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                                                          4. Franzmeier, Nicolai

                                                          Franzmeier, Nicolai

                                                          2025

                                                          • Bauer T, Brendel M, Zaganjori M, Bernhardt AM, Jäck A, Stöcklein S, Scheifele M, Levin J, van Eimeren T, Drzezga A, Sabri O, Barthel H, Perneczky R, Höglinger G, Franzmeier N, Gnörich J; German Imaging Initiative for Tauopathies (GII4T). Pragmatic algorithm for visual assessment of 4-Repeat tauopathies in [18F]PI-2620 PET Scans. Neuroimage. 2025 Jan 9;306:121001. doi: 10.1016/j.neuroimage.2025.121001. Epub ahead of print. PMID: 39798829.
                                                          • Biel D, Suárez-Calvet M, Dewenter A, Steward A, Roemer SN, Dehsarvi A, Zhu Z, Pescoller J, Frontzkowski L, Kreuzer A, Haass C, Schöll M, Brendel M, Franzmeier N. Female sex is linked to a stronger association between sTREM2 and CSF p-tau in Alzheimer's disease. EMBO Mol Med. 2025 Jan 10. doi: 10.1038/s44321-024-00190-3. Epub ahead of print. PMID: 39794447. 
                                                          • de Bruin H, Groot C, Kamps S, Vijverberg EGB, Steward A, Dehsarvi A, Pijnenburg YAL, Ossenkoppele R, Franzmeier N. Amyloid-β and tau deposition in traumatic brain injury: a study of Vietnam War veterans. Brain Commun. 2025 Jan 10;7(1):fcaf009. doi: 10.1093/braincomms/fcaf009. PMID: 39845735; PMCID: PMC11752645.
                                                          • Leuzy A, Bollack A, Pellegrino D, Teunissen CE, La Joie R, Rabinovici GD, Franzmeier N, Johnson K, Barkhof F, Shaw LM, Arkhipenko A, Schindler SE, Honig LS, Moscoso Rial A, Schöll M, Zetterberg H, Blennow K, Hansson O, Farrar G. Considerations in the clinical use of amyloid PET and CSF biomarkers for Alzheimer's disease. Alzheimers Dement. 2025 Mar;21(3):e14528. doi: 10.1002/alz.14528. PMID: 40042435; PMCID: PMC11881640.

                                                          • Quattrone A, Franzmeier N, Levin J, Petzold GC, Spottke A, Brosseron F, Falkenburger B, Prudlo J, Gasser T; DESCRIBE‐PSP Group, The ProPSP Group; Höglinger GU. Prospective Multicenter Evaluation of the MDS "Suggestive of PSP" Diagnostic Criteria. Mov Disord. 2025 Jan 10. doi: 10.1002/mds.30112. Epub ahead of print. PMID: 39797511.
                                                          • Roemer-Cassiano SN, Wagner F, Evangelista L, Rauchmann BS, Dehsarvi A, Steward A, Dewenter A, Biel D, Zhu Z, Pescoller J, Gross M, Perneczky R, Malpetti M, Ewers M, Schöll M, Dichgans M, Höglinger GU, Brendel M, Jäkel S, Franzmeier N. Amyloid-associated hyperconnectivity drives tau spread across connected brain regions in Alzheimer's disease. Sci Transl Med. 2025 Jan 22;17(782):eadp2564. doi: 10.1126/scitranslmed.adp2564. Epub 2025 Jan 22. PMID: 39841807.
                                                          • Scheifele M, Gnörich J, Schröder E, Kunte SC, Ells Z, Hagen J, Katzdobler S, Palleis C, Bernhardt A, Jäck A, Franzmeier N, Fischer M, Levin J, Höglinger GU, Werner RA, Brendel M. Feasibility of a single-day protocol for SPECT and PET assessment of dopamine transporter availability, cardiac innervation and metabolic patterns in patients with movement disorders. Eur J Nucl Med Mol Imaging. 2025 Mar 11. doi: 10.1007/s00259-025-07188-0. Epub ahead of print. PMID: 40064709.
