News | 14/08/2024 | Press Release

Stopping and reversing Alzheimer's at an early stage

In the fight against Alzheimer's, researchers at the Technical University of Munich (TUM) have developed a promising, preventative therapeutic approach. They specifically targeted the amyloid beta biomolecule, which triggers the hyperactivity of nerve cells typical of the brain disease in its early stages. The team led by Dr. Benedikt Zott and Prof. Arthur Konnerth from the TUM School of Medicine and Health and Prof. Arne Skerra from the TUM School of Life Sciences succeeded in developing and using a protein drug that can suppress the effects of the harmful molecule.
Researching Alzheimer's: Prof. Arthur Konnerth and Dr. Benedikt Zott from the TUM School of Medicine and Health 

The study was published in the renowned journal "Nature Communications". The results obtained on mice in the laboratory indicate that neuronal dysfunctions could even be repaired. The researchers hope that the protein they investigated, which experts call amyloid-beta-binding anticalin (H1GA), can halt the progression of the severe neurodegenerative disease at an early stage