The Banco Bilbao Vizcaya Argentaria (BBVA) Foundation has honored Franz-Ulrich Hartl, Director at the Max Planck Institute of Biochemistry in Martinsried, with the BBVA Foundation Frontiers of Knowledge Prize in the category "Biology and Biomedicine". The biochemist receives the honor together with his colleagues: Arthur Horwich, Kazutoshi Mori, and Peter Walter. The scientists unraveled the physiological mechanisms behind protein folding, a fundamental finding to elucidate the origin of multiple diseases and develop new therapeutic strategies. The prize has been awarded in eight categories since 2008 and is endowed with 400,000 euros each.