                                                          • Völter F, Eckenweber S, Scheifele M, Eckenweber F, Hirsch F, Franzmeier N, Kreuzer A, Griessl M, Steward A, Janowitz D, Palleis C, Bernhardt A, Vöglein J, Stockbauer A, Rauchmann BS, Schöberl F, Wlasich E, Buerger K, Wagemann O, Perneczky R, Weidinger E, Höglinger G, Levin J, Brendel M, Schönecker S. Correlation of early-phase β-amyloid positron-emission-tomography and neuropsychological testing in patients with Alzheimer's disease. Eur J Nucl Med Mol Imaging. 2025 Feb 28. doi: 10.1007/s00259-025-07175-5. Epub ahead of print. PMID: 40019578.
                                                          • Wagemann O, Brendel M, Franzmeier N, Nübling G, Gnörich J, Zaganjori M, Prix C, Stockbauer A, Wlasich E, Loosli SV, Sandkühler K, Frontzkowski L, Höglinger G, Levin J. Feasibility and potential diagnostic value of [18F]PI-2620 PET in patients with down syndrome and Alzheimer's disease: a case series. Front Neurosci. 2025 Jan 6;18:1505999. doi: 10.3389/fnins.2024.1505999. PMID: 39834700; PMCID: PMC11744071.

                                                          2024
                                                          • Biechele G, Rauchmann BS, Janowitz D, Buerger K, Franzmeier N, Weidinger E, Guersel S, Schuster S, Finze A, Harris S, Lindner S, Albert NL, Wetzel C, Rupprecht R, Rominger A, Palleis C, Katzdobler S, Burow L, Kurz C, Zaganjori M, Trappmann LK, Goldhardt O, Grimmer T, Haeckert J, Keeser D, Stoecklein S, Morenas-Rodriguez E, Bartenstein P, Levin J, Höglinger GU, Simons M, Perneczky R, Brendel M. Associations between sex, body mass index and the individual microglial response in Alzheimer's disease. J Neuroinflammation. 2024 Jan 23;21(1):30. doi:10.1186/s12974-024-03020-y. PMID: 38263017; PMCID: PMC10804830.
                                                          • Brendel M, Parvizi T, Gnörich J, Topfstedt CE, Buerger K, Janowitz D, Rauchmann BS, Perneczky R, Kurz C, Mehrens D, Kunz WG, Kusche-Palenga J, Kling AB, Buchal A, Nestorova E, Silvaieh S, Wurm R, Traub-Weidinger T, Klotz S, Regelsberger G, Rominger A, Drzezga A, Levin J, Stögmann E, Franzmeier N, Höglinger GU. Aβ status assessment in a hypothetical scenario prior to treatment with disease-modifying therapies: Evidence from 10-year real-world experience at university memory clinics. Alzheimers Dement (Amst). 2024 Nov 22;16(4):e70031. doi: 10.1002/dad2.70031. PMID: 39583651; PMCID: PMC11582924.
                                                          • Dilcher R, Wall S, Groß M, Katzdobler S, Wagemann O, Palleis C, Weidinger E, Fietzek U, Bernhardt A, Kurz C, Ferschmann C, Scheifele M, Zaganjori M, Gnörich J, Bürger K, Janowitz D, Rauchmann BS, Stöcklein S, Bartenstein P, Villemagne V, Seibyl J, Sabri O, Barthel H, Perneczky R, Schöberl F, Zwergal A, Höglinger GU, Levin J, Franzmeier N, Brendel M. Combining cerebrospinal fluid and PI-2620 tau-PET for biomarker-based stratification of Alzheimer's disease and 4R-tauopathies. Alzheimers Dement. 2024 Sep 12. doi: 10.1002/alz.14185. Epub ahead of print. PMID: 39263969.
                                                          • Dinkel L, Hummel S, Zenatti V, Malara M, Tillmann Y, Colombo A, Monasor LS, Suh JH, Logan T, Roth S, Paeger L, Hoffelner P, Bludau O, Schmidt A, Müller SA, Schifferer M, Nuscher B, Njavro JR, Prestel M, Bartos LM, Wind-Mark K, Slemann L, Hoermann L, Kunte ST, Gnörich J, Lindner S, Simons M, Herms J, Paquet D, Lichtenthaler SF, Bartenstein P, Franzmeier N, Liesz A, Grosche A, Bremova-Ertl T, Catarino C, Beblo S, Bergner C, Schneider SA, Strupp M, Di Paolo G, Brendel M, Tahirovic S. Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease. Sci Transl Med. 2024 Dec 4;16(776):eadl4616. doi: 10.1126/scitranslmed.adl4616. Epub 2024 Dec 4. PMID: 39630885.
