: 36245037.
Härtl J, Hartberger J, Wunderlich S, Cordts I, Bafligil C, Sturm M; Regeneron Genetics Center, Westphal D, Haack T, Hemmer B, Ikenberg BD, Deschauer M (2022). Exome-based gene panel analysis in a cohort of acute juvenile ischemic stroke patients:relevance of NOTCH3 and GLA variants. J Neurol. 2022 Nov 21. doi: 10.1007/s00415-022-11401-7. Epub ahead of print. PMID: 36411388.
Herwerth M, Kenet S, Schifferer M, Winkler A, Weber M, Snaidero N, Wang M, Lohrberg M, Bennett JL, Stadelmann C, Hemmer B, Misgeld T (2022). A new form of axonal pathology in a spinal model of neuromyelitis optica. Brain. 2022 Feb 24:awac079. doi: 10.1093/brain/awac079. Epub ahead of print. PMID: 35202467.
121. Kalluri SR, Srivastava R, Kenet S, Tanti GK, Dornmair K, Bennett JL, Misgeld T, Hemmer B, Wyss MT, Herwerth M (2022). P2R Inhibitors Prevent Antibody-Mediated Complement Activation in an Animal Model of Neuromyelitis Optica : P2R Inhibitors Prevent Autoantibody Injury. Neurotherapeutics. 2022 Jul 12. doi: 10.1007/s13311-022-01269-w. Epub ahead of print. PMID: 35821382.
Kenney RC, Liu M, Hasanaj L, Joseph B, Al-Hassan AA, Balk LJ, Behbehani R, Brandt A, Calabresi PA, Frohman E, Frohman TC, Havla J, Hemmer B, Jiang H, Knier B, Korn T, Leocani L, Martinez-Lapiscina EH, Papadopoulou A, Paul F, Petzold A, Pisa M, Villoslada P, Zimmermann H, Thorpe LE, Ishikawa H, Schuman JS, Wollstein G, Chen Y, Saidha S, Galetta S, Balcer LJ (2022). The Role of OCT Criteria and Machine Learning in Multiple Sclerosis and Optic Neuritis Diagnosis. Neurology. 2022 Jun 28:10.1212/WNL.0000000000200883. doi: 10.1212/WNL.0000000000200883. Epub ahead of print. PMID: 35764402.
Kenney R, Liu M, Hasanaj L, Joseph B, Al-Hassan AA, Balk L, Behbehani R, Brandt AU, Calabresi PA, Frohman EM, Frohman T, Havla J, Hemmer B, Jiang H, Knier B, Korn T, Leocani L, Martínez-Lapiscina EH, Papadopoulou A, Paul F, Petzold A, Pisa M, Villoslada P, Zimmermann H, Ishikawa H, Schuman JS, Wollstein G, Chen Y, Saidha S, Thorpe LE, Galetta SL, Balcer LJ, IMSVISUAL Consortium. (2022). Normative Data and Conversion Equation for Spectral-Domain Optical Coherence Tomography in an International Healthy Control Cohort. J Neuroophthalmol. 2022 Oct 18. doi: 10.1097/WNO.0000000000001717. Epub ahead of print. PMID: 36049213.
Kokas Z, Járdánházy A, Sandi D, Biernacki T, Fricska-Nagy Z, Füvesi J, Bartosik-Psujek H, Kes VB, Berger T, Berthele A, Drulovic J, Hemmer B, Horakova D, Ledinek AH, Havrdova EK, Magyari M, Rejdak K, Tiu C, Turcani P, Klivényi P, Kincses ZT, Vécsei L, Bencsik K (2022). Real-world operation of multiple sclerosis centres in Central-Eastern European countries covering 107 million inhabitants. Mult Scler Relat Disord. 2022 Nov 8;69:104406. doi: 10.1016/j.msard.2022.104406. Epub ahead of print. PMID: 36413917.
Lauerer M, Bussas M, Pongratz V, Berthele A, Kirschke JS, Wiestler B, Zimmer C, Hemmer B, Mühlau M (2022). Percentage brain volume change in multiple sclerosis mainly reflects white matter and cortical volume. Ann Clin Transl Neurol. 2022 Nov 25. doi: 10.1002/acn3.51700. Epub ahead of print. PMID: 36427289.
Lutfullin I, Eveslage M, Bittner S, Antony G, Flaskamp M, Luessi F, Salmen A, Gisevius B, Klotz L, Korsukewitz C, Berthele A, Groppa S, Then Bergh F, Wildemann B, Bayas A, Tumani H, Meuth SG, Trebst C, Zettl UK, Paul F, Heesen C, Kuempfel T, Gold R, Hemmer B, Zipp F, Wiendl H, Lünemann JD; German Competence Network Multiple Sclerosis (KKNMS) (2022). Association of obesity with disease outcome in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2022 Nov 1:jnnp-2022-329685. doi: 10.1136/jnnp-2022-329685. Epub ahead of print. PMID: 36319190.
Marrie RA, Allegretta M, Barcellos LF, Bebo B, Calabresi PA, Correale J, Davis B, De Jager PL, Gasperi C, Greenbaum C, Helme A, Hemmer B, Kanellis P, Kostich W, Landsman D, Lebrun-Frenay C, Makhani N, Munger KL, Okuda DT, Ontaneda D, Postuma RB, Quandt JA, Roman S, Saidha S, Sormani MP, Strum J, Valentine P, Walton C, Zackowski KM, Zhao Y, Tremlett H (2022). From the prodromal stage of multiple sclerosis to disease prevention. Nat Rev Neurol. 2022 Jul 15. doi: 10.1038/s41582-022-00686-x. Epub ahead of print. PMID: 35840705.
Niederschweiberer J, Schumacher NU, Kumpfmüller D, Lingg C, Graf S, Ikenberg B, Mühlau M, Lingor P, Hemmer B, Knier (2022). Das Anti-IgLON5-Syndrom in der klinischen Neurologie – zwei Fallberichte. Nervenarzt. 2022 Jun 15. German. doi: 10.1007/s00115-022-01344-9. Epub ahead of print. PMID: 35704066.
Noll C, Hiltensperger M, Aly L, Wicklein R, Afzali AM, Mardin C, Gasperi C, Berthele A, Hemmer B, Korn T, Knier B (2022). Association of the retinal vasculature, intrathecal immunity, and disability in multiple sclerosis. Front Immunol. 2022 Nov 11;13:997043. doi: 10.3389/fimmu.2022.997043. PMID: 36439131; PMCID: PMC9695398.
Schneider A, Fasshauer E, Scheiderbauer J, Warnke C, Köpke S, Kasper J, Toussaint M, Temmes H, Hemmer B, Schiffmann I, Rahn AC, Heesen C (2022). Development and evaluation of evidence-based patient information handbooks about multiple sclerosis immunotherapies. Mult Scler Relat Disord. 2022 Mar 10;60:103728. doi: 10.1016/j.msard.2022.103728. Epub ahead of print. PMID: 35290898.
Tur C, Dubessy AL, Otero-Romero S, Amato MP, Derfuss T, Di Pauli F, Iacobaeus E, Mycko M, Abboud H, Achiron A, Bellinvia A, Boyko A, Casanova JL, Clifford D, Dobson R, Farez MF, Filippi M, Fitzgerald KC, Fonderico M, Gouider R, Hacohen Y, Hellwig K, Hemmer B, Kappos L, Ladeira F, Lebrun-Frénay C, Louapre C, Magyari M, Mehling M, Oreja-Guevara C, Pandit L, Papeix C, Piehl F, Portaccio E, Ruiz-Camps I, Selmaj K, Simpson-Yap S, Siva A, Sorensen PS, Sormani MP, Trojano M, Vaknin-Dembinsky A, Vukusic S, Weinshenker B, Wiendl H, Winkelmann A, Zuluaga Rodas MI, Tintoré M, Stankoff B (2022). The risk of infections for multiple sclerosis and neuromyelitis optica spectrum disorder disease-modifying treatments: Eighth European Committee for Treatment and Research in Multiple Sclerosis Focused Workshop Review. April 2021. Mult Scler. 2022 Feb 23:13524585211069068. doi: 10.1177/13524585211069068. Epub ahead of print. PMID: 35196927.
Wenzel M, Afzali AM, Hoffmann D, Zange S, Georgi E, Hemmer B (2022). Toscana Virus Meningoencephalitis in Upper Bavaria. Dtsch Arztebl Int. 2022 Aug 8;119(31-32):546-547. doi: 10.3238/arztebl.m2022.0224. PMID: 36384926; PMCID: PMC9677540.
Wuschek A, Bussas M, El Husseini M, Harabacz L, Pineker V, Pongratz V, Berthele A, Riederer I, Zimmer C, Hemmer B, Kirschke JS, Mühlau M (2022). Somatosensory evoked potentials and magnetic resonance imaging of the central nervous system in early multiple sclerosis. J Neurol. 2022 Oct 7. doi: 10.1007/s00415-022-11407-1. Epub ahead of print. PMID: 36205793.

Aly L, Strauß EM, Feucht N, Weiß I, Berthele A, Mitsdoerffer M, Haass C, Hemmer B, Maier M, Korn T, Knier B (2021). Optical coherence tomography angiography indicates subclinical retinal disease in neuromyelitis optica spectrum disorders. Mult Scler. 2021 Jul 14:13524585211028831. doi: 10.1177/13524585211028831. Epub ahead of print. PMID: 34259579.
