Atherosclerosis - How diseased blood vessels communicate with the brain

Laboratories worldwide are carrying out research into the disease atherosclerosis. However, their focus is on atherosclerotic plaques – deposits of cholesterol, fibrous tissue and immune cells that form in the inner layer of arteries. These plaques progressively constrict the lumen of the arteries, such that less oxygen can get to the body tissue. Heart attacks, strokes and peripheral occlusive disease (smoker’s leg) are among the known consequences.