                                                          • Ferschmann C, Messerschmidt K, Gnörich J, Barthel H, Marek K, Palleis C, Katzdobler S, Stockbauer A, Fietzek U, Finze A, Biechele G, Rumpf JJ, Saur D, Schroeter ML, Rullmann M, Beyer L, Eckenweber F, Wall S, Schildan A, Patt M, Stephens A, Classen J, Bartenstein P, Seibyl J, Franzmeier N, Levin J, Höglinger GU, Sabri O, Brendel M, Scheifele M; German Imaging Initiative for Tauopathies (GII4T). Tau accumulation is associated with dopamine deficiency in vivo in four-repeat tauopathies. Eur J Nucl Med Mol Imaging. 2024 Feb 17. doi: 10.1007/s00259-024-06637-6. Epub ahead of print. PMID: 38366196.
                                                          • Franzmeier N, Dehsarvi A, Steward A, Biel D, Dewenter A, Roemer SN, Wagner F, Groß M, Brendel M, Moscoso A, Arunachalam P, Blennow K, Zetterberg H, Ewers M, Schöll M. Elevated CSF GAP-43 is associated with accelerated tau accumulation and spread in Alzheimer's disease. Nat Commun. 2024 Jan 3;15(1):202. doi: 10.1038/s41467-023-44374-w. PMID: 38172114; PMCID: PMC10764818.
                                                          • Gnörich J, Koehler M, Wind-Mark K, Klaus C, Zatcepin A, Palumbo G, Lalia M, Monasor LS, Beyer L, Eckenweber F, Scheifele M, Gildehaus FJ, von Ungern-Sternberg B, Barthel H, Sabri O, Bartenstein P, Herms J, Tahirovic S, Franzmeier N, Ziegler S, Brendel M. Towards multicenter β-amyloid PET imaging in mouse models: A triple scanner head-to-head comparison. Neuroimage. 2024 Jul 26;297:120748. doi: 10.1016/j.neuroimage.2024.120748. Epub ahead of print. PMID: 39069223.
                                                          • Luan Y, Rubinski A, Biel D, Otero Svaldi D, Alonzo Higgins I, Shcherbinin S, Pontecorvo M, Franzmeier N, Ewers M; Alzheimer’s Disease Neuroimaging Initiative ADNI. Tau-network mapping of domain-specific cognitive impairment in Alzheimer's disease. Neuroimage Clin. 2024 Oct 30;44:103699. doi: 10.1016/j.nicl.2024.103699. Epub ahead of print. PMID: 39509992.
                                                          • Malpetti M, Franzmeier N, Brendel M. PET Imaging to Measure Neuroinflammation In Vivo. Methods Mol Biol. 2024;2785:177-193. doi: 10.1007/978-1-0716-3774-6_12. PMID: 38427195.
                                                          • Malpetti M, Roemer SN, Harris S, Gross M, Gnörich J, Stephens A, Dewenter A, Steward A, Biel D, Dehsarvi A, Wagner F, Müller A, Koglin N, Weidinger E, Palleis C, Katzdobler S, Rupprecht R, Perneczky R, Rauchmann BS, Levin J, Höglinger GU, Brendel M, Franzmeier N. Neuroinflammation Parallels 18F-PI-2620 Positron Emission Tomography Patterns in Primary 4-Repeat Tauopathies. Mov Disord. 2024 Jul 18. doi: 10.1002/mds.29924. Epub ahead of print. PMID: 39022835.

                                                          • Meindl M, Zatcepin A, Gnörich J, Scheifele M, Zaganjori M, Groß M, Lindner S, Schaefer R, Simmet M, Roemer S, Katzdobler S, Levin J, Höglinger G, Bischof AC, Barthel H, Sabri O, Bartenstein P, Saller T, Franzmeier N, Ziegler S, Brendel M. Assessment of [18F]PI-2620 Tau-PET Quantification via Non-Invasive Automatized Image Derived Input Function. Eur J Nucl Med Mol Imaging. 2024 May 8. doi: 10.1007/s00259-024-06741-7. Epub ahead of print. PMID: 38717592.