Boeckh-Behrens T, Golkowski D, Ikenberg B, Schlegel J, Protzer U, Schulz C, Novotny J, Kreiser K, Zimmer C, Hemmer B, Wunderlich S (2021). COVID-19-associated Large Vessel Stroke in a 28-year-old Patient : NETs and Platelets Possible Key Players in Acute Thrombus Formation. Clin Neuroradiol. 2021 Jan 29:1–4. doi: 10.1007/s00062-020-00992-1. Epub ahead of print. PMID: 33512534; PMCID: PMC7844783.
Brand RM, Friedrich V, Diddens J, Pfaller M, Romana de Franchis F, Radbruch H, Hemmer B, Steiger K, Lehmann-Horn K (2021). Anti-CD20 Depletes Meningeal B Cells but Does Not Halt the Formation of Meningeal Ectopic Lymphoid Tissue. Neurol Neuroimmunol Neuroinflamm. 2021 May 21;8(4):e1012. doi: 10.1212/NXI.0000000000001012. PMID: 34021057; PMCID: PMC8143698.
Brand RM, Diddens J, Friedrich V, Pfaller M, Radbruch H Hemmer B, Steiger K, Lehmann-Horn K (2021). Siponimod Inhibits the Formation of Meningeal Ectopic Lymphoid Tissue in Experimental Autoimmune Encephalomyelitis. Neurol Neuroimmunol Neuroinflamm. 2021 Dec 15;9(1):e1117. doi: 10.1212/NXI.0000000000001117. PMID: 34911793; PMCID: PMC8674936.PMC8172942.
Bussas M, Grahl S, Pongratz V, Berthele A, Gasperi C, Andlauer T, Gaser C, Kirschke JS, Wiestler B, Zimmer C, Hemmer B, Mühlau M (2021). Gray matter atrophy in relapsing-remitting multiple sclerosis is associated with white matter lesions in connecting fibers. Mult Scler. 2021 Sep 30:13524585211044957. doi: 10.1177/13524585211044957. Epub ahead of print. PMID: 34591698.
Cirac A, Tsaktanis T, Beyer T, Linnerbauer M, Andlauer T, Grummel V, Nirschl L, Loesslein L, Quintana FJ, Hemmer B, Rothhammer V (2021). The Aryl Hydrocarbon Receptor-Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis. Neurol Neuroimmunol Neuroinflamm. 2021 Jul 23;8(5):e1043. doi: 10.1212/NXI.0000000000001043. PMID: 34301821; PMCID: PMC8312279.
Cordts I, Hecker JS, Gauck D, Park J, Härtl J, Günthner R, Hammitzsch A, Schoser B, Abeck D, Götze KS, Haack TB, Deschauer M, Moog P, Hemmer B (2021). Successful treatment with azacitidine in VEXAS syndrome with prominent myofasciitis. Rheumatology (Oxford). 2021 Dec 11:keab866. doi: 10.1093/rheumatology/keab866. Epub ahead of print. PMID: 34894213.
Gasperi C, Hapfelmeier A, Daltrozzo T, Schneider A, Donnachie E, Hemmer B (2021). Systematic Assessment of Medical Diagnoses Preceding the First Diagnosis of Multiple Sclerosis. Neurology. 2021 Apr 26:10.1212/WNL.0000000000012074. doi: 10.1212/WNL.0000000000012074. Epub ahead of print. PMID: 33903190.
Grahl S, Bussas M, Wiestler B, Eichinger P, Gaser C, Kirschke J, Zimmer C, Berthele A, Hemmer B, Mühlau M (2021). Differential Effects of Fingolimod and Natalizumab on Magnetic Resonance Imaging Measures in Relapsing-Remitting Multiple Sclerosis. Neurotherapeutics. 2021 Sep 24. doi: 10.1007/s13311-021-01118-2. Epub ahead of print. PMID: 34561843.
Held F, Kalluri SR, Berthele A, Klein AK, Reindl M, Hemmer B (2021). Frequency of myelin oligodendrocyte glycoprotein antibodies in a large cohort of neurological patients. Mult Scler J Exp Transl Clin. 2021 Jun 25;7(2):20552173211022767. doi: 10.1177/20552173211022767. PMID: 34262784; PMCID: PMC8246507.
Hiltensperger M, Beltrán E, Kant R, Tyystjärvi S, Lepennetier G, Domínguez Moreno H, Bauer IJ, Grassmann S, Jarosch S, Schober K, Buchholz VR, Kenet S, Gasperi C, Öllinger R, Rad R, Muschaweckh A, Sie C, Aly L, Knier B, Garg G, Afzali AM, Gerdes LA, Kümpfel T, Franzenburg S, Kawakami N, Hemmer B, Busch DH, Misgeld T, Dornmair K, Korn T (2021). Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity. Nat Immunol. 2021 Jun 7. doi: 10.1038/s41590-021-00948-8. Epub ahead of print. PMID: 34099917.
Laurson-Doube J, Rijke N, Helme A, Baneke P, Banwell B, Viswanathan S, Hemmer B, Yamout B (2021). Ethical use of off-label disease-modifying therapies for multiple sclerosis. Mult Scler. 2021 Jul 26:13524585211030207. doi: 10.1177/13524585211030207. Epub ahead of print. PMID: 34304636.
Marignier R, Hacohen Y, Cobo-Calvo A, Pröbstel AK, Aktas O, Alexopoulos H, Amato MP, Asgari N, Banwell B, Bennett J, Brilot F, Capobianco M, Chitnis T, Ciccarelli O, Deiva K, De Sèze J, Fujihara K, Jacob A, Kim HJ, Kleiter I, Lassmann H, Leite MI, Linington C, Meinl E, Palace J, Paul F, Petzold A, Pittock S, Reindl M, Sato DK, Selmaj K, Siva A, Stankoff B, Tintore M, Traboulsee A, Waters P, Waubant E, Weinshenker B, Derfuss T, Vukusic S, Hemmer B (2021). Myelin-oligodendrocyte glycoprotein antibody-associated disease. Lancet Neurol. 2021 Sep;20(9):762-772. doi: 10.1016/S1474-4422(21)00218-0. PMID: 34418402.
Ostkamp P, Salmen A, Pignolet B, Görlich D, Andlauer TFM, Schulte-Mecklenbeck A, Gonzalez-Escamilla G, Bucciarelli F, Gennero I, Breuer J, Antony G, Schneider-Hohendorf T, Mykicki N, Bayas A, Then Bergh F, Bittner S, Hartung HP, Friese MA, Linker RA, Luessi F, Lehmann-Horn K, Mühlau M, Paul F, Stangel M, Tackenberg B, Tumani H, Warnke C, Weber F, Wildemann B, Zettl UK, Ziemann U, Müller-Myhsok B, Kümpfel T, Klotz L, Meuth SG, Zipp F, Hemmer B, Hohlfeld R, Brassat D, Gold R, Gross CC, Lukas C, Groppa S, Loser K, Wiendl H, Schwab N; German Competence Network Multiple Sclerosis (KKNMS) and the BIONAT Network (2021). Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2018457118. doi: 10.1073/pnas.2018457118. PMID: 33376202.
Portaccio E, Fonderico M, Hemmer B, Derfuss T, Stankoff B, Selmaj K, Tintorè M, Amato MP (2021). Impact of COVID-19 on multiple sclerosis care and management: Results from the European Committee for Treatment and Research in Multiple Sclerosis survey. Mult Scler. 2021 Mar 25:13524585211005339. doi: 10.1177/13524585211005339. Epub ahead of print. PMID: 33764197.
Sullivan R, Kilaru A, Hemmer B, Campbell Cree BA, Greenberg BM, Kundu U, Hach T, DeLasHeras V, Ward BJ, Berger J (2021). COVID-19 Infection in Fingolimod- or Siponimod-Treated Patients: Case Series. Neurol Neuroimmunol Neuroinflamm. 2021 Nov 30;9(1):e1092. doi: 10.1212/NXI.0000000000001092. PMID: 34848501.
Vandebergh M, Andlauer TFM, Zhou Y, Mallants K, Held F, Aly L, Taylor BV, Hemmer B, Dubois B, Goris A (2021). Genetic variation in WNT9B increases relapse hazard in multiple sclerosis. Ann Neurol. 2021 Mar 11. doi: 10.1002/ana.26061. Epub ahead of print. PMID: 33704824.
Wicklein R, Heidegger S, Verbeek M, Eiz-Vesper B, Maecker-Kolhoff B, Kirschke JS, Page A, Korn T, Hemmer B, Deschauer M (2021). Combined Treatment With Pembrolizumab and Allogenic BK Virus-Specific T Cells in Progressive Multifocal Leukoencephalopathy: A Case Report. Neurol Neuroimmunol Neuroinflamm. 2021 Jul 20;8(5):e1042. doi: 10.1212/NXI.0000000000001042. PMID: 34285093; PMCID: PMC8293283.
Wicklein R, Wauschkuhn J, Giglhuber K, Kümpfel T, Hemmer B, Havla J, Knier B (2021). Association of Peripapillary Hyper-Reflective Ovoid Masslike Structures and Disease Duration in Primary Progressive Multiple Sclerosis. Eur J Neurol. 2021 Aug 9. doi: 10.1111/ene.15056. Epub ahead of print. PMID: 34374178.

Aly L, Havla J, Lepennetier G, Andlauer TFM, Sie C, Strauß EM, Hoshi MM, Kümpfel T, Hiltensperger M, Mitsdoerffer M, Mühlau M, Zimmer C, Hemmer B, Korn T, Knier B (2020). Inner retinal layer thinning in radiologically isolated syndrome predicts conversion to multiple sclerosis. Eur J Neurol. 2020;10.1111/ene.14416. doi:10.1111/ene.14416 [published online ahead of print, 2020 Jun 26].
Andlauer TFM, Link J, Martin D, Ryner M, Hermanrud C, Grummel V, Auer M, Hegen H, Aly L, Gasperi C, Knier B, Müller-Myhsok B, Jensen PEH, Sellebjerg F, Kockum I, Olsson T, Pallardy M, Spindeldreher S, Deisenhammer F, Fogdell-Hahn A, Hemmer B; ABIRISK consortium (2020). Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. BMC Med. 2020 Nov 4;18(1):298. doi: 10.1186/s12916-020-01769-6. PMID: 33143745; PMCID: PMC7641861.
Arloth J, Eraslan G, Andlauer TFM, Martins J, Iurato S, Kühnel B, Waldenberger M, Frank J, Gold R, Hemmer B, Luessi F, Nischwitz S, Paul F, Wiendl H, Gieger C, Heilmann-Heimbach S, Kacprowski T, Laudes M, Meitinger T, Peters A, Rawal R, Strauch K, Lucae S, Müller-Myhsok B, Rietschel M, Theis FJ, Binder EB, Mueller NS (2020). DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning. PLoS Comput Biol. 2020 Feb 3;16(2):e1007616. doi: 10.1371/journal.pcbi.1007616. eCollection 2020 Feb.
Arrambide G, Iacobaeus E, Amato MP, Derfuss T, Vukusic S, Hemmer B, Brundin L, Tintore M (2020). Aggressive multiple sclerosis (2): Treatment. Mult Scler. 2020;1352458520924595. doi:10.1177/1352458520924595 [published online ahead of print, 2020 Jun 12]
Bian Y, Zheng R, Bayer FP, Wong C, Chang YC, Meng C, Zolg DP, Reinecke M, Zecha J, Wiechmann S, Heinzlmeir S, Scherr J, Hemmer B, Baynham M, Gingras AC, Boychenko O, Kuster B (2020). Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC-MS/MS. Nat Commun. 2020 Jan 9;11(1):157. doi: 10.1038/s41467-019-13973-x.
Bittner S, Steffen F, Uphaus T, Muthuraman M, Fleischer V, Salmen A, Luessi F, Berthele A, Klotz L, Meuth SG, Bayas A, Paul F, Hartung HP, Linker R, Heesen C, Stangel M, Wildemann B, Then Bergh F, Tackenberg B, Kuempfel T, Weber F, Zettl UK, Ziemann U, Tumani H, Groppa S, Mühlau M, Lukas C, Hemmer B, Wiendl H, Gold R, Zipp F (2020). Clinical implications of serum neurofilament in newly diagnosed MS patients: A longitudinal multicentre cohort study. EBioMedicine. 2020;56:102807. doi:10.1016/j.ebiom.2020.102807 [published online ahead of print, 2020 May 24]
Cortese M, Munger KL, Martínez-Lapiscina EH, Barro C, Edan G, Freedman MS, Hartung HP, Montalbán X, Foley FW, Penner IK, Hemmer B, Fox EJ, Schippling S, Wicklein EM, Kappos L, Kuhle J, Ascherio A; BENEFIT Study Group (2020). Vitamin D, smoking, EBV, and long-term cognitive performance in MS: 11-year follow-up of BENEFIT. Neurology. 2020 Apr 16. pii: 10.1212/WNL.0000000000009371. doi: 10.1212/WNL.0000000000009371. [Epub ahead of print]
Engl C, Tiemann L, Grahl S, Bussas M, Schmidt P, Pongratz V, Berthele A, Beer A, Gaser C, Kirschke JS, Zimmer C, Hemmer B, Mühlau M (2020). Cognitive impairment in early MS: contribution of white matter lesions, deep grey matter atrophy, and cortical atrophy. J Neurol. 2020 Apr 23. doi: 10.1007/s00415-020-09841-0. [Epub ahead of print]
Gasperi C, Andlauer TFM, Keating A, Knier B, Klein A, Pernpeintner V, Lichtner P, Gold R, Zipp F, Then Bergh F, Stangel M, Tumani H, Wildemann B, Wiendl H, Bayas A, Kümpfel T, Zettl UK, Linker RA, Ziemann U, Knop M, Warnke C, Friese MA, Paul F, Tackenberg B, Berthele A, Hemmer B (2020). Genetic determinants of the humoral immune response in MS. Neurol Neuroimmunol Neuroinflamm. 2020;7(5):e827. Published 2020 Jul 16. doi:10.1212/NXI.0000000000000827
Grahl S, Bussas M, Pongratz V, Kirschke JS, Zimmer C, Berthele A, Hemmer B, Mühlau M (2020). T1-Weighted Intensity Increase After a Single Administration of a Linear Gadolinium-Based Contrast Agent in Multiple Sclerosis. Clin Neuroradiol. 2020 Feb 13. doi: 10.1007/s00062-020-00882-6. [Epub ahead of print]
Hässler S, Bachelet D, Duhaze J, Szely N, Gleizes A, Hacein-Bey Abina S, Aktas O, Auer M, Avouac J, Birchler M, Bouhnik Y, Brocq O, Buck-Martin D, Cadiot G, Carbonnel F, Chowers Y, Comabella M, Derfuss T, De Vries N, Donnellan N, Doukani A, Guger M, Hartung HP, Kubala Havrdova E, Hemmer B, Huizinga T, Ingenhoven K, Hyldgaard-Jensen PE, Jury EC, Khalil M, Kieseier B, Laurén A, Lindberg R, Loercher A, Maggi E, Manson J, Mauri C, Mohand Oumoussa B, Montalban X, Nachury M, Nytrova P, Richez C, Ryner M, Sellebjerg F, Sievers C, Sikkema D, Soubrier M, Tourdot S, Trang C, Vultaggio A, Warnke C, Spindeldreher S, Dönnes P, Hickling TP, Hincelin Mery A, Allez M, Deisenhammer F, Fogdell-Hahn A, Mariette X, Pallardy M, Broët P; ABIRISK consortium (2020). Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium. PLoS Med. 2020 Oct 30;17(10):e1003348. doi: 10.1371/journal.pmed.1003348. PMID: 33125391.
Heitmann H, Andlauer TFM, Korn T, Mühlau M, Henningsen P, Hemmer B, Ploner M (2020). Fatigue, depression, and pain in multiple sclerosis: How neuroinflammation translates into dysfunctional reward processing and anhedonic symptoms. Mult Scler. 2020 Nov 12:1352458520972279. doi: 10.1177/1352458520972279. Epub ahead of print. PMID: 33179588.
Heitmann H, Haller B, Tiemann L, Mühlau M, Berthele A, Tölle TR, Salmen A, Ambrosius B, Bayas A, Asseyer S, Hartung HP, Heesen C, Stangel M, Wildemann B, Haars S, Groppa S, Luessi F, Kümpfel T, Nischwitz S, Meuth SG, Klotz L, Linker RA, Zettl UK, Ziemann U, Tumani H, Tackenberg B, Zipp F, Wiendl H, Gold R, Hemmer B, Ploner M (2020). Longitudinal prevalence and determinants of pain in multiple sclerosis: results from the German National Multiple Sclerosis Cohort study. Pain. 2020 Apr;161(4):787-796. doi: 10.1097/j.pain.0000000000001767.
Iacobaeus E, Arrambide G, Pia Amato M, Derfuss T, Vukusic S, Hemmer B, Tintore M, Brundin L (2020). Aggressive multiple sclerosis (1): Towards a definition of the phenotype. Mult Scler. 2020;1352458520925369. doi:10.1177/135245852092536 9[published online ahead of print, 2020 Jun 12]
Ikenberg B, Hemmer B, Dommasch M, Kanz KG, Wunderlich S, Knier B (2020). Code Stroke Patient Referral by Emergency Medical Services During the Public COVID-19 Pandemic Lockdown. J Stroke Cerebrovasc Dis. 2020 Nov;29(11):105175. doi: 10.1016/j.jstrokecerebrovasdis.2020.105175. Epub 2020 Jul 21. PMID: 33066900; PMCID: PMC7373060.
Kemmerer CL, Pernpeintner V, Ruschil C, Abdelhak A, Scholl M, Ziemann U, Krumbholz M, Hemmer B, Kowarik MC (2020). Differential effects of disease modifying drugs on peripheral blood B cell subsets: A cross sectional study in multiple sclerosis patients treated with interferon-β, glatiramer acetate, dimethyl fumarate, fingolimod or natalizumab. PLoS One. 2020;15(7):e0235449. Published 2020 Jul 27. doi:10.1371/journal.pone.0235449
Killestein J, Du Pasquier R, Hemmer B (2020). Vaccination in B-cell depleted MS patients. Neurology. 2020;10.1212/WNL.0000000000010378. doi:10.1212/WNL.0000000000010378 [published online ahead of print, 2020 Jul 29]
Kowarik MC, Astling D, Lepennetier G, Ritchie A, Hemmer B, Owens GP, Bennett JL (2020). Differential Effects of Fingolimod and Natalizumab on B Cell Repertoires in Multiple Sclerosis Patients. Neurotherapeutics. 2020 Nov 30. doi: 10.1007/s13311-020-00975-7. Epub ahead of print. PMID: 33258072.
Neumann B, Schmidbauer ML, Dimitriadis K, Otto S, Knier B, Niesen WD, Hosp JA, Günther A, Lindemann S, Nagy G, Steinberg T, Linker RA, Hemmer B, Bösel J (2020). Cerebrospinal fluid findings in COVID-19 patients with neurological symptoms. J Neurol Sci. 2020;418:117090. doi:10.1016/j.jns.2020.117090 [published online ahead of print, 2020 Aug 11]
Ruschil C, Gabernet G, Lepennetier G, Heumos S, Kaminski M, Hracsko Z, Irmler M, Beckers J, Ziemann U, Nahnsen S, Owens GP, Bennett JL, Hemmer B, Kowarik MC (2020). Specific Induction of Double Negative B Cells During Protective and Pathogenic Immune Responses. Front Immunol. 2020 Dec 18;11:606338. doi: 10.3389/fimmu.2020.606338. PMID: 33391273; PMCID: PMC7775384.