                                                          • Palleis C, Franzmeier N, Weidinger E, Bernhardt AM, Katzdobler S, Wall S, Ferschmann C, Harris S, Schmitt J, Schuster S, Gnörich J, Finze A, Biechele G, Lindner S, Albert NL, Bartenstein P, Sabri O, Barthel H, Rupprecht R, Nuscher B, Stephens AW, Rauchmann BS, Perneczky R, Haass C, Brendel M, Levin J, Höglinger GU. Association of Neurofilament Light Chain, [18F]PI-2620 Tau-PET, TSPO-PET, and Clinical Progression in Patients With β-Amyloid-Negative CBS. Neurology. 2024 Jan 9;102(1):e207901. doi: 10.1212/WNL.0000000000207901. Epub 2023 Dec 14. PMID: 38165362.
                                                          • Perellón-Alfonso R, Abellaneda-Pérez K, Pileckyte I, Cabello-Toscano M, Mulet-Pons L, Vaqué-Alcázar L, Cattaneo G, Redondo-Camós M, España-Irla G, Delgado-Gallen S, Sánchez JS, Zetterberg H, Tormos JM, Franzmeier N, Pascual-Leone A, Bartrés-Faz D. Spontaneous and perturbation-based EEG cortical excitability markers are associated with plasma p-tau181 concentration in healthy middle-aged adults. Heliyon. 2024 Dec 10;10(24):e41118. doi: 10.1016/j.heliyon.2024.e41118. PMID: 39759333; PMCID: PMC11700258.
                                                          • Quattrone A, Franzmeier N, Huppertz HJ, Klietz M, Roemer SN, Boxer AL, Levin J, Höglinger GU; AL‐108‐231 Investigators, the Tauros MRI Investigators, the PASSPORT Study Group, the DESCRIBE‐PSP Group. Magnetic Resonance Imaging Measures to Track Atrophy Progression in Progressive Supranuclear Palsy in Clinical Trials. Mov Disord. 2024 Jun 2. doi: 10.1002/mds.29866. Epub ahead of print. PMID: 38825840.
                                                          • Roemer SN, Brendel M, Gnoerich J, Malpetti M, Zaganjori M, Quattrone A, Gross M, Steward A, Dewenter A, Wagner F, Dehsarvi A, Ferschmann C, Wall S, Palleis C, Rauchmann BS, Katzdobler S, Jaeck A, Stockbauer A, Fietzek UM, Bernhardt AM, Weidinger E, Zwergal A, Stoecklein S, Perneczky R, Barthel H, Sabri O, Levin J, Hoeglinger GU, Franzmeier N. Subcortical tau is linked to hypoperfusion in connected cortical regions in 4-repeat tauopathies. Brain. 2024 Jun 6:awae174. doi: 10.1093/brain/awae174. Epub ahead of print. PMID: 38842726.
                                                          • Schönecker S, Martinez-Murcia FJ, Denecke J, Franzmeier N, Danek A, Wagemann O, Prix C, Wlasich E, Vöglein J, Loosli SV, Brauer A, Górriz Sáez JM, Bouzigues A, Russell LL, Foster PH, Ferry-Bolder E, van Swieten JC, Jiskoot LC, Seelaar H, Sanchez-Valle R, Laforce R Jr, Graff C, Galimberti D, Vandenberghe R, de Mendonça A, Tiraboschi P, Santana I, Gerhard A, Sorbi S, Otto M, Pasquier F, Ducharme S, Butler C, Le Ber I, Finger E, Tartaglia MC, Masellis M, Rowe JB, Synofzik M, Moreno F, Borroni B, Rohrer JD; Genetic Frontotemporal Dementia Initiative (GENFI); Priller J, Höglinger GU, Levin J. Frequency and Longitudinal Course of Behavioral and Neuropsychiatric Symptoms in Participants With Genetic Frontotemporal Dementia. Neurology. 2024 Oct 22;103(8):e209569. doi: 10.1212/WNL.0000000000209569. Epub 2024 Sep 16. PMID: 39284109; PMCID: PMC11399068.
                                                          • Slemann L, Gnörich J, Hummel S, Bartos LM, Klaus C, Kling A, Kusche-Palenga J, Kunte ST, Kunze LH, Englert AL, Li Y, Vogler L, Katzdobler S, Palleis C, Bernhardt A, Jäck A, Zwergal A, Hopfner F, Roemer-Cassiano SN, Biechele G, Stöcklein S, Bischof G, van Eimeren T, Drzezga A, Sabri O, Barthel H, Respondek G, Grimmer T, Levin J, Herms J, Paeger L, Willroider M, Beyer L, Höglinger GU, Roeber S, Franzmeier N, Brendel M. Neuronal and oligodendroglial, but not astroglial, tau translates to in vivo tau PET signals in individuals with primary tauopathies. Acta Neuropathol. 2024 Nov 24;148(1):70. doi: 10.1007/s00401-024-02834-7. PMID: 39580770; PMCID: PMC11586312.