Tsaktanis T, Beyer T, Nirschl L, Linnerbauer M, Grummel V, Bussas M, Tjon E, Mühlau M, Korn T, Hemmer B, Quintana FJ, Rothhammer V (2020). Aryl Hydrocarbon Receptor Plasma Agonist Activity Correlates With Disease Activity in Progressive MS. Neurol Neuroimmunol Neuroinflamm. 2020 Dec 24;8(2):e933. doi: 10.1212/NXI.0000000000000933. PMID: 33361385.
Whittam DH, Karthikeayan V, Gibbons E, Kneen R, Chandratre S, Ciccarelli O, Hacohen Y, de Seze J, Deiva K, Hintzen RQ, Wildemann B, Jarius S, Kleiter I, Rostasy K, Huppke P, Hemmer B, Paul F, Aktas O, Pröbstel AK, Arrambide G, Tintore M, Amato MP, Nosadini M, Mancardi MM, Capobianco M, Illes Z, Siva A, Altintas A, Akman-Demir G, Pandit L, Apiwattankul M, Hor JY, Viswanathan S, Qiu W, Kim HJ, Nakashima I, Fujihara K, Ramanathan S, Dale RC, Boggild M, Broadley S, Lana-Peixoto MA, Sato DK, Tenembaum S, Cabre P, Wingerchuk DM, Weinshenker BG, Greenberg B, Matiello M, Klawiter EC, Bennett JL, Wallach AI, Kister I, Banwell BL, Traboulsee A, Pohl D, Palace J, Leite MI (2020). Treatment of MOG antibody associated disorders: results of an international survey. J Neurol. 2020;10.1007/s00415-020-10026-y. doi:10.1007/s00415-020-10026-y [published online ahead of print, 2020 Jul 4]

Alexopoulos P, Thierjung N, Economou P, Werle L, Buhl F, Kagerbauer S, Papanastasiou AD, Grimmer T, Gourzis P, Berthele A, Hemmer B, Kübler H, Martin J, Politis A, Perneczky R (2019). Plasma Levels of Soluble AβPPβ as a Biomarker for Alzheimer's Disease with Dementia. J Alzheimers Dis. 2019 Mar 18. doi: 10.3233/JAD-181088. [Epub ahead of print]
Ancau M, Berthele A, Hemmer B (2019). CD20 monoclonal antibodies for the treatment of multiple sclerosis: up-to-date. Expert Opin Biol Ther. 2019 Apr 26. doi: 10.1080/14712598.2019.1611778. [Epub ahead of print]
Bittner S, Engel S, Lange C, Weber MS, Haghikia A, Luessi F, Korn T, Klotz L, Bayas A, Paul F, Heesen C, Stangel M, Wildemann B, Bergh FT, Tackenberg B, Trebst C, Warnke C, Linker R, Kerschensteiner M, Zettl U, Tumani H, Brück W, Meuth SG, Kümpfel T, Hemmer B, Wiendl H, Gold R, Zipp F (2019). [Article in German] [Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : Current status and recommeExpression by Hippocampal Interneurons in the Tg2576 Mouse Model of Alzheimer’s Disease. Nervenarzt. 2019 Jul 11. doi: 10.1007/s00115-019-0760-0. [Epub ahead of print]
Eichinger P, Schön S, Pongratz V, Wiestler H, Zhang H, Bussas M, Hoshi MM, Kirschke J, Berthele A, Zimmer C, Hemmer B, Mühlau M, Wiestler B (2019). Accuracy of Unenhanced MRI in the Detection of New Brain Lesions in Multiple Sclerosis. 2019 Mar 12:181568. doi: 10.1148/radiol.2019181568. [Epub ahead of print]
Gasperi C, Salmen A, Antony G, Bayas A, Heesen C, Kümpfel T, Linker RA, Paul F, Stangel M, Tackenberg B, Bergh FT, Warnke C, Weber F, Wiendl H, Wildemann B, Zettl UK, Ziemann U, Zipp F, Tumani H, Gold R, Hemmer B; German Competence Network of Multiple Sclerosis (2019). Association of Intrathecal Immunoglobulin G Synthesis With Disability Worsening in Multiple Sclerosis. JAMA Neurol. 2019 Apr 29. doi: 10.1001/jamaneurol.2019.0905. [Epub ahead of print]
Grahl S, Pongratz V, Schmidt P, Engl C, Bussas M, Radetz A, Gonzalez-Escamilla G, Groppa S, Zipp F, Lukas C, Kirschke J, Zimmer C, Hoshi M, Berthele A, Hemmer B, Mühlau M (2019). Evidence for a white matter lesion size threshold to support the diagnosis of relapsing remitting multiple sclerosis. Mult Scler Relat Disord. 2019 Jan 28;29:124-129. doi: 10.1016/j.msard.2019.01.042. [Epub ahead of print]
Hapfelmeier A, Gasperi C, Donnachie E, Hemmer B (2019). A large case-control study on vaccination as risk factor for multiple sclerosis. Neurology. 2019 Jul 30. pii: 10.1212/WNL.0000000000008012. doi: 10.1212/WNL.0000000000008012. [Epub ahead of print]
International Multiple Sclerosis Genetics Consortium [i.a. Hemmer B] (2019). A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis. Nat Commun. 2019 May 20;10(1):2236. doi: 10.1038/s41467-019-09773-y.
International Multiple Sclerosis Genetics Consortium [i.a. Hemmer B, Korn T] (2019). Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility. Science. 2019 Sep 27;365(6460). pii: eaav7188. doi: 10.1126/science.aav7188.
Klein A, Selter RC, Hapfelmeier A, Berthele A, Müller-Myhsok B, Pongratz V, Gasperi C, Zimmer C, Mühlau M, Hemmer B (2019). CSF parameters associated with early MRI activity in patients with MS. Neurol Neuroimmunol Neuroinflamm. 2019 May 30;6(4):e573. doi: 10.1212/NXI.0000000000000573. eCollection 2019 Jul.
Lepennetier G, Hracsko Z, Unger M, Van Griensven M, Grummel V, Krumbholz M, Berthele A, Hemmer B, Kowarik MC (2019). Cytokine and immune cell profiling in the cerebrospinal fluid of patients with neuro-inflammatory diseases. J Neuroinflammation. 2019 Nov 14;16(1):219. doi: 10.1186/s12974-019-1601-6.
Liesche F, Ruf V, Zoubaa S, Kaletka G, Rosati M, Rubbenstroth D, Herden C, Goehring L, Wunderlich S, Wachter MF, Rieder G, Lichtmannegger I, Permanetter W, Heckmann JG, Angstwurm K, Neumann B, Märkl B, Haschka S, Niller HH, Schmidt B, Jantsch J, Brochhausen C, Schlottau K, Ebinger A, Hemmer B, Riemenschneider MJ, Herms J, Beer M, Matiasek K, Schlegel J (2019). The neuropathology of fatal encephalomyelitis in human Borna virus infection. Acta Neuropathol. 2019 Jul 26. doi: 10.1007/s00401-019-02047-3. [Epub ahead of print]
Nolan RC, Liu M, Akhand O, Calabresi PA, Paul F, Petzold A, Balk L, Brandt AU, Martínez-Lapiscina EH, Saidha S, Villoslada P, Al-Hassan AA, Behbehani R, Frohman EM, Frohman T, Havla J, Hemmer B, Jiang H, Knier B, Korn T, Leocani L, Papadopoulou A, Pisa M, Zimmermann H, Galetta SL, Balcer LJ; IMSVISUAL Consortium (2019). Optimal Inter-Eye Difference Thresholds by OCT in MS: An International Study. Ann Neurol. 2019 Mar 9. doi: 10.1002/ana.25462. [Epub ahead of print]
Pongratz V, Schmidt P, Bussas M, Grahl S, Gaser C, Berthele A, Hoshi MM, Kirschke J, Zimmer C, Hemmer B, Mühlau M(2019). Prognostic value of white matter lesion shrinking in early multiple sclerosis: An intuitive or naïve notion? Brain Behav. 2019 Sep 26:e01417. doi: 10.1002/brb3.1417. [Epub ahead of print]
Schmidt P, Pongratz V, Küster P, Meier D, Wuerfel J, Lukas C, Bellenberg B, Zipp F, Groppa S, Sämann PG, Weber F, Gaser C, Franke T, Bussas M, Kirschke J, Zimmer C, Hemmer B, Mühlau M (2019). Automated segmentation of changes in FLAIR-hyperintense white matter lesions in multiple sclerosis on serial magnetic resonance imaging. Neuroimage Clin. 2019 May 2;23:101849. doi: 10.1016/j.nicl.2019.101849. [Epub ahead of print]
Tanti GK, Srivastava R, Kalluri SR, Nowak C, Hemmer B (2019). Isolation, Culture and Functional Characterization of Glia and Endothelial Cells From Adult Pig Brain. Front Cell Neurosci. 2019 Jul 23;13:333. doi: 10.3389/fncel.2019.00333. eCollection 2019.
van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernández I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleó A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illán-Gala I, Wei W, Jeune B, Orellana A, Then Bergh F, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodríguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodríguez Rodríguez E, Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tárraga L, Maier W, Dols-Icardo O, Kawalia A, Dalmasso MC, Boada M, Zettl UK, van Schoor NM, Beekman M, Allen M, Masliah E, de Munain AL, Pantelyat A, Wszolek ZK, Ross OA, Dickson DW, Graff-Radford NR, Knopman D, Rademakers R, Lemstra AW, Pijnenburg YAL, Scheltens P, Gasser T, Chinnery PF, Hemmer B, Huisman MA, Troncoso J, Moreno F, Nohr EA, Sørensen TIA, Heutink P, Sánchez-Juan P, Posthuma D, Clarimón J, Christensen K, Ertekin-Taner N, Scholz SW, Ramirez A, Ruiz A, Slagboom E, van der Flier WM, Holstege H(2019). A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta Neuropathol. 2019 May 27. doi: 10.1007/s00401-019-02026-8. [Epub ahead of print]
Wuschek A, Grahl S, Pongratz V, Korn T, Kirschke J, Zimmer C, Hemmer B, Mühlau M (2019). CSF Protein Concentration Shows No Correlation With Brain Volume Measures. Front Neurol. 2019 May 3;10:463. doi: 10.3389/fneur.2019.00463. eCollection 2019.