                                                          • Zatcepin A, Gnörich J, Rauchmann BS, Bartos LM, Wagner S, Franzmeier N, Malpetti M, Xiang X, Shi Y, Parhizkar S, Grosch M, Wind-Mark K, Kunte ST, Beyer L, Meyer C, Brösamle D, Wendeln AC, Osei-Sarpong C, Heindl S, Liesz A, Stoecklein S, Biechele G, Finze A, Eckenweber F, Lindner S, Rominger A, Bartenstein P, Willem M, Tahirovic S, Herms J, Buerger K, Simons M, Haass C, Rupprecht R, Riemenschneider MJ, Albert NL, Beyer M, Neher JJ, Paeger L, Levin J, Höglinger GU, Perneczky R, Ziegler SI, Brendel M. Regional desynchronization of microglial activity is associated with cognitive decline in Alzheimer's disease. Mol Neurodegener. 2024 Sep 5;19(1):64. doi: 10.1186/s13024-024-00752-6. PMID: 39238030; PMCID: PMC11375924.

                                                          2023

                                                          • Biel D, Suárez-Calvet M, Hager P, Rubinski A, Dewenter A, Steward A, Roemer S, Ewers M, Haass C, Brendel M, Franzmeier N; Alzheimer's Disease Neuroimaging Initiative (ADNI) (2023). sTREM2 is associated with amyloid-related p-tau increases and glucose hypermetabolism in Alzheimer's disease. EMBO Mol Med. 2023 Jan 9:e16987. doi: 10.15252/emmm.202216987. Epub ahead of print. PMID: 36620941.
                                                          • Coenen M, Biessels GJ, DeCarli C, Fletcher EF, Maillard PM; Alzheimer's Disease Neuroimaging Initiative; Barkhof F, Barnes J, Benke T, Boomsma JMF, P L H Chen C, Dal-Bianco P, Dewenter A, Duering M, Enzinger C, Ewers M, Exalto LG, Franzmeier N, Groeneveld O, Hilal S, Hofer E, Koek HL, Maier AB, McCreary CR, Papma JM, Paterson RW, Pijnenburg YAL, Rubinski A, Schmidt R, Schott JM, Slattery CF, Smith EE, Sudre CH, Steketee RME, van den Berg E, van der Flier WM, Venketasubramanian N, Vernooij MW, Wolters FJ, Xin X, Biesbroek JM, Kuijf HJ. Spatial distributions of white matter hyperintensities on brain MRI: A pooled analysis of individual participant data from 11 memory clinic cohorts. Neuroimage Clin. 2023;40:103547. doi: 10.1016/j.nicl.2023.103547. Epub 2023 Nov 23. PMID: 38035457; PMCID: PMC10698002.
                                                          • Finze A, Biechele G, Rauchmann BS, Franzmeier N, Palleis C, Katzdobler S, Weidinger E, Guersel S, Schuster S, Harris S, Schmitt J, Beyer L, Gnörich J, Lindner S, Albert NL, Wetzel CH, Rupprecht R, Rominger A, Danek A, Burow L, Kurz C, Tato M, Utecht J, Papazov B, Zaganjori M, Trappmann LK, Goldhardt O, Grimmer T, Haeckert J, Janowitz D, Buerger K, Keeser D, Stoecklein S, Dietrich O, Morenas-Rodriguez E, Barthel H, Sabri O, Bartenstein P, Simons M, Haass C, Höglinger GU, Levin J, Perneczky R, Brendel M (2023). Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies. Mol Psychiatry. 2023 Jul 26. doi: 10.1038/s41380-023-02188-8. Epub ahead of print. PMID: 37495886.
                                                          • Levin F, Grothe MJ, Dyrba M, Franzmeier N, Teipel SJ; Alzheimer’s Disease Neuroimaging Initiative. Longitudinal trajectories of cognitive reserve in hypometabolic subtypes of Alzheimer's disease. Neurobiol Aging. 2023 Dec 19;135:26-38. doi: 10.1016/j.neurobiolaging.2023.12.003. Epub ahead of print. PMID: 38157587.
                                                          • Kolabas ZI, Kuemmerle LB, Perneczky R, Förstera B, Ulukaya S, Ali M, Kapoor S, Bartos LM, Büttner M, Caliskan OS, Rong Z, Mai H, Höher L, Jeridi D, Molbay M, Khalin I, Deligiannis IK, Negwer M, Roberts K, Simats A, Carofiglio O, Todorov MI, Horvath I, Ozturk F, Hummel S, Biechele G, Zatcepin A, Unterrainer M, Gnörich J, Roodselaar J, Shrouder J, Khosravani P, Tast B, Richter L, Díaz-Marugán L, Kaltenecker D, Lux L, Chen Y, Zhao S, Rauchmann BS, Sterr M, Kunze I, Stanic K, Kan VWY, Besson-Girard S, Katzdobler S, Palleis C, Schädler J, Paetzold JC, Liebscher S, Hauser AE, Gokce O, Lickert H, Steinke H, Benakis C, Braun C, Martinez-Jimenez CP, Buerger K, Albert NL, Höglinger G, Levin J, Haass C, Kopczak A, Dichgans M, Havla J, Kümpfel T, Kerschensteiner M, Schifferer M, Simons M, Liesz A, Krahmer N, Bayraktar OA, Franzmeier N, Plesnila N, Erener S, Puelles VG, Delbridge C, Bhatia HS, Hellal F, Elsner M, Bechmann I, Ondruschka B, Brendel M, Theis FJ, Erturk A (2023). Distinct molecular profiles of skull bone marrow in health and neurological disorders. Cell. 2023 Aug 3:S0092-8674(23)00742-0. doi: 10.1016/j.cell.2023.07.009. Epub ahead of print. PMID: 37562402
                                                          • Vogel JW, Corriveau-Lecavalier N, Franzmeier N, Pereira JB, Brown JA,. Maass A, Botha H, Seeley WW, Bassett DS, Jones DT, Ewers M (2023). Connectome-based modelling of neurodegenerative diseases: towards. precision medicine and mechanistic insight. Nat Rev Neurosci. 2023 Aug. 24. doi: 10.1038/s41583-023-00731-8. Epub ahead of print. PMID: 37620599.

                                                          2022

                                                          • Biel D, Luan Y, Brendel M, Hager P, Dewenter A, Moscoso A, Otero Svaldi D, Higgins IA, Pontecorvo M, Römer S, Steward A, Rubinski A, Zheng L, Schöll M, Shcherbinin S, Ewers M, Franzmeier N; Alzheimer’s Disease Neuroimaging Initiative (2022). Combining tau-PET and fMRI meta-analyses for patient-centered prediction of cognitive decline in Alzheimer's disease. Alzheimers Res Ther. 2022 Nov 7;14(1):166. doi: 10.1186/s13195-022-01105-5. PMID: 36345046; PMCID: PMC9639286.
                                                          • Blume T, Deussing M, Biechele G, Peters F, Zott B, Schmidt C, Franzmeier N, Wind K, Eckenweber F, Sacher C, Shi Y, Ochs K, Kleinberger G, Xiang X, Focke C, Lindner S, Gildehaus FJ, Beyer L, von Ungern-Sternberg B, Bartenstein P, Baumann K, Adelsberger H, Rominger A, Cumming P, Willem M, Dorostkar MM, Herms J, Brendel M (2022). Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition. Front Aging Neurosci. 2022 Mar 30;14:854031. doi: 10.3389/fnagi.2022.854031. PMID: 35431893; PMCID: PMC9007038.
                                                          • Dewenter A, Jacob MA, Cai M, Gesierich B, Hager P, Kopczak A, Biel D, Ewers M, Tuladhar AM, de Leeuw FE, Dichgans M, Franzmeier N. Duering M; SVDs@target Consortium and Alzheimer’s Disease Neuroimaging Initiative (ADNI) (2022). Disentangling the effects of Alzheimer's and small vessel disease on white matter fibre tracts. Brain. 2022 Jul 21:awac265. doi: 10.1093/brain/awac265. Epub ahead of print. PMID: 35859352.