Berger JR, Cree BA, Greenberg B, Hemmer B, Ward BJ, Dong VM, Merschhemke M (2018). Progressive multifocal leukoencephalopathy after fingolimod treatment. Neurology. 2018 Apr 18. pii: 10.1212/WNL.0000000000005529. doi: 10.1212/WNL.0000000000005529. [Epub ahead of print]
Buck D, Andlauer TF, Igl W, Wicklein EM, Mühlau M, Weber F, Köchert K, Pohl C, Arnason B, Comi G, Cook S, Filippi M, Hartung HP, Jeffery D, Kappos L, Barkhof F, Edan G, Freedman MS, Montalbán X, Müller-Myhsok B, Hemmer B; BEYOND and BENEFIT Study Groups (2018). Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials. Mult Scler. 2018 Mar 1:1352458518763089. doi: 10.1177/1352458518763089. [Epub ahead of print]
Daltrozzo T, Hapfelmeier A, Donnachie E, Schneider A, Hemmer B. A Systematic Assessment of Prevalence, Incidence and Regional Distribution of Multiple Sclerosis in Bavaria From 2006 to 2015. Front Neurol. 2018 Oct 30;9:871. doi: 10.3389/fneur.2018.00871. PMID: 30425676; PMCID: PMC6218432.
Feucht N, Maier M, Lepennetier G, Pettenkofer M, Wetzlmair C, Daltrozzo T, Scherm P, Zimmer C, Hoshi MM, Hemmer B, Korn T, Knier B (2018). Optical coherence tomography angiography indicates associations of the retinal vascular network and disease activity in multiple sclerosis. Mult Scler. 2018 Jan 1:1352458517750009. doi: 10.1177/1352458517750009. [Epub ahead of print]
Graetz C, Gröger A, Luessi F, Salmen A, Zöller D, Schultz J, Siller N, Fleischer V, Bellenberg B, Berthele A, Biberacher V, Havla J, Hecker M, Hohlfeld R, Infante-Duarte C, Kirschke JS, Kümpfel T, Linker R, Paul F, Pfeuffer S, Sämann P, Toenges G, Weber F, Zettl UK, Jahn-Eimermacher A, Antony G, Groppa S, Wiendl H, Hemmer B, Mühlau M, Lukas C, Gold R, Lill CM, Zipp F (2018). Association of smoking but not HLA-DRB1*15:01, APOE or body mass index with brain atrophy in early multiple sclerosis. Mult Scler. 2018 Mar 1:1352458518763541. doi: 10.1177/1352458518763541. [Epub ahead of print]
Jensen PEH, Warnke C, Ingenhoven K, Piccoli L, Gasis M, Hermanrud C, Fernandez-Rodriguez BM, Ryner M, Kramer D, Link J, Ramanujam R, Auer M, Buck D, Grummel V, Bertotti E, Fissolo N, Oliver-Martos B, Nytrova P, Khalil M, Guger M, Rathmaier S, Sievers-Stober C, Lindberg RLP, Hässler S, Bachelet D, Aktas O, Donnellan N, Lawton A, Hemmer B, Havrdova EK, Kieseier B, Hartung HP, Comabella M, Montalban X, Derfuss T, Sellebjerg F, Dönnes P, Pallardy M, Spindeldreher S, Broët P, Deisenhammer F, Fogdell-Hahn A, Soelberg Sorensen P, On behalf of the ABIRISK Consortiu (2018). Detection and kinetics of persistent neutralizing anti-interferon-beta antibodies in patients with multiple sclerosis. Results from the ABIRISK prospective cohort study. J Neuroimmunol. 2018 Nov 7;326:19-27. doi: 10.1016/j.jneuroim.2018.11.002. [Epub ahead of print]
Johnen A, Bürkner PC, Landmeyer NC, Ambrosius B, Calabrese P, Motte J, Hessler N, Antony G, König IR, Klotz L, Hoshi MM, Aly L, Groppa S, Luessi F, Paul F, Tackenberg B, Bergh FT, Kümpfel T, Tumani H, Stangel M, Weber F, Bayas A, Wildemann B, Heesen C, Zettl UK, Zipp F, Hemmer B, Meuth SG, Gold R, Wiendl H, Salmen A; German Competence Network Multiple Sclerosis (KKNMS) (2018). Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS). J Neurol. 2018 Dec 4. doi: 10.1007/s00415-018-9142-y. [Epub ahead of print]
Kleiter I, Gahlen A, Borisow N, Fischer K, Wernecke KD, Hellwig K, Pache F, Ruprecht K, Havla J, Kümpfel T, Aktas O, Hartung HP, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Stellmann JP, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Krumbholz M, Zeltner L, Ziemann U, Linker R, Schwab M, Marziniak M, Then Bergh F, Hofstadt-van Oy U, Neuhaus O, Zettl UK, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C; NEMOS (Neuromyelitis Optica Study Group) (2018). Apheresis therapies for NMOSD attacks: A retrospective study of 207 therapeutic interventions. Neurol Neuroimmunol Neuroinflamm. 2018 Sep 26;5(6):e504. doi: 10.1212/NXI.0000000000000504. eCollection 2018 Nov.
Knier B, Hiltensperger M, Sie C, Aly L, Lepennetier G, Engleitner T, Garg G, Muschaweckh A, Mitsdörffer M, Koedel U, Höchst B, Knolle P, Gunzer M, Hemmer B, Rad R, Merkler D, Korn T (2018). Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity. Nat Immunol. 2018 Dec;19(12):1341-1351. doi: 10.1038/s41590-018-0237-5. Epub 2018 Oct 29.
Kular L, Liu Y, Ruhrmann S, Zheleznyakova G, Marabita F, Gomez-Cabrero D, James T, Ewing E, Lindén M, Górnikiewicz B, Aeinehband S, Stridh P, Link J, Andlauer TFM, Gasperi C, Wiendl H, Zipp F, Gold R, Tackenberg B, Weber F, Hemmer B, Strauch K, Heilmann-Heimbach S, Rawal R, Schminke U, Schmidt CO, Kacprowski T, Franke A, Laudes M, Dilthey AT, Celius EG, Søndergaard HB, Tegnér J, Harbo HF, Oturai AB, Olafsson S, Eggertsson HP, Halldorsson BV, Hjaltason H, Olafsson E, Jonsdottir I, Stefansson K, Olsson T, Piehl F, Ekström TJ, Kockum I, Feinberg AP, Jagodic M (2018). DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis. Nat Commun. 2018 Jun 19;9(1):2397. doi: 10.1038/s41467-018-04732-5.
Lechner P, Buck D, Sick L, Hemmer B, Multhoff G (2018). Serum heat shock protein 70 levels as a biomarker for inflammatory processes in multiple sclerosis. Mult Scler J Exp Transl Clin. 2018 May 2;4(2):2055217318767192. doi: 10.1177/2055217318767192. eCollection 2018 Apr-Jun.
Montalban X, Gold R, Thompson AJ, Otero-Romero S, Amato MP, Chandraratna D, Clanet M, Comi G, Derfuss T, Fazekas F, Hartung HP, Havrdova E, Hemmer B, Kappos L, Liblau R, Lubetzki C, Marcus E, Miller DH, Olsson T, Pilling S, Selmaj K, Siva A, Sorensen PS, Sormani MP, Thalheim C, Wiendl H, Zipp F (2018). ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis. Mult Scler. 2018 Jan 1:1352458517751049. doi: 10.1177/1352458517751049. [Epub ahead of print]
Thompson AJ, Baranzini SE, Geurts J, Hemmer B, Ciccarelli O (2018). Multiple sclerosis. Lancet. 2018 Mar 22. pii: S0140-6736(18)30481-1. doi: 10.1016/S0140-6736(18)30481-1. [Epub ahead of print]
von Bismarck O, Dankowski T, Ambrosius B, Hessler N, Antony G, Ziegler A, Hoshi MM, Aly L, Luessi F, Groppa S, Klotz L, Meuth SG, Tackenberg B, Stoppe M, Then Bergh F, Tumani H, Kümpfel T, Stangel M, Heesen C, Wildemann B, Paul F, Bayas A, Warnke C, Weber F, Linker RA, Ziemann U, Zettl UK, Zipp F, Wiendl H, Hemmer B, Gold R, Salmen A (2018). Treatment choices and neuropsychological symptoms of a large cohort of early MS. Neurol Neuroimmunol Neuroinflamm. 2018 Mar 1;5(3):e446. doi: 10.1212/NXI.0000000000000446. eCollection 2018 May.