                                                          • Franzmeier N, Brendel M, Beyer L, Slemann L, Kovacs GG, Arzberger T, Kurz C, Respondek G, Lukic MJ, Biel D, Rubinski A, Frontzkowski L, Hummel S, Müller A, Finze A, Palleis C, Joseph E, Weidinger E, Katzdobler S, Song M, Biechele G, Kern M, Scheifele M, Rauchmann BS, Perneczky R, Rullman M, Patt M, Schildan A, Barthel H, Sabri O, Rumpf JJ, Schroeter ML, Classen J, Villemagne V, Seibyl J, Stephens AW, Lee EB, Coughlin DG, Giese A, Grossman M, McMillan CT, Gelpi E, Molina-Porcel L, Compta Y, van Swieten JC, Laat LD, Troakes C, Al-Sarraj S, Robinson JL, Xie SX, Irwin DJ, Roeber S, Herms J, Simons M, Bartenstein P, Lee VM, Trojanowski JQ, Levin J, Höglinger G, Ewers M (2022). Tau deposition patterns are associated with functional connectivity in primary tauopathies. Nat Commun. 2022 Mar 15;13(1):1362. doi: 10.1038/s41467-022-28896-3. PMID: 35292638; PMCID: PMC8924216
                                                          • Frontzkowski L, Ewers M, Brendel M, Biel D, Ossenkoppele R, Hager P, Steward A, Dewenter A, Römer S, Rubinski A, Buerger K, Janowitz D, Binette AP, Smith R, Strandberg O, Carlgren NM, Dichgans M, Hansson O, Franzmeier N (2022). Earlier Alzheimer's disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading. Nat Commun. 2022 Aug 20;13(1):4899. doi: 10.1038/s41467-022-32592-7. PMID: 35987901; PMCID: PMC9392750.
                                                          • 125. Katzdobler S, Nitschmann A, Barthel H, Bischof G, Beyer L, Marek K, Song M, Wagemann O, Palleis C, Weidinger E, Nack A, Fietzek U, Kurz C, Strupp M,Häckert J, Stapf T, Ferschmann C, Scheifele M, Eckenweber F, Biechele G, Franzmeier N, Dewenter A, Schönecker S, Saur D, Schroeter ML, Rumpf JJ, Rullmann M, Schildan A, Patt M, Stephens AW, van Eimeren T, Neumaier B, Drzezga A, Danek A, Classen J, Bürger K, Janowitz D, Rauchmann BS, Stöcklein S, Perneczky R, Schöberl F, Zwergal A, Höglinger GU, Bartenstein P, Villemagne V, Seibyl J, Sabri O, Levin J, Brendel M; German Imaging Initiative for Tauopathies (GII4T) (2022). Additive value of [18F]PI-2620 perfusion imaging in progressive supranuclear palsy and corticobasal syndrome. Eur J Nucl Med Mol Imaging. 2022 Sep 14. doi: 10.1007/s00259-022-05964-w. Epub ahead of print. PMID: 36102964.
                                                          • Morenas-Rodríguez E, Li Y, Nuscher B, Franzmeier N, Xiong C, Suárez-Calvet M, Fagan AM, Schultz S, Gordon BA, Benzinger TLS, Hassenstab J, McDade E, Feederle R, Karch CM, Schlepckow K, Morris JC, Kleinberger G, Nellgard B, Vöglein J, Blennow K, Zetterberg H, Ewers M, Jucker M, Levin J, Bateman RJ, Haass C; Dominantly Inherited Alzheimer Network (2022). Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study. Lancet Neurol. 2022 Apr;21(4):329-341. doi: 10.1016/S1474-4422(22)00027-8. PMID: 35305339; PMCID: PMC8926925.
                                                          • Pichet Binette A, Franzmeier N, Spotorno N, Ewers M, Brendel M, Biel D; Alzheimer’s Disease Neuroimaging Initiative; Strandberg O, Janelidze S, Palmqvist S, Mattsson-Carlgren N, Smith R, Stomrud E, Ossenkoppele R, Hansson O. Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer's disease. Nat Commun. 2022 Nov 4;13(1):6635. doi: 10.1038/s41467-022-34129-4. PMID: 36333294; PMCID: PMC9636262.
                                                          • Rauchmann BS, Brendel M, Franzmeier N, Trappmann L, Ewers M, Palleis C, Weidinger E, Biechele G, Schuster S, Finze A, Eckenweber F, Rupprecht R, Rominger A, Goldhardt O, Grimmer T, Keeser D, Stoecklein S, Dietrich O, Bartenstein P, Levin J, Höglinger G, Perneczky R (2022). Microglial Activation and Connectivity in Alzheimer Disease and Aging. Ann Neurol. 2022 Aug 1. doi: 10.1002/ana.26465. Epub ahead of print. PMID: 36053756.