Zimmermann HG, Knier B, Oberwahrenbrock T, Behrens J, Pfuhl C, Aly L, Kaminski M, Hoshi MM, Specovius S, Giess RM, Scheel M, Mühlau M, Bellmann-Strobl J, Ruprecht K, Hemmer B, Korn T, Paul F, Brandt AU (2018). Association of Retinal Ganglion Cell Layer Thickness With Future Disease Activity in Patients With Clinically Isolated Syndrome. JAMA Neurol. 2018 Apr 23. doi: 10.1001/jamaneurol.2018.1011. [Epub ahead of print]

Amato MP, Derfuss T, Hemmer B, Liblau R, Montalban X, Soelberg Sørensen P, Miller DH; 2016 ECTRIMS Focused Workshop Group (i.a. Wekerle H) (2017). Environmental modifiable risk factors for multiple sclerosis: Report from the 2016 ECTRIMS focused workshop. Mult Scler. 2017 Jan 6:1352458516686847. doi: 10.1177/1352458516686847. [Epub ahead of print]
Biberacher V, Schmidt P, Selter RC, Pernpeinter V, Kowarik MC, Knier B, Buck D, Hoshi MM, Korn T, Berthele A, Kirschke JS, Zimmer C, Hemmer B, Mühlau M (2017). Fatigue in multiple sclerosis: Associations with clinical, MRI and CSF parameters. Mult Scler. 2017 May 1:1352458517712078. doi: 10.1177/1352458517712078. [Epub ahead of print]
Engelborghs S, Niemantsverdriet E, Struyfs H, Blennow K, Brouns R, Comabella M, Dujmovic I, van der Flier W, Frölich L, Galimberti D, Gnanapavan S, Hemmer B, Hoff E, Hort J, Iacobaeus E, Ingelsson M, Jan de Jong F, Jonsson M, Khalil M, Kuhle J, Lleó A, de Mendonça A, Molinuevo JL, Nagels G, Paquet C, Parnetti L, Roks G, Rosa-Neto P, Scheltens P, Skårsgard C, Stomrud E, Tumani H, Visser PJ, Wallin A, Winblad B, Zetterberg H3,39, Duits F7, Teunissen CE36 (2017). Consensus guidelines for lumbar puncture in patients with neurological diseases. Alzheimers Dement (Amst). 2017 May 18;8:111-126. doi: 10.1016/j.dadm.2017.04.007. eCollection 2017.
Hemmer B, Mühlau M (2017). Multiple sclerosis in 2016: Immune-directed therapies in MS — efficacy and limitations. Nat Rev Neurol. 2017 Feb;13(2):72-74. doi: 10.1038/nrneurol.2017.2. Epub 2017 Jan 20.
Herwerth M, Hemmer B (2017). Daclizumab for the treatment of relapsing-remitting multiple sclerosis. Expert Opin Biol Ther. 2017 Mar 13. doi: 10.1080/14712598.2017.1304913. [Epub ahead of print]
Kalluri SR, Grummel V, Hracsko Z, Pongratz V, Pernpeintner V, Gasperi C, Buck D, Hemmer B; ABIRISK Consortium(2017). Interferon-beta specific T cells are associated with the development of neutralizing antibodies in interferon-beta treated multiple sclerosis patients. J Autoimmun. 2017 Oct 20. pii: S0896-8411(17)30587-5. doi: 10.1016/j.jaut.2017.10.003. [Epub ahead of print]
Kaminski M, Grummel V, Hoffmann D, Berthele A, Hemmer B (2017). The spectrum of aseptic central nervous system infections in southern Germany - demographic, clinical and laboratory findings. Eur J Neurol. 2017 Jun 21. doi: 10.1111/ene.13335. [Epub ahead of print]
Knier B, Leppenetier G, Wetzlmair C, Aly L, Hoshi MM, Pernpeintner V, Biberacher V, Berthele A, Mühlau M, Zimmer C, Hemmer B, Korn T (2017). Association of Retinal Architecture, Intrathecal Immunity, and Clinical Course in Multiple Sclerosis. JAMA Neurol. 2017 May 1. doi: 10.1001/jamaneurol.2017.0377. [Epub ahead of print]
Kowarik MC, Astling D, Gasperi C, Wemlinger S, Schumann H, Dzieciatkowska M, Ritchie AM, Hemmer B, Owens GP, Bennett JL (2017). CNS Aquaporin-4-specific B cells connect with multiple B-cell compartments in neuromyelitis optica spectrum disorder. Ann Clin Transl Neurol. 2017 May 9;4(6):369-380. doi: 10.1002/acn3.418. eCollection 2017 Jun.
Righart R, Schmidt P, Dahnke R, Biberacher V, Beer A, Buck D, Hemmer B, Kirschke JS, Zimmer C, Gaser C, Mühlau M(2017). Volume versus surface-based cortical thickness measurements: A comparative study with healthy controls and multiple sclerosis patients. PLoS One. 2017 Jul 6;12(7):e0179590. doi: 10.1371/journal.pone.0179590. eCollection 2017.
Righart R, Biberacher V, Jonkman LE, Klaver R, Schmidt P, Buck D, Berthele A, Kirschke JS, Zimmer C, Hemmer B, Geurts JJ, Mühlau M (2017). Cortical pathology in MS detected by the T1/T2-weighted ratio from routine MRI. Ann Neurol. 2017 Aug 18. doi: 10.1002/ana.25020. [Epub ahead of print]
Stellmann JP, Krumbholz M, Friede T, Gahlen A, Borisow N, Fischer K, Hellwig K, Pache F, Ruprecht K, Havla J, Kümpfel T, Aktas O, Hartung HP, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Young KL, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Zeltner L, Ziemann U, Linker RA, Schwab M, Marziniak M, Then Bergh F, Hofstadt-van Oy U, Neuhaus O, Zettl U, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C, Kleiter I; NEMOS (Neuromyelitis Optica Study Group) (2017). Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response. J Neurol Neurosurg Psychiatry. 2017 Jun 1. pii: jnnp-2017-315603. doi: 10.1136/jnnp-2017-315603. [Epub ahead of print]

Andlauer T F M, Buck D, Antony G, Bayas A, Bechmann L, Berthele A, Chan A, Gasperi C, Gold R, Graetz C, Haas J, Hecker M, Infante-Durante C, Knop M, Kümpfel T, Limmroth V, Linker R A, Loleit V, Luessi F, Meuth S G, Mühlau M, Nischwitz S, Paul F, Pütz M, Ruck T, Salmen A, Stangel M, Stellmann J-P, Stürner K H, Tackenberg B, Then Bergh F, Tumani H, Warnke C, Weber F, Wiendl H, Wildemann B, Zettl U K, Ziemann U, Zipp F, Arloth J, Weber P, Radivojkov-Blagojevic M, Scheinhardt M O, Dankowski T, Bettecken T, Lichtner P, Czamara D, Carrillo-Roa T, Binder E B, Berger K, Bertram L, Franke A, Gieger C, Herma S, Homuth G, Ising M, Jöckel K-H, Kacprowski T, Kloiber S, Lauder M, Lieb W, Lill C M, Lucae S, Meitinger T, Moebus S, Müller-Nurasyid M, Nöthen M M, Petersmann A, Rawal R, Schminke U, Strauch K, Völzke H, Waldenberger M, Jürgen W, Porcu E, Mulas A, Pitzalis M, Sidore C, Zara I, Cucca F, Zoledziewska M, Ziegler A, Hemmer B, Müller-Myhsok B (2016). Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation. Science Advances. 2016 June 17. 2(6):e1501678. DOI: 10.1126/sciadv.1501678. eCollection 2016.
Bachelet D, Hässler S, Mbogning C, Link J, Ryner M, Ramanujam R, Auer M, Hyldgaard Jensen PE, Koch-Henriksen N, Warnke C, Ingenhoven K, Buck D, Grummel V, Lawton A, Donnellan N, Hincelin-Mery A, Sikkema D, Pallardy M, Kieseier B, Hemmer B, Hartung HP, Soelberg Sorensen P, Deisenhammer F, Dönnes P, Davidson J, Fogdell-Hahn A, Broët P(2016). Occurrence of Anti-Drug Antibodies against Interferon-Beta and Natalizumab in Multiple Sclerosis: A Collaborative Cohort Analysis. PLoS One. 2016 Nov 2;11(11):e0162752. doi: 10.1371/journal.pone.0162752. eCollection 2016.
Beer A, Biberacher V, Schmidt P, Righart R, Buck D, Berthele A, Kirschke J, Zimmer C, Hemmer B, Mühlau M (2016). Tissue damage within normal appearing white matter in early multiple sclerosis: assessment by the ratio of T1- and T2-weighted MR image intensity. Journal of Neurology. 2016 May 13. DOI: 10.1007/s00415-016-8156-6. [Epub ahead of print]
Biberacher V, Schmidt P, Keshavan A, Boucard CC, Righart R, Sämann P, Preibisch C, Fröbel D, Aly L, Hemmer B, Zimmer C, Henry RG, Mühlau M. (2016). Intra- and interscanner variability of magnetic resonance imaging based volumetry in multiple sclerosis. NeuroImage. 2016 July 15. pii: S1053-8119(16)30342-1. DOI: 10.1016/j.neuroimage.2016.07.035. [Epub ahead of print]
Borisow N, Kleiter I, Gahlen A, Fischer K, Wernecke KD, Pache F, Ruprecht K, Havla J, Krumbholz M, Kümpfel T, Aktas O, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Weissert R, Stellmann JP, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Zeltner L, Ziemann U, Linker RA, Schwab M, Marziniak M, Then Bergh F, Hofstadt-van Oy U, Neuhaus O, Winkelmann A, Marouf W, Rückriem L, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C, Hellwig K; NEMOS (Neuromyelitis Optica Study Group) (2016). Influence of female sex and fertile age on neuromyelitis optica spectrum disorders. Mult Scler. 2016 Oct 6. pii: 1352458516671203. [Epub ahead of print]
Gasperi C, Stüve O, Hemmer B (2016). B cell-directed therapies in multiple sclerosis. Neurodegener Dis Manag. 2016 Feb;6(1):37-47. doi: 10.2217/nmt.15.67.