                                                          • Rubinski A, Franzmeier N, Dewenter A, Luan Y, Smith R, Strandberg O, Ossenkoppele R, Dichgans M, Hansson O, Ewers M; Alzheimer’s Disease Neuroimaging Initiative (ADNI) (2022). Higher levels of myelin are associated with higher resistance against tau pathology in Alzheimer's disease. Alzheimers Res Ther. 2022 Sep 24;14(1):139. doi: 10.1186/s13195-022-01074-9. PMID: 36153607; PMCID: PMC9508747.
                                                          • Rubinski A, Frerich S, Malik R, Franzmeier N, Ramirez A, Dichgans M, Ewers M; Alzheimer's Disease Neuroimaging Initiative (ADNI) (2022). Polygenic effect on tau pathology progression in Alzheimer's disease. Ann Neurol. 2022 Dec 26. doi: 10.1002/ana.26588. Epub ahead of print. PMID: 36571564.
                                                          • Schönecker S, Martinez-Murcia FJ, Rauchmann BS, Franzmeier N, Prix C, Wlasich E, Loosli SV, Bochmann K, Gorriz Saez JM, Laforce R Jr, Ducharme S, Tartaglia MC, Finger E, de Mendonça A, Santana I, Sanchez-Valle R, Moreno F, Sorbi S, Tagliavini F, Borroni B, Otto M, Synofzik M, Galimberti D, Vandenberghe R, van Swieten J, Butler C, Gerhard A, Graff C, Danek A, Rohrer JD, Masellis M, Rowe J, Levin J; Genetic Frontotemporal Dementia Intiative (GENFI) (2022). Frequency and Longitudinal Course of Motor Signs In Genetic Frontotemporal Dementia. Neurology. 2022 Aug 10:10.1212/WNL.0000000000200828. doi: 10.1212/WNL.0000000000200828. Epub ahead of print. PMID: 35948443.
                                                          • Steward A, Biel D, Brendel M, Dewenter A, Roemer S, Rubinski A, Luan Y, Dichgans M, Ewers M, Franzmeier N; Alzheimer's Disease Neuroimaging Initiative (ADNI) (2022). Functional network segregation is associated with attenuated tau spreading in Alzheimer's disease. Alzheimers Dement. 2022 Nov 25. doi: 10.1002/alz.12867. Epub ahead of print. PMID: 36433865.
                                                          • Vöglein J, Franzmeier N, Morris JC, Dieterich M, McDade E, Simons M, Preische O, Hofmann A, Hassenstab J, Benzinger TL, Fagan A, Noble JM, Berman SB, Graff-Radford NR, Ghetti B, Farlow MR, Chhatwal JP, Salloway S, Xiong C, Karch CM, Cairns N, Perrin RJ, Day G, Martins R, Sanchez-Valle R, Mori H, Shimada H, Ikeuchi T, Suzuki K, Schofield PR, Masters CL, Goate A, Buckles V, Fox NC, Chrem P, Allegri R, Ringman JM, Yakushev I, Laske C, Jucker M, Höglinger G, Bateman RJ, Danek A, Levin J, Dominantly Inherited Alzheimer Network (2022). Pattern and implications of neurological examination findings in autosomal dominant Alzheimer disease. Alzheimers Dement. 2022 May 24. doi: 10.1002/alz.12684. Epub ahead of print. PMID: 35609137.
                                                          • Völter F, Beyer L, Eckenweber F, Scheifele M, Bui N, Patt M, Barthel H, Katzdobler S, Palleis C, Franzmeier N, Levin J, Perneczky R, Rauchmann BS, Sabri O, Hong J, Cumming P, Rominger A, Shi K, Bartenstein P, Brendel M (2022). Assessment of perfusion deficit with early phases of [18F]PI-2620 tau-PET versus [18F]flutemetamol-amyloid-PET recordings. Eur J Nucl Med Mol Imaging. 2022 Dec 27. doi: 10.1007/s00259-022-06087-y. Epub ahead of print. PMID: 36572740.

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                                                          SyNergy is funded by the Deutsche Forschungsgemeinschaft (German Research Foundation) within the framework of the German Excellence Strategy (EXC 2145 SyNergy – ID 390857198). The Excellence Strategy promotes outstanding research at German universities. 

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