Haass C, Neumann M (2016). Frontotemporal dementia: from molecular mechanisms to therapy. J Neurochem. 2016 Aug;138 Suppl 1:3-5. doi: 10.1111/jnc.13619.
Hauser SL, Bar-Or A, Comi G, Giovannoni G, Hartung HP, Hemmer B, Lublin F, Montalban X, Rammohan KW, Selmaj K, Traboulsee A, Wolinsky JS, Arnold DL, Klingelschmitt G, Masterman D, Fontoura P, Belachew S, Chin P, Mairon N, Garren H, Kappos L; OPERA I and OPERA II Clinical Investigators (2016). Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis. N Engl J Med. 2016 Dec 21. doi: 10.1056/NEJMoa1601277. [Epub ahead of print]
Heink S, Yogev N, Garbers C, Herwerth M, Aly L, Gasperi C, Husterer V, Croxford AL, Möller-Hackbarth K, Bartsch HS, Sotlar K, Krebs S, Regen T, Blum H, Hemmer B, Misgeld T, Wunderlich TF, Hidalgo J, Oukka M, Rose-John S, Schmidt-Supprian M, Waisman A, Korn T (2016). Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells. Nat Immunol. 2016 Nov 28. doi: 10.1038/ni.3632. [Epub ahead of print]
Herwerth M, Kalluri SR, Srivastava R, Kleele T, Kenet S, Illes Z, Merkler D, Bennett JL, Misgeld T, Hemmer B (2016). In vivo imaging reveals rapid astrocyte depletion and axon damage in a model of neuromyelitis optica-related pathology. Ann Neurol. 2016 Mar 6. doi: 10.1002/ana.24630. [Epub ahead of print]
Herwerth M, Prothmann, S Kreiser K, Hemmer B, Ploner M (2016). Spontaneous cerebrospinal fluid leak with venous engorgement mimicking a contrast-enhancing cervical mass. JAMA Neurology. 2016 May 31. DOI: 10.1001/jamaneurol.2016.0277. [Epub ahead of print]
Hucke S, Herold M, Liebmann M, Freise N, Lindner M, Fleck A-K, Zenker S, Thiebes S, Fernandez-Orth J, Buck D, Luessi F, Meuth S G, Zipp F, Hemmer B, Engel D R, Roth J, Kuhlmann T, Heinz W, Klotz (2016). The farnesoid-X-receptor in myeloid cells controls CNS autoimmunity in an IL-10-dependent fashion. Acta Neuropathologica. 2016 July 6. DOI: 10.1007/s00401-016-1593-6. [Epub ahead of print]
Keshavan A, Paul F, Beyer MK, Zhu AH, Papinutto N, Shinohara RT, Stern W, Amann M, Bakshi R, Bischof A, Carriero A, Comabella M, Crane JC, D'Alfonso S, Demaerel P, Dubois B, Filippi M, Fleischer V, Fontaine B, Gaetano L, Goris A, Graetz C, Gröger A, Groppa S, Hafler DA, Harbo HF, Hemmer B, Jordan K, Kappos L, Kirkish G, Llufriu S, Magon S, Martinelli-Boneschi F, McCauley J, Montalban X, Mühlau M, Pelletier D, Pattany PM, Pericak-Vance M, Rebeix I, Rocca M, Rovira A, Schlaeger R, Villoslada P, Wattjes MP, Weiner H, Wuerfel J, Zimmer C, Zipp F; International Multiple Sclerosis Genetics Consortium, Hauser S, Oksenberg JR, Henry RG (2016). Power estimation for non-standardized multisite studies. Neuroimage. 2016 Apr 1. pii: S1053-8119(16)00256-1. doi: 10.1016/j.neuroimage.2016.03.051. [Epub ahead of print]
Knier B, Schmidt P, Aly L, Buck D, Berthele A, Mühlau M, Zimmer C, Hemmer B, Korn T (2016). Retinal inner nuclear layer volume reflects response to immunotherapy in multiple sclerosis. Brain. 2016 Aug 30. pii: aww219. [Epub ahead of print]
Kowarik MC, Hoshi M, Hemmer B, Berthele A (2016). Failure of alemtuzumab as a rescue in a NMOSD patient treated with rituximab. Neurol Neuroimmunol Neuroinflamm. 2016 Feb 10;3(2):e208. doi: 10.1212/NXI.0000000000000208. eCollection 2016.
Lehmann-Horn K, Horst P, Grein P, Leppmeier U, Teuber-Hanselmann S, Hemmer B, Berthele A (2016). PML during dimethyl fumarate treatment of multiple sclerosis: how does lymphopenia matter? Neurology. 2016 June 24. DOI: http://dx.doi.org/10.1212/WNL.0000000000002900. pii: 10.1212/WNL.0000000000002900. [Epub ahead of print]
Montalban X, Hauser SL, Kappos L, Arnold DL, Bar-Or A, Comi G, de Seze J, Giovannoni G, Hartung HP, Hemmer B, Lublin F, Rammohan KW, Selmaj K, Traboulsee A, Sauter A, Masterman D, Fontoura P, Belachew S, Garren H, Mairon N, Chin P, Wolinsky JS; ORATORIO Clinical Investigators (2016). Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis. N Engl J Med. 2016 Dec 21. doi: 10.1056/NEJMoa1606468. [Epub ahead of print]
Mühlau M, Andlauer TF, Hemmer B (2016). HLA Genetic Risk Burden in Multiple Sclerosis. JAMA Neurol. 2016 Oct 24. doi: 10.1001/jamaneurol.2016.4329.
Schirmer L, Worthington V, Solloch U, Loleit V, Grummel V, Lakdawala N, Grant D, Wassmuth R, Schmidt AH, Gebhardt F, Andlauer TF, Sauter J, Berthele A, Lunn MP, Hemmer B (2016). Higher frequencies of HLA DQB1*05:01 and anti-glycosphingolipid antibodies in a cluster of severe Guillain-Barré syndrome. J Neurol. 2016 Aug 2. [Epub ahead of print]

Bennett JL, O'Connor KC, Bar-Or A, Zamvil SS, Hemmer B, Tedder TF, von Büdingen HC, Stuve O, Yeaman MR, Smith TJ, Stadelmann C (2015). B lymphocytes in neuromyelitis optica. Neurol Neuroimmunol Neuroinflamm. 2015 May 7;2(3):e104. doi: 10.1212/NXI.0000000000000104. eCollection 2015.
Dankowski T, Buck D, Andlauer TF, Antony G, Bayas A, Bechmann L, Berthele A, Bettecken T, Chan A, Franke A, Gold R, Graetz C, Haas J, Hecker M, Herms S, Infante-Duarte C, Jöckel KH, Kieseier BC, Knier B, Knop M, Kümpfel T, Lichtner P, Lieb W, Lill CM, Limmroth V, Linker RA, Loleit V, Meuth SG, Moebus S, Müller-Myhsok B, Nischwitz S, Nöthen MM, Paul F, Pütz M, Ruck T, Salmen A, Stangel M, Stellmann JP, Strauch K, Stürner KH, Tackenberg B, Then Bergh F, Tumani H, Waldenberger M, Weber F, Wiendl H, Wildemann B, Zettl UK, Ziemann U, Zipp F, Hemmer B, Ziegler A; German Competence Network for Multiple Sclerosis (KKNMS) (2015). Successful replication of GWAS hits for multiple sclerosis in 10,000 Germans using the exome array. Genet Epidemiol. 2015 Oct 26. doi: 10.1002/gepi.21933. [Epub ahead of print]
Goris A, Pauwels I, Gustavsen MW, van Son B, Hilven K, Bos SD, Celius EG, Berg-Hansen P, Aarseth J, Myhr KM, D'Alfonso S, Barizzone N, Leone MA, Martinelli Boneschi F, Sorosina M, Liberatore G, Kockum I, Olsson T, Hillert J, Alfredsson L, Bedri SK, Hemmer B, Buck D, Berthele A, Knier B, Biberacher V, van Pesch V, Sindic C, Bang Oturai A, Søndergaard HB, Sellebjerg F, Jensen PE, Comabella M, Montalban X, Pérez-Boza J, Malhotra S, Lechner-Scott J, Broadley S, Slee M, Taylor B, Kermode AG, Gourraud PA; International Multiple Sclerosis Genetics Consortium, Sawcer SJ, Andreassen BK, Dubois B, Harbo HF (2015). Genetic variants are major determinants of CSF antibody levels in multiple sclerosis. Brain. 2015 Jan 22. pii: awu405. [Epub ahead of print]
Heitmann H, Biberacher V, Tiemann L, Buck D, Loleit V, Selter RC, Knier B, Tölle TR, Mühlau M, Berthele A, Hemmer B, Ploner M (2015). Prevalence of neuropathic pain in early multiple sclerosis. Mult Scler. 2015 Oct 19. pii: 1352458515613643. [Epub ahead of print]
Hemmer B (2015). Antibodies to the inward rectifying potassium channel 4.1 in multiple sclerosis: different methodologies--conflicting results? Mult Scler. 2015 Jan 12. pii: 1352458514564493. [Epub ahead of print]
Hemmer B, Kerschensteiner M, Korn T (2015). Role of the innate and adaptive immune responses in the course of multiple sclerosis. Lancet Neurol. 2015 Apr;14(4):406-419. doi: 10.1016/S1474-4422(14)70305-9.
International Multiple Sclerosis Genetics Consortium; International IBD Genetics Consortium (IIBDGC) , ( i.a. Winkelmann J, Hemmer B) (2015). Class II HLA interactions modulate genetic risk for multiple sclerosis. Nat Genet. 2015 Sep 7. doi: 10.1038/ng.3395. [Epub ahead of print]
Kleiter I, Gahlen A, Borisow N, Fischer K, Wernecke KD, Wegner B, Hellwig K, Pache F, Ruprecht K, Havla J, Krumbholz M, Kümpfel T, Aktas O, Hartung HP, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Stellmann JP, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Zeltner L, Ziemann U, Linker R, Schwab M, Marziniak M, Bergh FT, Hofstadt-van Oy U, Neuhaus O, Winkelmann A, Marouf W, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C; NEMOS (Neuromyelitis Optica Study Group) (2015). Neuromyelitis optica: Evaluation of 871 attacks and 1153 treatment courses. Ann Neurol. 2015 Nov 4. doi: 10.1002/ana.24554. [Epub ahead of print]
Knier B, Berthele A, Buck D, Schmidt P, Zimmer C, Mühlau M, Hemmer B, Korn T (2015). Optical coherence tomography indicates disease activity prior to clinical onset of central nervous system demyelination. Mult Scler. 2015 Sep 11. pii: 1352458515604496. [Epub ahead of print]
Kolber P, Luessi F, Meuth SG, Klotz L, Korn T, Trebst C, Tackenberg B, Kieseier B, Kümpfel T, Fleischer V, Tumani H, Wildemann B, Lang M, Flachenecker P, Meier U, Brück W, Limmroth V, Haghikia A, Hartung HP, Stangel M, Hohlfeld R, Hemmer B, Gold R, Wiendl H, Zipp F (2015). Current aspects of therapy conversion for multiple sclerosis [Article in German] Nervenarzt. 2015 Aug 13. [Epub ahead of print]
Kovacs KT, Kalluri SR, Boza-Serrano A, Deierborg T, Csepany T, Simo M, Rokusz L, Miseta A, Alcaraz N, Czirjak L, Berki T, Molnar T, Hemmer B, Illes Z (2015). Change in autoantibody and cytokine responses during the evolution of neuromyelitis optica in patients with systemic lupus erythematosus: A preliminary study. Mult Scler. 2015 Oct 29. pii: 1352458515613165. [Epub ahead of print]
Kowarik MC, Dzieciatkowska M, Wemlinger S, Ritchie AM, Hemmer B, Owens GP, Bennett JL (2015). The cerebrospinal fluid immunoglobulin transcriptome and proteome in neuromyelitis optica reveals central nervous system-specific B cell populations. J Neuroinflammation. 2015 Jan 28;12(1):19. [Epub ahead of print]
Schirmer L, Wölfel S, Georgi E, Ploner M, Bauer B, Hemmer B (2015). Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis. Open Forum Infect Dis. 2015 Sep 1;2(3):ofv124. doi: 10.1093/ofid/ofv124. eCollection 2015.

Biberacher V, Boucard CC, Schmidt P, Engl C, Buck D, Berthele A, Hoshi MM, Zimmer C, Hemmer B, Mühlau M (2014). Atrophy and structural variability of the upper cervical cord in early multiple sclerosis. Mult Scler. 2014 Aug 19. pii: 1352458514546514. [Epub ahead of print]
Buck D, Hemmer B (2014). Biomarkers of treatment response in multiple sclerosis. Expert Rev Neurother. 2014 Feb;14(2):165-72. doi: 10.1586/14737175.2014.874289. Epub 2014 Jan 6.
Geis C, Ritter C, Ruschil C, Weishaupt A, Grünewald B, Stoll G, Holmoy T, Misu T, Fujihara K, Hemmer B, Stadelmann C, Bennett JL, Sommer C, Toyka KV (2014). The intrinsic pathogenic role of autoantibodies to aquaporin 4 mediating spinal cord disease in a rat passive-transfer model. Exp Neurol. 2014 Dec 24. pii: S0014-4886(14)00400-2. doi: 10.1016/j.expneurol.2014.12.015. [Epub ahead of print]
Gnanapavan S, Hegen H, Khalil M, Hemmer B, Franciotta D, Hughes S, Hintzen R, Jeromin A, Havrdova E, Tumani H, Bertolotto A, Comabella M, Frederiksen J, Alvarez-Cermeño JC, Villar L, Galimberti D, Myhr KM, Dujmovic I, Fazekas F, Ionete C, Menge T, Keir G, Deisenhammer F, Teunissen C, Giovannoni G (2014). Guidelines for uniform reporting of body fluid biomarker studies in neurologic disorders. Neurology. 2014 Aug 22. pii: 10.1212/WNL.0000000000000809. [Epub ahead of print]
Heinemann C, Heink S, Petermann F, Vasanthakumar A, Rothhammer V, Doorduijn E, Mitsdoerffer M, Sie C, Prazeres da Costa O, Buch T, Hemmer B, Oukka M, Kallies A, Korn T (2014). IL-27 and IL-12 oppose pro-inflammatory IL-23 in CD4(+) T cells by inducing Blimp1. Nat Commun. 2014 May 6;5:3770. doi: 10.1038/ncomms4770.
Hemmer B, Calabresi PA (2014). Complex antibody profiling to predict clinical outcome in childhood ADS. Neurology. 2014 Nov 7. pii: 10.1212/WNL.0000000000001083. [Epub ahead of print]
Knier B, Rothhammer V, Heink S, Puk O, Graw J, Hemmer B, Korn T (2014). Neutralizing IL-17 protects the optic nerve from autoimmune pathology and prevents retinal nerve fiber layer atrophy during experimental autoimmune encephalomyelitis. J Autoimmun. 2014 Oct 1. pii: S0896-8411(14)00132-2. doi: 10.1016/j.jaut.2014.09.003. [Epub ahead of print]
Knier B, Hemmer B, Korn T (2014). Novel monoclonal antibodies for therapy of multiple sclerosis. Expert Opin Biol Ther. 2014 Feb 28. [Epub ahead of print]
Kraus V, Srivastava R, Kalluri SR, Seidel U, Schuelke M, Schimmel M, Rostasy K, Leiz S, Hosie S, Grummel V, Hemmer B (2014). Potassium channel KIR4.1-specific antibodies in children with acquired demyelinating CNS disease. Neurology. 2014 Jan 10. [Epub ahead of print]
Mühlau M, Engl C, Boucard CC, Schmidt P, Biberacher V, Görsch I, Sorg C, Wohlschläger A, Zimmer C, Hemmer B, Weindl A (2014). Spinal cord atrophy in early Huntington's disease. Ann Clin Transl Neurol. 2014 Apr;1(4):302-6. doi: 10.1002/acn3.52. Epub 2014 Mar 24
Rothhammer V, Muschaweckh A, Gasteiger G, Petermann F, Heink S, Busch DH, Heikenwälder M, Hemmer B, Drexler I, Korn T (2014). α4-integrins control viral meningoencephalitis through differential recruitment of T helper cell subsets. Acta Neuropathol Commun. 2014 Mar 7;2(1):27. doi: 10.1186/2051-5960-2-27.
Schirmer L, Srivastava R, Hemmer B (2014). To look for a needle in a haystack: the search for autoantibodies in multiple sclerosis. Mult Scler. 2014 Mar;20(3):271-9. doi: 10.1177/1352458514522104.
Schirmer L, Srivastava R, Kalluri SR, Böttinger S, Herwerth M, Carassiti D, Srivastava B, Gempt J, Schlegel J, Kuhlmann T, Korn T, Reynolds R, Hemmer B (2014). Differential loss of KIR4.1 immunoreactivity in multiple sclerosis lesions. Ann Neurol. 2014 Apr 29. doi: 10.1002/ana.24168. [Epub ahead of print]
Stüve O, Hemmer B (2014). The genetics of natalizumab hypersensitivity: One learns to itch where one can scratch. Neurol Neuroimmunol Neuroinflamm. 2014 Dec 11;1(4):e52. doi: 10.1212/NXI.0000000000000052. eCollection 2014.
Sundqvist E, Buck D, Warnke C, Albrecht E, Gieger C, Khademi M, Lima Bomfim I, Fogdell-Hahn A, Link J, Alfredsson L, Søndergaard HB, Hillert J; International Multiple Sclerosis Genetics Consortium, Oturai AB, Hemmer B, Kockum I, Olsson T (2014). JC polyomavirus infection is strongly controlled by human leucocyte antigen class II variants. PLoS Pathog. 2014 Apr 24;10(4):e1004084. doi: 10.1371/journal.ppat.1004084. eCollection 2014

Buck D, Albrecht E, Aslam M, Goris A, Hauenstein N, Jochim A; International Multiple Sclerosis Genetics Consortium, Wellcome Trust Case Control Consortium, Cepok S, Grummel V, Dubois B, Berthele A, Lichtner P, Gieger C, Winkelmann J, Hemmer B (2013). Genetic variants in the immunoglobulin heavy chain locus are associated with the IgG index in multiple sclerosis. Ann Neurol. 73(1):86-94 (2013)
Hemmer B, Srivastava R (2013). Hunting for autoantibodies in multiple sclerosis. Neurology. 2013 Aug 6. [Epub ahead of print]
Selter RC, Hemmer B. Update on immunopathogenesis and immunotherapy in multiple sclerosis. Immunotargets Ther. 2013 Apr 25;2:21-30. doi: 10.2147/ITT.S31813. PMID: 27471685; PMCID: PMC4928362.

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Hemmer, Bernhard

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